phensuximide-5097 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the phensuximide-5097 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AASS aminoadipate-semialdehyde synthase
ACRV1 acrosomal vesicle protein 1
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APC adenomatous polyposis coli
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BMP1 bone morphogenetic protein 1
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCL27 chemokine (C-C motif) ligand 27
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CHD5 chromodomain helicase DNA binding protein 5
CHN2 chimerin 2
CNGB3 cyclic nucleotide gated channel beta 3
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CST1 cystatin SN
CTNND2 catenin (cadherin-associated protein), delta 2
EPHA1 EPH receptor A1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM120C family with sequence similarity 120C
FBXO31 F-box protein 31
FGF18 fibroblast growth factor 18
FOXN2 forkhead box N2
FRMPD1 FERM and PDZ domain containing 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GRIK5 glutamate receptor, ionotropic, kainate 5
GRM4 glutamate receptor, metabotropic 4
GRTP1 growth hormone regulated TBC protein 1
HCRP1 hepatocellular carcinoma-related HCRP1
HRK harakiri, BCL2 interacting protein
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL2RG interleukin 2 receptor, gamma
INE1 inactivation escape 1 (non-protein coding)
KANSL3 KAT8 regulatory NSL complex subunit 3
KCTD13 potassium channel tetramerization domain containing 13
KDM8 lysine (K)-specific demethylase 8
KLHL25 kelch-like family member 25
KLHL36 kelch-like family member 36
LPAR4 lysophosphatidic acid receptor 4
LRRC1 leucine rich repeat containing 1
LYPLA2P1 lysophospholipase II pseudogene 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MRC2 mannose receptor, C type 2
MST1 macrophage stimulating 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NDRG2 NDRG family member 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOVA1 neuro-oncological ventral antigen 1
OLFM4 olfactomedin 4
PALM paralemmin
PDE12 phosphodiesterase 12
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDZRN3 PDZ domain containing ring finger 3
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PIDD1 p53-induced death domain protein 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PPP5C protein phosphatase 5, catalytic subunit
PRDM9 PR domain containing 9
PRKX protein kinase, X-linked
PTPRB protein tyrosine phosphatase, receptor type, B
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBM12B-AS1 RBM12B antisense RNA 1
RDH8 retinol dehydrogenase 8 (all-trans)
RNF39 ring finger protein 39
RPL10 ribosomal protein L10
RUNX1 runt-related transcription factor 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH2D2A SH2 domain containing 2A
SIDT2 SID1 transmembrane family, member 2
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SORBS1 sorbin and SH3 domain containing 1
SPATA2L spermatogenesis associated 2-like
SPRR1A small proline-rich protein 1A
SPTAN1 spectrin, alpha, non-erythrocytic 1
STARD5 StAR-related lipid transfer (START) domain containing 5
TLN2 talin 2
TMEM53 transmembrane protein 53
TNS1 tensin 1
TOM1 target of myb1 (chicken)
TREX1 three prime repair exonuclease 1
TYMS thymidylate synthetase
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
VEZT vezatin, adherens junctions transmembrane protein
VIPR2 vasoactive intestinal peptide receptor 2
XDH xanthine dehydrogenase
YIPF4 Yip1 domain family, member 4
ZBTB43 zinc finger and BTB domain containing 43
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF214 zinc finger protein 214
ZNF268 zinc finger protein 268
ZNF44 zinc finger protein 44

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADCY6 adenylate cyclase 6
ADGRB2 adhesion G protein-coupled receptor B2
ALS2CL ALS2 C-terminal like
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANP32A-IT1 ANP32A intronic transcript 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BCAS3 breast carcinoma amplified sequence 3
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BTC betacellulin
C1ORF159 chromosome 1 open reading frame 159
C1ORF35 chromosome 1 open reading frame 35
CCDC25 coiled-coil domain containing 25
CENPO centromere protein O
CISH cytokine inducible SH2-containing protein
CLDN11 claudin 11
CLDN8 claudin 8
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRYBB2P1 crystallin, beta B2 pseudogene 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
F3 coagulation factor III (thromboplastin, tissue factor)
FAM186A family with sequence similarity 186, member A
FANCC Fanconi anemia, complementation group C
FBXL15 F-box and leucine-rich repeat protein 15
FBXO2 F-box protein 2
FBXO46 F-box protein 46
FIG4 FIG4 phosphoinositide 5-phosphatase
FRS2 fibroblast growth factor receptor substrate 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GDAP1 ganglioside induced differentiation associated protein 1
HIST1H2AI histone cluster 1, H2ai
HIST1H3C histone cluster 1, H3c
HOXC4 homeobox C4
HYI hydroxypyruvate isomerase (putative)
INCENP inner centromere protein antigens 135/155kDa
IPO8 importin 8
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
JUNB jun B proto-oncogene
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCTD20 potassium channel tetramerization domain containing 20
KDM5C lysine (K)-specific demethylase 5C
KIF13B kinesin family member 13B
LIME1 Lck interacting transmembrane adaptor 1
LINC00339 long intergenic non-protein coding RNA 339
LOC257152 uncharacterized LOC257152
LOC390998 ribosomal protein L10 pseudogene
LOC730101 uncharacterized LOC730101
LZTR1 leucine-zipper-like transcription regulator 1
MAST3 microtubule associated serine/threonine kinase 3
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCC mutated in colorectal cancers
MED31 mediator complex subunit 31
MFSD6 major facilitator superfamily domain containing 6
MMP13 matrix metallopeptidase 13
MTERF4 mitochondrial transcription termination factor 4
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL10 nucleolar protein 10
NOTCH1 notch 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLCD1 phospholipase C, delta 1
POLH polymerase (DNA directed), eta
PRR4 proline rich 4 (lacrimal)
PTK7 protein tyrosine kinase 7 (inactive)
PTPRS protein tyrosine phosphatase, receptor type, S
QSER1 glutamine and serine rich 1
RBMS3 RNA binding motif, single stranded interacting protein 3
RNF121 ring finger protein 121
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
RPP25 ribonuclease P/MRP 25kDa subunit
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RWDD2A RWD domain containing 2A
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SFT2D2 SFT2 domain containing 2
SLC17A2 solute carrier family 17, member 2
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SNPH syntaphilin
TAGLN3 transgelin 3
TEX40 testis expressed 40
TRIM25 tripartite motif containing 25
TRIM45 tripartite motif containing 45
TUBA3D tubulin, alpha 3d
ZNF197 zinc finger protein 197
ZNF33B zinc finger protein 33B
ZNF529 zinc finger protein 529
ZNF816 zinc finger protein 816
ZNF93 zinc finger protein 93