phensuximide-3521 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the phensuximide-3521 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ADAMTSL4 ADAMTS-like 4
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
AMBP alpha-1-microglobulin/bikunin precursor
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGAP35 Rho GTPase activating protein 35
ATAT1 alpha tubulin acetyltransferase 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BMP6 bone morphogenetic protein 6
C8ORF4 chromosome 8 open reading frame 4
C9ORF156 chromosome 9 open reading frame 156
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit
CARTPT CART prepropeptide
CD300C CD300c molecule
CD34 CD34 molecule
CD40LG CD40 ligand
CDC25C cell division cycle 25C
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
COPZ2 coatomer protein complex, subunit zeta 2
DGKE diacylglycerol kinase, epsilon 64kDa
DMP1 dentin matrix acidic phosphoprotein 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DSC3 desmocollin 3
DSCAM Down syndrome cell adhesion molecule
DUSP6 dual specificity phosphatase 6
EML2 echinoderm microtubule associated protein like 2
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
FADS2 fatty acid desaturase 2
FASLG Fas ligand (TNF superfamily, member 6)
FBXO41 F-box protein 41
FCGBP Fc fragment of IgG binding protein
FRMPD4 FERM and PDZ domain containing 4
FSTL1 follistatin-like 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GSK3A glycogen synthase kinase 3 alpha
HDAC5 histone deacetylase 5
ICOSLG inducible T-cell co-stimulator ligand
IFT140 intraflagellar transport 140
IL2RG interleukin 2 receptor, gamma
INHBA inhibin, beta A
KRT31 keratin 31, type I
KRT4 keratin 4, type II
LOC79999 uncharacterized LOC79999
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MAL mal, T-cell differentiation protein
NCR2 natural cytotoxicity triggering receptor 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NPFF neuropeptide FF-amide peptide precursor
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
PBOV1 prostate and breast cancer overexpressed 1
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDZD3 PDZ domain containing 3
PRB1 proline-rich protein BstNI subfamily 1
PXDC1 PX domain containing 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RGS14 regulator of G-protein signaling 14
RND1 Rho family GTPase 1
RPS3A ribosomal protein S3A
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SCUBE3 signal peptide, CUB domain, EGF-like 3
SDC2 syndecan 2
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC25A30 solute carrier family 25, member 30
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SOX15 SRY (sex determining region Y)-box 15
SP110 SP110 nuclear body protein
SSTR5 somatostatin receptor 5
STS steroid sulfatase (microsomal), isozyme S
SUSD5 sushi domain containing 5
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYBU syntabulin (syntaxin-interacting)
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TEX15 testis expressed 15
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TLDC1 TBC/LysM-associated domain containing 1
TM4SF5 transmembrane 4 L six family member 5
TMPRSS4 transmembrane protease, serine 4
TOP3B topoisomerase (DNA) III beta
TRIM14 tripartite motif containing 14
TTC38 tetratricopeptide repeat domain 38
TUBBP5 tubulin, beta pseudogene 5
UNC5B unc-5 homolog B (C. elegans)
UPK2 uroplakin 2
VTCN1 V-set domain containing T cell activation inhibitor 1
WBP5 WW domain binding protein 5
WDR1 WD repeat domain 1
ZNF280A zinc finger protein 280A
ZNF358 zinc finger protein 358
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADAP2 ArfGAP with dual PH domains 2
ADGRE5 adhesion G protein-coupled receptor E5
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
C11ORF30 chromosome 11 open reading frame 30
C19ORF73 chromosome 19 open reading frame 73
C1QTNF3 C1q and tumor necrosis factor related protein 3
C7ORF43 chromosome 7 open reading frame 43
CBX8 chromobox homolog 8
CCDC68 coiled-coil domain containing 68
CCDC85C coiled-coil domain containing 85C
CCS copper chaperone for superoxide dismutase
CORT cortistatin
CRY2 cryptochrome circadian clock 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
CTSF cathepsin F
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DEAF1 DEAF1 transcription factor
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
ELOVL4 ELOVL fatty acid elongase 4
ERO1L ERO1-like (S. cerevisiae)
ETAA1 Ewing tumor-associated antigen 1
FAM46C family with sequence similarity 46, member C
FBXL6 F-box and leucine-rich repeat protein 6
FBXW12 F-box and WD repeat domain containing 12
FLNC filamin C, gamma
FRMD1 FERM domain containing 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GSTA4 glutathione S-transferase alpha 4
GTPBP2 GTP binding protein 2
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AK histone cluster 1, H2ak
HIST1H2BO histone cluster 1, H2bo
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
INO80D INO80 complex subunit D
KDM5C lysine (K)-specific demethylase 5C
KIF13B kinesin family member 13B
KIFAP3 kinesin-associated protein 3
KLF7 Kruppel-like factor 7 (ubiquitous)
LAX1 lymphocyte transmembrane adaptor 1
LINC00339 long intergenic non-protein coding RNA 339
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MAGEA3 melanoma antigen family A3
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MBNL3 muscleblind-like splicing regulator 3
MICALL2 MICAL-like 2
MITF microphthalmia-associated transcription factor
MOGS mannosyl-oligosaccharide glucosidase
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
NFE2L3 nuclear factor, erythroid 2-like 3
NOL12 nucleolar protein 12
NPFFR1 neuropeptide FF receptor 1
NPTX1 neuronal pentraxin I
P3H1 prolyl 3-hydroxylase 1
PALM paralemmin
PARP12 poly (ADP-ribose) polymerase family, member 12
PDIA3 protein disulfide isomerase family A, member 3
PLD3 phospholipase D family, member 3
PNPLA6 patatin-like phospholipase domain containing 6
PODXL2 podocalyxin-like 2
POPDC3 popeye domain containing 3
PPT2 palmitoyl-protein thioesterase 2
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
R3HCC1L R3H domain and coiled-coil containing 1-like
RASL11B RAS-like, family 11, member B
RLN1 relaxin 1
RNF126P1 ring finger protein 126 pseudogene 1
RPAP1 RNA polymerase II associated protein 1
RPL10L ribosomal protein L10-like
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SMA4 glucuronidase, beta pseudogene
SP1 Sp1 transcription factor
SREK1IP1 SREK1-interacting protein 1
SRPX sushi-repeat containing protein, X-linked
STARD3 StAR-related lipid transfer (START) domain containing 3
TET3 tet methylcytosine dioxygenase 3
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMLHE trimethyllysine hydroxylase, epsilon
TRIM25 tripartite motif containing 25
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSGA10 testis specific, 10
UBQLN4 ubiquilin 4
UPP1 uridine phosphorylase 1
VAX2 ventral anterior homeobox 2
VGF VGF nerve growth factor inducible
WLS wntless Wnt ligand secretion mediator
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZC3H3 zinc finger CCCH-type containing 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFAND3 zinc finger, AN1-type domain 3
ZNF205 zinc finger protein 205
ZNF652 zinc finger protein 652
ZNF701 zinc finger protein 701