phosphate regulating endopeptidase homolog, X-linked|The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013] (NCBI Entrez Gene Database, 5251)
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9 genes co-occuring with the biological term phex in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
