| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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197 genes differentially expressed following the phentolamine-1138 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABLIM1 | actin binding LIM protein 1 |
| ADCK3 | aarF domain containing kinase 3 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| ATM | ATM serine/threonine kinase |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
| ATXN1 | ataxin 1 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BMP7 | bone morphogenetic protein 7 |
| C16ORF62 | chromosome 16 open reading frame 62 |
| C19ORF54 | chromosome 19 open reading frame 54 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CALHM2 | calcium homeostasis modulator 2 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CDC40 | cell division cycle 40 |
| CLEC16A | C-type lectin domain family 16, member A |
| CPT1A | carnitine palmitoyltransferase 1A (liver) |
| CTTN | cortactin |
| CYB561 | cytochrome b561 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNMBP | dynamin binding protein |
| DPH5 | diphthamide biosynthesis 5 |
| ELF4 | E74-like factor 4 (ets domain transcription factor) |
| FASTK | Fas-activated serine/threonine kinase |
| FKBP2 | FK506 binding protein 2, 13kDa |
| FNTB | farnesyltransferase, CAAX box, beta |
| FPGS | folylpolyglutamate synthase |
| GLIPR1 | GLI pathogenesis-related 1 |
| GPR19 | G protein-coupled receptor 19 |
| GSTM1 | glutathione S-transferase mu 1 |
| HEMK1 | HemK methyltransferase family member 1 |
| HIST1H2BG | histone cluster 1, H2bg |
| HLA-E | major histocompatibility complex, class I, E |
| HMOX2 | heme oxygenase 2 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 |
| HSPA2 | heat shock 70kDa protein 2 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITM2B | integral membrane protein 2B |
| JUN | jun proto-oncogene |
| KAT5 | K(lysine) acetyltransferase 5 |
| LYPLA2 | lysophospholipase II |
| MARC2 | mitochondrial amidoxime reducing component 2 |
| MECP2 | methyl CpG binding protein 2 |
| MED14 | mediator complex subunit 14 |
| MTA1 | metastasis associated 1 |
| MTCL1 | microtubule crosslinking factor 1 |
| MTHFSD | methenyltetrahydrofolate synthetase domain containing |
| MXD3 | MAX dimerization protein 3 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) |
| NOTCH1 | notch 1 |
| OSBP | oxysterol binding protein |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PODXL | podocalyxin-like |
| POLR3C | polymerase (RNA) III (DNA directed) polypeptide C (62kD) |
| POMZP3 | POM121 and ZP3 fusion |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PRUNE | prune exopolyphosphatase |
| RAP1GAP | RAP1 GTPase activating protein |
| RHOF | ras homolog family member F (in filopodia) |
| RHOT2 | ras homolog family member T2 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SIKE1 | suppressor of IKBKE 1 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STBD1 | starch binding domain 1 |
| STC1 | stanniocalcin 1 |
| STK10 | serine/threonine kinase 10 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYK | spleen tyrosine kinase |
| TELO2 | telomere maintenance 2 |
| THAP1 | THAP domain containing, apoptosis associated protein 1 |
| TMEM115 | transmembrane protein 115 |
| TMEM39B | transmembrane protein 39B |
| TRAPPC6A | trafficking protein particle complex 6A |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBAP1 | ubiquitin associated protein 1 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 |
| UPF1 | UPF1 regulator of nonsense transcripts homolog (yeast) |
| ZBTB14 | zinc finger and BTB domain containing 14 |
| ZNF318 | zinc finger protein 318 |
| ZNF574 | zinc finger protein 574 |
| ZNF580 | zinc finger protein 580 |
| ZNF75D | zinc finger protein 75D |
| ZNF813 | zinc finger protein 813 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ADIRF | adipogenesis regulatory factor |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATG7 | autophagy related 7 |
| ATP11B | ATPase, class VI, type 11B |
| AXIN1 | axin 1 |
| AZI2 | 5-azacytidine induced 2 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BCL2L2 | BCL2-like 2 |
| BLM | Bloom syndrome, RecQ helicase-like |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CBX4 | chromobox homolog 4 |
| CCDC176 | coiled-coil domain containing 176 |
| CCNJ | cyclin J |
| CDK5 | cyclin-dependent kinase 5 |
| CENPJ | centromere protein J |
| CENPT | centromere protein T |
| CEP83 | centrosomal protein 83kDa |
| CLASRP | CLK4-associating serine/arginine rich protein |
| CLDND1 | claudin domain containing 1 |
| CPTP | ceramide-1-phosphate transfer protein |
| CRBN | cereblon |
| CRYL1 | crystallin, lambda 1 |
| DCAF10 | DDB1 and CUL4 associated factor 10 |
| DCP1A | decapping mRNA 1A |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| DMXL1 | Dmx-like 1 |
| EDC4 | enhancer of mRNA decapping 4 |
| EPPK1 | epiplakin 1 |
| FEM1C | fem-1 homolog c (C. elegans) |
| FLJ10038 | uncharacterized protein FLJ10038 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GAB2 | GRB2-associated binding protein 2 |
| GLMN | glomulin, FKBP associated protein |
| GMPPA | GDP-mannose pyrophosphorylase A |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HMBOX1 | homeobox containing 1 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IL10RB | interleukin 10 receptor, beta |
| INPP5A | inositol polyphosphate-5-phosphatase, 40kDa |
| IPP | intracisternal A particle-promoted polypeptide |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KIAA0125 | KIAA0125 |
| KIF3A | kinesin family member 3A |
| KLK6 | kallikrein-related peptidase 6 |
| LAMA5 | laminin, alpha 5 |
| LIN37 | lin-37 DREAM MuvB core complex component |
| LRRC16A | leucine rich repeat containing 16A |
| MANSC1 | MANSC domain containing 1 |
| MICB | MHC class I polypeptide-related sequence B |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MPST | mercaptopyruvate sulfurtransferase |
| MRPL17 | mitochondrial ribosomal protein L17 |
| NIT1 | nitrilase 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NUBPL | nucleotide binding protein-like |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PIGA | phosphatidylinositol glycan anchor biosynthesis, class A |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PPCDC | phosphopantothenoylcysteine decarboxylase |
| PRKCH | protein kinase C, eta |
| PRPF39 | pre-mRNA processing factor 39 |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RBM6 | RNA binding motif protein 6 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| RUFY2 | RUN and FYVE domain containing 2 |
| SETD6 | SET domain containing 6 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 |
| SIRAL2 | SIR2 antiphage like 2 |
| SIRT1 | sirtuin 1 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC35A5 | solute carrier family 35, member A5 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBCCD1 | TBCC domain containing 1 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM57 | transmembrane protein 57 |
| TRAPPC2 | trafficking protein particle complex 2 |
| TRIM52 | tripartite motif containing 52 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TTC17 | tetratricopeptide repeat domain 17 |
| TTI1 | TELO2 interacting protein 1 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| USP6 | ubiquitin specific peptidase 6 |
| WDR60 | WD repeat domain 60 |
| YAP1 | Yes-associated protein 1 |
| ZNF611 | zinc finger protein 611 |
| ZNF85 | zinc finger protein 85 |