| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the phentolamine-3971 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AK1 | adenylate kinase 1 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ART1 | ADP-ribosyltransferase 1 |
| ATXN3 | ataxin 3 |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CARD10 | caspase recruitment domain family, member 10 |
| CCL5 | chemokine (C-C motif) ligand 5 |
| CD58 | CD58 molecule |
| CD6 | CD6 molecule |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CD86 | CD86 molecule |
| CD96 | CD96 molecule |
| CDK19 | cyclin-dependent kinase 19 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CPQ | carboxypeptidase Q |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| CYSLTR2 | cysteinyl leukotriene receptor 2 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DFNB31 | deafness, autosomal recessive 31 |
| EPB41L4A | erythrocyte membrane protein band 4.1 like 4A |
| ERCC2 | excision repair cross-complementation group 2 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FAM13C | family with sequence similarity 13, member C |
| FAM65B | family with sequence similarity 65, member B |
| FBLN1 | fibulin 1 |
| FLNC | filamin C, gamma |
| FXYD7 | FXYD domain containing ion transport regulator 7 |
| GAP43 | growth associated protein 43 |
| GH1 | growth hormone 1 |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GLRA1 | glycine receptor, alpha 1 |
| HOXD3 | homeobox D3 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| ITGB6 | integrin, beta 6 |
| IZUMO4 | IZUMO family member 4 |
| KLF1 | Kruppel-like factor 1 (erythroid) |
| KLHL22 | kelch-like family member 22 |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT14 | keratin 14, type I |
| LAMA4 | laminin, alpha 4 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LOXL2 | lysyl oxidase-like 2 |
| LUZP4 | leucine zipper protein 4 |
| MAGEC1 | melanoma antigen family C1 |
| MTL5 | metallothionein-like 5, testis-specific (tesmin) |
| MYCNOS | MYCN opposite strand |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NYNRIN | NYN domain and retroviral integrase containing |
| PARVB | parvin, beta |
| PAX1 | paired box 1 |
| PER1 | period circadian clock 1 |
| PLAT | plasminogen activator, tissue |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLXDC1 | plexin domain containing 1 |
| PQLC2 | PQ loop repeat containing 2 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRDX2 | peroxiredoxin 2 |
| RANBP3 | RAN binding protein 3 |
| REEP2 | receptor accessory protein 2 |
| RFPL1 | ret finger protein-like 1 |
| RFPL2 | ret finger protein-like 2 |
| RHAG | Rh-associated glycoprotein |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) |
| S100A7 | S100 calcium binding protein A7 |
| S100A9 | S100 calcium binding protein A9 |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SCNN1G | sodium channel, non voltage gated 1 gamma subunit |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SOX18 | SRY (sex determining region Y)-box 18 |
| SPN | sialophorin |
| SPRR2B | small proline-rich protein 2B |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| STOML1 | stomatin (EPB72)-like 1 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SYT11 | synaptotagmin XI |
| TAS2R4 | taste receptor, type 2, member 4 |
| TCF4 | transcription factor 4 |
| TDRD12 | tudor domain containing 12 |
| VPREB3 | pre-B lymphocyte 3 |
| ZNF154 | zinc finger protein 154 |
| ZNF440 | zinc finger protein 440 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| AMPD1 | adenosine monophosphate deaminase 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| B9D2 | B9 protein domain 2 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL2L2 | BCL2-like 2 |
| BMP10 | bone morphogenetic protein 10 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C1QB | complement component 1, q subcomponent, B chain |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CCNK | cyclin K |
| CES3 | carboxylesterase 3 |
| CFHR4 | complement factor H-related 4 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CLDN11 | claudin 11 |
| CLEC4E | C-type lectin domain family 4, member E |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DOCK4 | dedicator of cytokinesis 4 |
| DPY19L1P1 | DPY19L1 pseudogene 1 |
| DUSP9 | dual specificity phosphatase 9 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ETV6 | ets variant 6 |
| FAM110B | family with sequence similarity 110, member B |
| FAM131A | family with sequence similarity 131, member A |
| FAM155A | family with sequence similarity 155, member A |
| FAM76A | family with sequence similarity 76, member A |
| FBXL8 | F-box and leucine-rich repeat protein 8 |
| FFAR2 | free fatty acid receptor 2 |
| GAST | gastrin |
| GATA4 | GATA binding protein 4 |
| HDAC11 | histone deacetylase 11 |
| HIRA | histone cell cycle regulator |
| HIST1H4A | histone cluster 1, H4a |
| HIST1H4D | histone cluster 1, H4d |
| HIST1H4E | histone cluster 1, H4e |
| HMOX1 | heme oxygenase 1 |
| HOXC8 | homeobox C8 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KIAA0125 | KIAA0125 |
| KLRG1 | killer cell lectin-like receptor subfamily G, member 1 |
| KRT83 | keratin 83, type II |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MMP3 | matrix metallopeptidase 3 |
| MRPL41 | mitochondrial ribosomal protein L41 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NDE1 | nudE neurodevelopment protein 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NPTX1 | neuronal pentraxin I |
| PADI3 | peptidyl arginine deiminase, type III |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PODNL1 | podocan-like 1 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PRKCE | protein kinase C, epsilon |
| QSER1 | glutamine and serine rich 1 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIN1 | Ras and Rab interactor 1 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC41A3 | solute carrier family 41, member 3 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPRR1B | small proline-rich protein 1B |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SYNC | syncoilin, intermediate filament protein |
| TBC1D19 | TBC1 domain family, member 19 |
| TMEM120B | transmembrane protein 120B |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TRIM21 | tripartite motif containing 21 |
| TRIM36 | tripartite motif containing 36 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TSC22D4 | TSC22 domain family, member 4 |
| VN1R1 | vomeronasal 1 receptor 1 |
| XYLT2 | xylosyltransferase II |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF230 | zinc finger protein 230 |
| ZNF286A | zinc finger protein 286A |
| ZNF34 | zinc finger protein 34 |
| ZNF446 | zinc finger protein 446 |
| ZNF484 | zinc finger protein 484 |
| ZNF506 | zinc finger protein 506 |
| ZNF862 | zinc finger protein 862 |