phenylpropanolamine-5298 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the phenylpropanolamine-5298 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADARB1 adenosine deaminase, RNA-specific, B1
AHNAK2 AHNAK nucleoprotein 2
ALCAM activated leukocyte cell adhesion molecule
APBA3 amyloid beta (A4) precursor protein-binding, family A, member 3
APOC1 apolipoprotein C-I
APOL2 apolipoprotein L, 2
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARL15 ADP-ribosylation factor-like 15
ARTN artemin
ATG2A autophagy related 2A
B9D1 B9 protein domain 1
BAHCC1 BAH domain and coiled-coil containing 1
BAIAP2 BAI1-associated protein 2
BTN2A2 butyrophilin, subfamily 2, member A2
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CDC25C cell division cycle 25C
CEP85 centrosomal protein 85kDa
CHRM3 cholinergic receptor, muscarinic 3
CIC capicua transcriptional repressor
CRABP1 cellular retinoic acid binding protein 1
CRLF1 cytokine receptor-like factor 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
EFNA3 ephrin-A3
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
EIF5A2 eukaryotic translation initiation factor 5A2
EML2 echinoderm microtubule associated protein like 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ESR1 estrogen receptor 1
EXTL3 exostosin-like glycosyltransferase 3
FSCN1 fascin actin-bundling protein 1
GEM GTP binding protein overexpressed in skeletal muscle
GLRX glutaredoxin (thioltransferase)
GLRX3 glutaredoxin 3
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSAP gamma-secretase activating protein
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HFE hemochromatosis
HIST1H2AJ histone cluster 1, H2aj
HLA-F major histocompatibility complex, class I, F
HPN hepsin
INHBA inhibin, beta A
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KIF5C kinesin family member 5C
LMNA lamin A/C
LRP12 low density lipoprotein receptor-related protein 12
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYST lysosomal trafficking regulator
MAN1A1 mannosidase, alpha, class 1A, member 1
MAP1A microtubule-associated protein 1A
MBD1 methyl-CpG binding domain protein 1
MED16 mediator complex subunit 16
MTA2 metastasis associated 1 family, member 2
MVP major vault protein
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NCAPH2 non-SMC condensin II complex, subunit H2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NRF1 nuclear respiratory factor 1
NRGN neurogranin (protein kinase C substrate, RC3)
OLFML2A olfactomedin-like 2A
OSBPL2 oxysterol binding protein-like 2
PAWR PRKC, apoptosis, WT1, regulator
PCDHB3 protocadherin beta 3
PDAP1 PDGFA associated protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PIAS4 protein inhibitor of activated STAT, 4
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PTRF polymerase I and transcript release factor
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
RAB3A RAB3A, member RAS oncogene family
RABGAP1L RAB GTPase activating protein 1-like
RBBP9 retinoblastoma binding protein 9
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNF2 ring finger protein 2
RPGR retinitis pigmentosa GTPase regulator
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
RTEL1 regulator of telomere elongation helicase 1
RUNDC3B RUN domain containing 3B
S100A4 S100 calcium binding protein A4
S100A9 S100 calcium binding protein A9
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERGEF secretion regulating guanine nucleotide exchange factor
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SNW1 SNW domain containing 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STX2 syntaxin 2
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAS2R10 taste receptor, type 2, member 10
TM2D1 TM2 domain containing 1
TMSB15A thymosin beta 15a
UTRN utrophin
VCAN versican
ZFPL1 zinc finger protein-like 1
ZNF696 zinc finger protein 696
ZNF79 zinc finger protein 79

decreased expression

Symbol Name
ACTR3B ARP3 actin-related protein 3 homolog B (yeast)
ADAM15 ADAM metallopeptidase domain 15
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BBS7 Bardet-Biedl syndrome 7
BPGM 2,3-bisphosphoglycerate mutase
CCNT1 cyclin T1
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHPF chondroitin polymerizing factor
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COPS7B COP9 signalosome subunit 7B
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DHRS7B dehydrogenase/reductase (SDR family) member 7B
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAAF2 dynein, axonemal, assembly factor 2
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DVL1 dishevelled segment polarity protein 1
EGR3 early growth response 3
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM63A family with sequence similarity 63, member A
FBRS fibrosin
FBXL4 F-box and leucine-rich repeat protein 4
FEM1C fem-1 homolog c (C. elegans)
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GLI3 GLI family zinc finger 3
HIST1H1D histone cluster 1, H1d
HOOK1 hook microtubule-tethering protein 1
HOXA5 homeobox A5
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI6 interferon, alpha-inducible protein 6
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
INPP5K inositol polyphosphate-5-phosphatase K
IREB2 iron-responsive element binding protein 2
JADE3 jade family PHD finger 3
KDM5C lysine (K)-specific demethylase 5C
KIAA0430 KIAA0430
KLC2 kinesin light chain 2
LINC00115 long intergenic non-protein coding RNA 115
LINS lines homolog (Drosophila)
LMNB1 lamin B1
MAGEH1 melanoma antigen family H1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
METTL8 methyltransferase like 8
MMP9 matrix metallopeptidase 9
NCS1 neuronal calcium sensor 1
NECAP2 NECAP endocytosis associated 2
NNT nicotinamide nucleotide transhydrogenase
NPM3 nucleophosmin/nucleoplasmin 3
NPY1R neuropeptide Y receptor Y1
NUPL2 nucleoporin like 2
OLFML3 olfactomedin-like 3
PARD6A par-6 family cell polarity regulator alpha
PCF11 PCF11 cleavage and polyadenylation factor subunit
PCSK7 proprotein convertase subtilisin/kexin type 7
PLEKHO1 pleckstrin homology domain containing, family O member 1
POMZP3 POM121 and ZP3 fusion
POR P450 (cytochrome) oxidoreductase
PRICKLE3 prickle homolog 3 (Drosophila)
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRMT7 protein arginine methyltransferase 7
PROS1 protein S (alpha)
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RBM15B RNA binding motif protein 15B
RBM42 RNA binding motif protein 42
RFTN1 raftlin, lipid raft linker 1
RIC8B RIC8 guanine nucleotide exchange factor B
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SAMHD1 SAM domain and HD domain 1
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH3GL1 SH3-domain GRB2-like 1
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMAGP small cell adhesion glycoprotein
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SND1-IT1 SND1 intronic transcript 1
SNX15 sorting nexin 15
SSBP3 single stranded DNA binding protein 3
SSFA2 sperm specific antigen 2
STBD1 starch binding domain 1
STK16 serine/threonine kinase 16
SUSD6 sushi domain containing 6
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAGLN transgelin
TEX264 testis expressed 264
TMED1 transmembrane emp24 protein transport domain containing 1
TRABD TraB domain containing
TSKU tsukushi, small leucine rich proteoglycan
TULP4 tubby like protein 4
UBQLN4 ubiquilin 4
VGF VGF nerve growth factor inducible
VWA1 von Willebrand factor A domain containing 1
ZBED1 zinc finger, BED-type containing 1
ZBTB38 zinc finger and BTB domain containing 38
ZFHX3 zinc finger homeobox 3
ZNF211 zinc finger protein 211
ZNF394 zinc finger protein 394
ZNF580 zinc finger protein 580
ZNF668 zinc finger protein 668