phensuximide-5522 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the phensuximide-5522 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADCY6 adenylate cyclase 6
AGRP agouti related neuropeptide
ARID5A AT rich interactive domain 5A (MRF1-like)
ARL4C ADP-ribosylation factor-like 4C
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BANK1 B-cell scaffold protein with ankyrin repeats 1
BCAM basal cell adhesion molecule (Lutheran blood group)
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BTF3P11 basic transcription factor 3 pseudogene 11
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCR7 chemokine (C-C motif) receptor 7
CDK10 cyclin-dependent kinase 10
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CLEC1B C-type lectin domain family 1, member B
CLIP4 CAP-GLY domain containing linker protein family, member 4
COL14A1 collagen, type XIV, alpha 1
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
DLK2 delta-like 2 homolog (Drosophila)
DPT dermatopontin
DTNA dystrobrevin, alpha
EML2 echinoderm microtubule associated protein like 2
ESR1 estrogen receptor 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFBP1 fibroblast growth factor binding protein 1
FLT4 fms-related tyrosine kinase 4
FOSL2 FOS-like antigen 2
FOXG1 forkhead box G1
FOXO4 forkhead box O4
GBP1 guanylate binding protein 1, interferon-inducible
GIF gastric intrinsic factor (vitamin B synthesis)
HAL histidine ammonia-lyase
HBS1L HBS1-like translational GTPase
HHAT hedgehog acyltransferase
HRASLS2 HRAS-like suppressor 2
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFITM1 interferon induced transmembrane protein 1
IFNA14 interferon, alpha 14
IFT27 intraflagellar transport 27
IFT38 intraflagellar transport 38
IQCA1 IQ motif containing with AAA domain 1
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KITLG KIT ligand
KLHL35 kelch-like family member 35
KPNA5 karyopherin alpha 5 (importin alpha 6)
LTBP4 latent transforming growth factor beta binding protein 4
LUZP1 leucine zipper protein 1
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MMP25 matrix metallopeptidase 25
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTSS1L metastasis suppressor 1-like
MYO9B myosin IXB
NAT6 N-acetyltransferase 6 (GCN5-related)
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NRF1 nuclear respiratory factor 1
NT5M 5',3'-nucleotidase, mitochondrial
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PAX2 paired box 2
PCBP3 poly(rC) binding protein 3
PCDHB3 protocadherin beta 3
PDCD2 programmed cell death 2
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDLIM7 PDZ and LIM domain 7 (enigma)
PLCD1 phospholipase C, delta 1
PLXNB1 plexin B1
POLL polymerase (DNA directed), lambda
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRB1 proline-rich protein BstNI subfamily 1
PRKCH protein kinase C, eta
QKI QKI, KH domain containing, RNA binding
RAB6B RAB6B, member RAS oncogene family
RBMS2 RNA binding motif, single stranded interacting protein 2
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPL10L ribosomal protein L10-like
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SSX1 synovial sarcoma, X breakpoint 1
SYN2 synapsin II
SYNDIG1 synapse differentiation inducing 1
TAPBP TAP binding protein (tapasin)
TBC1D22A TBC1 domain family, member 22A
TICAM1 toll-like receptor adaptor molecule 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
TNS1 tensin 1
TNS2 tensin 2
UPK3B uroplakin 3B
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WNT10B wingless-type MMTV integration site family, member 10B
ZC3H13 zinc finger CCCH-type containing 13
ZC3H7B zinc finger CCCH-type containing 7B
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF24 zinc finger protein 24
ZNF79 zinc finger protein 79
ZYX zyxin

decreased expression

Symbol Name
ACAD8 acyl-CoA dehydrogenase family, member 8
ADGRE5 adhesion G protein-coupled receptor E5
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AKAP12 A kinase (PRKA) anchor protein 12
ASPHD1 aspartate beta-hydroxylase domain containing 1
ATP11B ATPase, class VI, type 11B
BAG4 BCL2-associated athanogene 4
BIRC7 baculoviral IAP repeat containing 7
C5 complement component 5
C8ORF60 chromosome 8 open reading frame 60
CAMTA2 calmodulin binding transcription activator 2
CBX4 chromobox homolog 4
CCDC85C coiled-coil domain containing 85C
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CES3 carboxylesterase 3
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COPS7B COP9 signalosome subunit 7B
DCUN1D2 DCN1, defective in cullin neddylation 1, domain containing 2
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DENND5A DENN/MADD domain containing 5A
DHRS3 dehydrogenase/reductase (SDR family) member 3
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding)
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNAL4 dynein, axonemal, light chain 4
EAF2 ELL associated factor 2
ELOVL4 ELOVL fatty acid elongase 4
ELP3 elongator acetyltransferase complex subunit 3
ELSPBP1 epididymal sperm binding protein 1
FANCC Fanconi anemia, complementation group C
FBXL15 F-box and leucine-rich repeat protein 15
FOSL1 FOS-like antigen 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
HIST1H1D histone cluster 1, H1d
HOXC10 homeobox C10
IFNAR1 interferon (alpha, beta and omega) receptor 1
IMPACT impact RWD domain protein
ISG15 ISG15 ubiquitin-like modifier
KIAA0355 KIAA0355
LOC390998 ribosomal protein L10 pseudogene
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRP2 low density lipoprotein receptor-related protein 2
LZTR1 leucine-zipper-like transcription regulator 1
MAMLD1 mastermind-like domain containing 1
MAP1S microtubule-associated protein 1S
MCOLN3 mucolipin 3
MFSD11 major facilitator superfamily domain containing 11
MGC12488
MOSPD3 motile sperm domain containing 3
MRPL41 mitochondrial ribosomal protein L41
MRPL44 mitochondrial ribosomal protein L44
NPY5R neuropeptide Y receptor Y5
NR2C2 nuclear receptor subfamily 2, group C, member 2
NUBPL nucleotide binding protein-like
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
ONECUT2 one cut homeobox 2
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCDHA9 protocadherin alpha 9
PGBD5 piggyBac transposable element derived 5
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLA2G3 phospholipase A2, group III
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
POPDC3 popeye domain containing 3
PRSS22 protease, serine, 22
PTDSS2 phosphatidylserine synthase 2
PTK6 protein tyrosine kinase 6
PYCRL pyrroline-5-carboxylate reductase-like
RAB3A RAB3A, member RAS oncogene family
RFTN1 raftlin, lipid raft linker 1
RNF2 ring finger protein 2
SAV1 salvador family WW domain containing protein 1
SCAI suppressor of cancer cell invasion
SCGB2A2 secretoglobin, family 2A, member 2
SCIN scinderin
SCN1B sodium channel, voltage gated, type I beta subunit
SCUBE2 signal peptide, CUB domain, EGF-like 2
SIK1 salt-inducible kinase 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3 stromal antigen 3
TCTN2 tectonic family member 2
TGFBR3 transforming growth factor, beta receptor III
TMC7 transmembrane channel-like 7
TMEM180 transmembrane protein 180
TMEM209 transmembrane protein 209
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPRA1 transmembrane protein, adipocyte asscociated 1
TUBA3C tubulin, alpha 3c
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
XYLT2 xylosyltransferase II
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZNF276 zinc finger protein 276
ZNF408 zinc finger protein 408
ZNF571 zinc finger protein 571
ZSCAN31 zinc finger and SCAN domain containing 31