| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the phentolamine-4336 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| ADCY1 | adenylate cyclase 1 (brain) |
| AIM1L | absent in melanoma 1-like |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ANGPTL4 | angiopoietin-like 4 |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| BBC3 | BCL2 binding component 3 |
| BHMT | betaine--homocysteine S-methyltransferase |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) |
| C10ORF10 | chromosome 10 open reading frame 10 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CCDC40 | coiled-coil domain containing 40 |
| CCNK | cyclin K |
| CD82 | CD82 molecule |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLEC4E | C-type lectin domain family 4, member E |
| CNTNAP2 | contactin associated protein-like 2 |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CPM | carboxypeptidase M |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CTNS | cystinosin, lysosomal cystine transporter |
| CTRL | chymotrypsin-like |
| CTSZ | cathepsin Z |
| CWH43 | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) |
| DCTN1 | dynactin 1 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DKFZP434C153 | DKFZP434C153 protein |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DOK1 | docking protein 1, 62kDa (downstream of tyrosine kinase 1) |
| DSCAM | Down syndrome cell adhesion molecule |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) |
| ELAC2 | elaC ribonuclease Z 2 |
| EPS8L3 | EPS8-like 3 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FAM63A | family with sequence similarity 63, member A |
| FCN1 | ficolin (collagen/fibrinogen domain containing) 1 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FGFR4 | fibroblast growth factor receptor 4 |
| FMO5 | flavin containing monooxygenase 5 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| HFE | hemochromatosis |
| HIST1H3E | histone cluster 1, H3e |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IDS | iduronate 2-sulfatase |
| IL11 | interleukin 11 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 |
| IQSEC2 | IQ motif and Sec7 domain 2 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| ITGB5 | integrin, beta 5 |
| KIF5A | kinesin family member 5A |
| KRT7 | keratin 7, type II |
| LAT2 | linker for activation of T cells family, member 2 |
| LOC157562 | uncharacterized LOC157562 |
| MAGEA1 | melanoma antigen family A1 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MMP10 | matrix metallopeptidase 10 |
| NDNF | neuron-derived neurotrophic factor |
| NPTXR | neuronal pentraxin receptor |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| OLFM1 | olfactomedin 1 |
| OLFML2B | olfactomedin-like 2B |
| OSBPL10 | oxysterol binding protein-like 10 |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLXNA2 | plexin A2 |
| POU2F2 | POU class 2 homeobox 2 |
| RAB6A | RAB6A, member RAS oncogene family |
| RASAL2 | RAS protein activator like 2 |
| RBM26 | RNA binding motif protein 26 |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RHAG | Rh-associated glycoprotein |
| RNF122 | ring finger protein 122 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
| SFTPB | surfactant protein B |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SMO | smoothened, frizzled class receptor |
| TBC1D30 | TBC1 domain family, member 30 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TUBBP5 | tubulin, beta pseudogene 5 |
| USP22 | ubiquitin specific peptidase 22 |
| WFDC1 | WAP four-disulfide core domain 1 |
| XPNPEP1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZMYM2 | zinc finger, MYM-type 2 |
| ZNF3 | zinc finger protein 3 |
| ZNF613 | zinc finger protein 613 |
| ZNF639 | zinc finger protein 639 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABHD8 | abhydrolase domain containing 8 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| C1S | complement component 1, s subcomponent |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CAPN15 | calpain 15 |
| CBX4 | chromobox homolog 4 |
| CCDC177 | coiled-coil domain containing 177 |
| CCDC9 | coiled-coil domain containing 9 |
| CCNO | cyclin O |
| CFAP45 | cilia and flagella associated protein 45 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CNTN1 | contactin 1 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DEAF1 | DEAF1 transcription factor |
| DOK5 | docking protein 5 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EML4 | echinoderm microtubule associated protein like 4 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FKBP5 | FK506 binding protein 5 |
| FZD10 | frizzled class receptor 10 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLB1L | galactosidase, beta 1-like |
| GMIP | GEM interacting protein |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR21 | G protein-coupled receptor 21 |
| GTF2I | general transcription factor IIi |
| H1F0 | H1 histone family, member 0 |
| IL17RB | interleukin 17 receptor B |
| IL2 | interleukin 2 |
| IL22 | interleukin 22 |
| IL6 | interleukin 6 |
| ITPKA | inositol-trisphosphate 3-kinase A |
| KIAA0319L | KIAA0319-like |
| KIF13A | kinesin family member 13A |
| KLC2 | kinesin light chain 2 |
| KRT6B | keratin 6B, type II |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LRRC61 | leucine rich repeat containing 61 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LY86 | lymphocyte antigen 86 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MUC3B | mucin 3B, cell surface associated |
| MYO1F | myosin IF |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NKX3-2 | NK3 homeobox 2 |
| NOL10 | nucleolar protein 10 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NRTN | neurturin |
| OSBP2 | oxysterol binding protein 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAQR5 | progestin and adipoQ receptor family member V |
| PDE12 | phosphodiesterase 12 |
| PENK | proenkephalin |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAI2 | retinoic acid induced 2 |
| RARS | arginyl-tRNA synthetase |
| RFPL1S | RFPL1 antisense RNA 1 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SETD1A | SET domain containing 1A |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMAD7 | SMAD family member 7 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| STON1 | stonin 1 |
| SYCP2 | synaptonemal complex protein 2 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAOK1 | TAO kinase 1 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TLN1 | talin 1 |
| TNFSF12 | tumor necrosis factor (ligand) superfamily, member 12 |
| TOR4A | torsin family 4, member A |
| TXK | TXK tyrosine kinase |
| VGLL3 | vestigial-like family member 3 |
| XAB2 | XPA binding protein 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZFHX3 | zinc finger homeobox 3 |
| ZNF155 | zinc finger protein 155 |
| ZNF415 | zinc finger protein 415 |
| ZNF446 | zinc finger protein 446 |
