phenylpropanolamine-1602 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the phenylpropanolamine-1602 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALOXE3 arachidonate lipoxygenase 3
AP3S2 adaptor-related protein complex 3, sigma 2 subunit
ASB13 ankyrin repeat and SOCS box containing 13
ASB8 ankyrin repeat and SOCS box containing 8
ASMTL acetylserotonin O-methyltransferase-like
ATG13 autophagy related 13
ATP11A ATPase, class VI, type 11A
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
ATP5SL ATP5S-like
BCAN brevican
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
C1ORF123 chromosome 1 open reading frame 123
C4BPA complement component 4 binding protein, alpha
CANT1 calcium activated nucleotidase 1
CAPRIN2 caprin family member 2
CDCA3 cell division cycle associated 3
CEP72 centrosomal protein 72kDa
CIZ1 CDKN1A interacting zinc finger protein 1
COL10A1 collagen, type X, alpha 1
COQ4 coenzyme Q4
CYB561 cytochrome b561
DCPS decapping enzyme, scavenger
DOK3 docking protein 3
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
FASTK Fas-activated serine/threonine kinase
FPR1 formyl peptide receptor 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GORASP1 golgi reassembly stacking protein 1, 65kDa
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPATCH4 G patch domain containing 4
GRIK5 glutamate receptor, ionotropic, kainate 5
GRK6 G protein-coupled receptor kinase 6
GSK3A glycogen synthase kinase 3 alpha
GSTM5 glutathione S-transferase mu 5
HBS1L HBS1-like translational GTPase
HFE hemochromatosis
HOMER1 homer scaffolding protein 1
HOXD1 homeobox D1
IGFBP7 insulin-like growth factor binding protein 7
INTS9 integrator complex subunit 9
KDM6B lysine (K)-specific demethylase 6B
KIFC1 kinesin family member C1
KLF10 Kruppel-like factor 10
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
MAP2K5 mitogen-activated protein kinase kinase 5
MED1 mediator complex subunit 1
MYOF myoferlin
NCOA3 nuclear receptor coactivator 3
NDRG3 NDRG family member 3
NHEJ1 nonhomologous end-joining factor 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUP205 nucleoporin 205kDa
NXPH3 neurexophilin 3
OGG1 8-oxoguanine DNA glycosylase
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PCYOX1L prenylcysteine oxidase 1 like
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PPP1R10 protein phosphatase 1, regulatory subunit 10
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RABL3 RAB, member of RAS oncogene family-like 3
RARS arginyl-tRNA synthetase
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RECQL4 RecQ protein-like 4
RHOH ras homolog family member H
RHOT2 ras homolog family member T2
RNF141 ring finger protein 141
RWDD3 RWD domain containing 3
SAMM50 SAMM50 sorting and assembly machinery component
SDHAF3 succinate dehydrogenase complex assembly factor 3
SEPHS1 selenophosphate synthetase 1
SIDT2 SID1 transmembrane family, member 2
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC25A40 solute carrier family 25, member 40
SMAD7 SMAD family member 7
SMC2 structural maintenance of chromosomes 2
SMG7 SMG7 nonsense mediated mRNA decay factor
SOS1 son of sevenless homolog 1 (Drosophila)
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SRSF7 serine/arginine-rich splicing factor 7
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
TBCCD1 TBCC domain containing 1
TFCP2L1 transcription factor CP2-like 1
TMEM127 transmembrane protein 127
TMEM39B transmembrane protein 39B
TRAM1 translocation associated membrane protein 1
UNC45A unc-45 homolog A (C. elegans)
USF2 upstream transcription factor 2, c-fos interacting
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZBTB48 zinc finger and BTB domain containing 48
ZC3H14 zinc finger CCCH-type containing 14
ZNF337 zinc finger protein 337
ZSCAN26 zinc finger and SCAN domain containing 26

decreased expression

Symbol Name
AAR2 AAR2 splicing factor homolog (S. cerevisiae)
ANAPC2 anaphase promoting complex subunit 2
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
APOBR apolipoprotein B receptor
ARHGAP4 Rho GTPase activating protein 4
ATAD2B ATPase family, AAA domain containing 2B
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BCCIP BRCA2 and CDKN1A interacting protein
C11ORF68 chromosome 11 open reading frame 68
CALCOCO1 calcium binding and coiled-coil domain 1
CAPN15 calpain 15
CCL4 chemokine (C-C motif) ligand 4
CCNA1 cyclin A1
CD151 CD151 molecule (Raph blood group)
CD82 CD82 molecule
CDT1 chromatin licensing and DNA replication factor 1
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CIC capicua transcriptional repressor
CLTCL1 clathrin, heavy chain-like 1
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
CNTD2 cyclin N-terminal domain containing 2
CRELD2 cysteine-rich with EGF-like domains 2
CRYBB2P1 crystallin, beta B2 pseudogene 1
DBR1 debranching RNA lariats 1
DET1 de-etiolated homolog 1 (Arabidopsis)
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
ERCC2 excision repair cross-complementation group 2
EXD2 exonuclease 3'-5' domain containing 2
FAM117A family with sequence similarity 117, member A
FBRS fibrosin
FBXL14 F-box and leucine-rich repeat protein 14
FBXL4 F-box and leucine-rich repeat protein 4
FGR FGR proto-oncogene, Src family tyrosine kinase
FMNL1 formin-like 1
GMIP GEM interacting protein
GPATCH3 G patch domain containing 3
HOOK2 hook microtubule-tethering protein 2
IFI6 interferon, alpha-inducible protein 6
IRF7 interferon regulatory factor 7
IRF9 interferon regulatory factor 9
KRCC1 lysine-rich coiled-coil 1
LOC729164 hCG1732469
LUC7L LUC7-like (S. cerevisiae)
MAGOHB mago-nashi homolog B (Drosophila)
MAVS mitochondrial antiviral signaling protein
MBIP MAP3K12 binding inhibitory protein 1
MGAM maltase-glucoamylase
MITF microphthalmia-associated transcription factor
MLPH melanophilin
MNAT1 MNAT CDK-activating kinase assembly factor 1
MON1B MON1 secretory trafficking family member B
MYO9A myosin IXA
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit
NOD1 nucleotide-binding oligomerization domain containing 1
NUBP2 nucleotide binding protein 2
NUP93 nucleoporin 93kDa
PCDHGB5 protocadherin gamma subfamily B, 5
PHF21A PHD finger protein 21A
PINK1 PTEN induced putative kinase 1
PODNL1 podocan-like 1
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
RNF11 ring finger protein 11
RRP1 ribosomal RNA processing 1
RUFY2 RUN and FYVE domain containing 2
SCML1 sex comb on midleg-like 1 (Drosophila)
SDC4 syndecan 4
SF3B4 splicing factor 3b, subunit 4, 49kDa
SIRT6 sirtuin 6
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SMC6 structural maintenance of chromosomes 6
STEAP3 STEAP family member 3, metalloreductase
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
TAC3 tachykinin 3
TERF2IP telomeric repeat binding factor 2, interacting protein
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
THAP7 THAP domain containing 7
THBS4 thrombospondin 4
TLN1 talin 1
TM7SF2 transmembrane 7 superfamily member 2
TMEM158 transmembrane protein 158 (gene/pseudogene)
TSPAN14 tetraspanin 14
TUBB3 tubulin, beta 3 class III
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBQLN4 ubiquilin 4
USB1 U6 snRNA biogenesis 1
XAF1 XIAP associated factor 1
XDH xanthine dehydrogenase
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF140 zinc finger protein 140
ZNRD1-AS1 ZNRD1 antisense RNA 1