phf8 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description PHD finger protein 8|The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 23133)
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Genes

8 genes co-occuring with the biological term phf8 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
CDC20 cell division cycle 20
FAM120C family with sequence similarity 120C
MIR21 microRNA 21
PHF2 PHD finger protein 2
PHF8 PHD finger protein 8
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
WNK3 WNK lysine deficient protein kinase 3
ZNF711 zinc finger protein 711