| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the phentolamine-2362 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACO2 | aconitase 2, mitochondrial |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AQP4 | aquaporin 4 |
| ARL4C | ADP-ribosylation factor-like 4C |
| B4GALT7 | xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BCL2 | B-cell CLL/lymphoma 2 |
| BHMT2 | betaine--homocysteine S-methyltransferase 2 |
| C1ORF21 | chromosome 1 open reading frame 21 |
| CA1 | carbonic anhydrase I |
| CABP2 | calcium binding protein 2 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CD7 | CD7 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| COMT | catechol-O-methyltransferase |
| CPNE7 | copine VII |
| CTRL | chymotrypsin-like |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DBN1 | drebrin 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DXO | decapping exoribonuclease |
| EHBP1L1 | EH domain binding protein 1-like 1 |
| EMC1 | ER membrane protein complex subunit 1 |
| FAM63A | family with sequence similarity 63, member A |
| FBN1 | fibrillin 1 |
| FLJ11292 | |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GH1 | growth hormone 1 |
| GNS | glucosamine (N-acetyl)-6-sulfatase |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GSDMD | gasdermin D |
| HFE | hemochromatosis |
| HIST1H1T | histone cluster 1, H1t |
| HOXA10 | homeobox A10 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| INPP5K | inositol polyphosphate-5-phosphatase K |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KLHL22 | kelch-like family member 22 |
| KLK2 | kallikrein-related peptidase 2 |
| LAMB4 | laminin, beta 4 |
| LARP7 | La ribonucleoprotein domain family, member 7 |
| LIMD2 | LIM domain containing 2 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| MGLL | monoglyceride lipase |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NEBL | nebulette |
| NXF2 | nuclear RNA export factor 2 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase |
| OSBPL10 | oxysterol binding protein-like 10 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAX2 | paired box 2 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PQBP1 | polyglutamine binding protein 1 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RALGPS1 | Ral GEF with PH domain and SH3 binding motif 1 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RCAN1 | regulator of calcineurin 1 |
| REST | RE1-silencing transcription factor |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RNF122 | ring finger protein 122 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RUFY3 | RUN and FYVE domain containing 3 |
| RYK | receptor-like tyrosine kinase |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPN | sialophorin |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| TMPRSS15 | transmembrane protease, serine 15 |
| TNS2 | tensin 2 |
| TPMT | thiopurine S-methyltransferase |
| TRA | T cell receptor alpha locus |
| TRAPPC9 | trafficking protein particle complex 9 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| UGCG | UDP-glucose ceramide glucosyltransferase |
| USB1 | U6 snRNA biogenesis 1 |
| WNT6 | wingless-type MMTV integration site family, member 6 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| Symbol | Name |
|---|---|
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ACO1 | aconitase 1, soluble |
| ACPP | acid phosphatase, prostate |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AGO2 | argonaute RISC catalytic component 2 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| ALPK1 | alpha-kinase 1 |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APOL6 | apolipoprotein L, 6 |
| ASF1B | anti-silencing function 1B histone chaperone |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CARD9 | caspase recruitment domain family, member 9 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD151 | CD151 molecule (Raph blood group) |
| CD1D | CD1d molecule |
| CDC37L1 | cell division cycle 37-like 1 |
| CEL | carboxyl ester lipase |
| CENPB | centromere protein B, 80kDa |
| CLDN15 | claudin 15 |
| CLSPN | claspin |
| CMTR1 | cap methyltransferase 1 |
| CTSD | cathepsin D |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DBF4B | DBF4 zinc finger B |
| DCLRE1A | DNA cross-link repair 1A |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DTWD1 | DTW domain containing 1 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ENAH | enabled homolog (Drosophila) |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FANCE | Fanconi anemia, complementation group E |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FKBPL | FK506 binding protein like |
| GMPPA | GDP-mannose pyrophosphorylase A |
| GPR183 | G protein-coupled receptor 183 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| ICK | intestinal cell (MAK-like) kinase |
| KIN | Kin17 DNA and RNA binding protein |
| LMAN2L | lectin, mannose-binding 2-like |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LRRC42 | leucine rich repeat containing 42 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| NCKAP1L | NCK-associated protein 1-like |
| NINJ1 | ninjurin 1 |
| OCEL1 | occludin/ELL domain containing 1 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PCYOX1 | prenylcysteine oxidase 1 |
| PDZD8 | PDZ domain containing 8 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PLA2G12A | phospholipase A2, group XIIA |
| PLGRKT | plasminogen receptor, C-terminal lysine transmembrane protein |
| PLS1 | plastin 1 |
| PMCH | pro-melanin-concentrating hormone |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTER | phosphotriesterase related |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RASA2 | RAS p21 protein activator 2 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SFT2D2 | SFT2 domain containing 2 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNIP1 | Smad nuclear interacting protein 1 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| TMEM183A | transmembrane protein 183A |
| TPCN1 | two pore segment channel 1 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TTBK2 | tau tubulin kinase 2 |
| USP19 | ubiquitin specific peptidase 19 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF227 | zinc finger protein 227 |
| ZNF33B | zinc finger protein 33B |
| ZNF430 | zinc finger protein 430 |
| ZNF529 | zinc finger protein 529 |
| ZNF586 | zinc finger protein 586 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
