| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the phenoxybenzamine-6451 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AKAP17A | A kinase (PRKA) anchor protein 17A |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ATF3 | activating transcription factor 3 |
| BEX4 | brain expressed, X-linked 4 |
| BTG2 | BTG family, member 2 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CREM | cAMP responsive element modulator |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
| FAS | Fas cell surface death receptor |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLJ42627 | uncharacterized LOC645644 |
| FOSL1 | FOS-like antigen 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GNRHR | gonadotropin-releasing hormone receptor |
| HBEGF | heparin-binding EGF-like growth factor |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HGD | homogentisate 1,2-dioxygenase |
| HMOX1 | heme oxygenase 1 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IL6R | interleukin 6 receptor |
| INHBE | inhibin, beta E |
| IRS2 | insulin receptor substrate 2 |
| JMJD6 | jumonji domain containing 6 |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| LOC157562 | uncharacterized LOC157562 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta |
| MIR22HG | MIR22 host gene |
| MST1 | macrophage stimulating 1 |
| MT1F | metallothionein 1F |
| MT1G | metallothionein 1G |
| MT1H | metallothionein 1H |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like |
| MXD4 | MAX dimerization protein 4 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NHLH2 | nescient helix loop helix 2 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PIGO | phosphatidylinositol glycan anchor biosynthesis, class O |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| POPDC3 | popeye domain containing 3 |
| POU2F2 | POU class 2 homeobox 2 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| RAI2 | retinoic acid induced 2 |
| RFPL2 | ret finger protein-like 2 |
| RGS2 | regulator of G-protein signaling 2 |
| RGS20 | regulator of G-protein signaling 20 |
| RNF19B | ring finger protein 19B |
| RSL1D1 | ribosomal L1 domain containing 1 |
| SIRT4 | sirtuin 4 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMEK1 | SMEK homolog 1, suppressor of mek1 (Dictyostelium) |
| SPEF1 | sperm flagellar 1 |
| TES | testin LIM domain protein |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TREX1 | three prime repair exonuclease 1 |
| TRIM36 | tripartite motif containing 36 |
| TXNRD1 | thioredoxin reductase 1 |
| ULBP2 | UL16 binding protein 2 |
| UNKL | unkempt family zinc finger-like |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF432 | zinc finger protein 432 |
| ZNF606 | zinc finger protein 606 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARRB2 | arrestin, beta 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B3GNT1 | |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CHML | choroideremia-like (Rab escort protein 2) |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CISH | cytokine inducible SH2-containing protein |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| E2F8 | E2F transcription factor 8 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| FAR2 | fatty acyl CoA reductase 2 |
| FBXO5 | F-box protein 5 |
| FCHSD2 | FCH and double SH3 domains 2 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| FZD2 | frizzled class receptor 2 |
| FZD4 | frizzled class receptor 4 |
| GHR | growth hormone receptor |
| GLI3 | GLI family zinc finger 3 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H1D | histone cluster 1, H1d |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KIF23 | kinesin family member 23 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LOC390998 | ribosomal protein L10 pseudogene |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MCM10 | minichromosome maintenance complex component 10 |
| MEIS1 | Meis homeobox 1 |
| METTL1 | methyltransferase like 1 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MXD3 | MAX dimerization protein 3 |
| NCAM2 | neural cell adhesion molecule 2 |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDC80 | NDC80 kinetochore complex component |
| NDE1 | nudE neurodevelopment protein 1 |
| NEK11 | NIMA-related kinase 11 |
| OLFML2A | olfactomedin-like 2A |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PHACTR4 | phosphatase and actin regulator 4 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PRR15L | proline rich 15-like |
| PRR3 | proline rich 3 |
| RBL1 | retinoblastoma-like 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIN2 | Ras and Rab interactor 2 |
| RNF121 | ring finger protein 121 |
| RUNDC3B | RUN domain containing 3B |
| SASH1 | SAM and SH3 domain containing 1 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SSBP2 | single-stranded DNA binding protein 2 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| STON1 | stonin 1 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYTL2 | synaptotagmin-like 2 |
| TAOK3 | TAO kinase 3 |
| TARP | TCR gamma alternate reading frame protein |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM223 | transmembrane protein 223 |
| TRAF5 | TNF receptor-associated factor 5 |
| TRIM45 | tripartite motif containing 45 |
| TTBK2 | tau tubulin kinase 2 |
| TTC28 | tetratricopeptide repeat domain 28 |
| TWF2 | twinfilin actin binding protein 2 |
| TXNIP | thioredoxin interacting protein |
| UBTF | upstream binding transcription factor, RNA polymerase I |
| USP18 | ubiquitin specific peptidase 18 |
| VASH1 | vasohibin 1 |
| WDR62 | WD repeat domain 62 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| YEATS4 | YEATS domain containing 4 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF248 | zinc finger protein 248 |
| ZNF586 | zinc finger protein 586 |
