| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
195 genes differentially expressed following the phentolamine-3779 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM19 | ADAM metallopeptidase domain 19 |
| ADAM20 | ADAM metallopeptidase domain 20 |
| ADCK4 | aarF domain containing kinase 4 |
| ALDH6A1 | aldehyde dehydrogenase 6 family, member A1 |
| ALOX15B | arachidonate 15-lipoxygenase, type B |
| ALOX5 | arachidonate 5-lipoxygenase |
| ALPK1 | alpha-kinase 1 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| B3GAT1 | beta-1,3-glucuronyltransferase 1 |
| BBC3 | BCL2 binding component 3 |
| BMP1 | bone morphogenetic protein 1 |
| BMP10 | bone morphogenetic protein 10 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CASQ2 | calsequestrin 2 (cardiac muscle) |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLDN1 | claudin 1 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| CNPY4 | canopy FGF signaling regulator 4 |
| COL14A1 | collagen, type XIV, alpha 1 |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) |
| DIO2 | deiodinase, iodothyronine, type II |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| FAM63A | family with sequence similarity 63, member A |
| FGF21 | fibroblast growth factor 21 |
| FZD5 | frizzled class receptor 5 |
| GABRB3 | gamma-aminobutyric acid (GABA) A receptor, beta 3 |
| GFI1 | growth factor independent 1 transcription repressor |
| GHRHR | growth hormone releasing hormone receptor |
| GPR85 | G protein-coupled receptor 85 |
| GRB7 | growth factor receptor-bound protein 7 |
| GYG2 | glycogenin 2 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HES2 | hes family bHLH transcription factor 2 |
| IDS | iduronate 2-sulfatase |
| IFITM1 | interferon induced transmembrane protein 1 |
| IGF1R | insulin-like growth factor 1 receptor |
| IL1R1 | interleukin 1 receptor, type I |
| KANK2 | KN motif and ankyrin repeat domains 2 |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KIF1A | kinesin family member 1A |
| KLF13 | Kruppel-like factor 13 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| MLANA | melan-A |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MPPE1 | metallophosphoesterase 1 |
| MPZ | myelin protein zero |
| NPY | neuropeptide Y |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NUDC | nudC nuclear distribution protein |
| OBSL1 | obscurin-like 1 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PCP4 | Purkinje cell protein 4 |
| PDE11A | phosphodiesterase 11A |
| PDLIM3 | PDZ and LIM domain 3 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PTEN | phosphatase and tensin homolog |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RASSF9 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 |
| REC8 | REC8 meiotic recombination protein |
| RECQL5 | RecQ protein-like 5 |
| RGS6 | regulator of G-protein signaling 6 |
| RGS9 | regulator of G-protein signaling 9 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SLA | Src-like-adaptor |
| SLC24A2 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMAD6 | SMAD family member 6 |
| SNX13 | sorting nexin 13 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced |
| SYN3 | synapsin III |
| TACR1 | tachykinin receptor 1 |
| TEK | TEK tyrosine kinase, endothelial |
| TFEC | transcription factor EC |
| TFR2 | transferrin receptor 2 |
| TLE4 | transducin-like enhancer of split 4 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNXB | tenascin XB |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| UBXN1 | UBX domain protein 1 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZNF446 | zinc finger protein 446 |
| ZNF506 | zinc finger protein 506 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ARMC4 | armadillo repeat containing 4 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BAX | BCL2-associated X protein |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| CCDC186 | coiled-coil domain containing 186 |
| CCNJ | cyclin J |
| CDK3 | cyclin-dependent kinase 3 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CFAP45 | cilia and flagella associated protein 45 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CPNE7 | copine VII |
| CPZ | carboxypeptidase Z |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERF | Ets2 repressor factor |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO31 | F-box protein 31 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GAS8 | growth arrest-specific 8 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GTF2I | general transcription factor IIi |
| HCFC1 | host cell factor C1 |
| HDAC7 | histone deacetylase 7 |
| HIST1H2AL | histone cluster 1, H2al |
| HOXB2 | homeobox B2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL22 | interleukin 22 |
| ITK | IL2-inducible T-cell kinase |
| KIFC1 | kinesin family member C1 |
| KRT37 | keratin 37, type I |
| LOC157562 | uncharacterized LOC157562 |
| LRRC6 | leucine rich repeat containing 6 |
| MAGEF1 | melanoma antigen family F1 |
| MCC | mutated in colorectal cancers |
| MGC12488 | |
| MMRN2 | multimerin 2 |
| MTA2 | metastasis associated 1 family, member 2 |
| NEK11 | NIMA-related kinase 11 |
| NOL12 | nucleolar protein 12 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PALMD | palmdelphin |
| PAQR5 | progestin and adipoQ receptor family member V |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PEX26 | peroxisomal biogenesis factor 26 |
| PICK1 | protein interacting with PRKCA 1 |
| POLH | polymerase (DNA directed), eta |
| PQLC2 | PQ loop repeat containing 2 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB4B | RAB4B, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RFPL3 | ret finger protein-like 3 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF121 | ring finger protein 121 |
| RNF122 | ring finger protein 122 |
| RWDD2A | RWD domain containing 2A |
| SCG2 | secretogranin II |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| STRN | striatin, calmodulin binding protein |
| STXBP5L | syntaxin binding protein 5-like |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| THRB | thyroid hormone receptor, beta |
| TRIM25 | tripartite motif containing 25 |
| TRIM66 | tripartite motif containing 66 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF230 | zinc finger protein 230 |
| ZNF286A | zinc finger protein 286A |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF408 | zinc finger protein 408 |
| ZNF480 | zinc finger protein 480 |
| ZNF573 | zinc finger protein 573 |
| ZNF747 | zinc finger protein 747 |
| ZNF770 | zinc finger protein 770 |
| ZNF8 | zinc finger protein 8 |
