phosphatidylinositol-3,4,5-trisphosphate binding Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions. (Gene Ontology, GO_0005547)
External Link http://amigo.geneontology.org/amigo/term/GO:0005547
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Genes

38 genes performing the phosphatidylinositol-3,4,5-trisphosphate binding molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
ADAP2 ArfGAP with dual PH domains 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANXA8L1 annexin A8-like 1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGAP9 Rho GTPase activating protein 9
BTK Bruton agammaglobulinemia tyrosine kinase
COMMD1 copper metabolism (Murr1) domain containing 1
CYTH3 cytohesin 3
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DNM1 dynamin 1
FCHSD2 FCH and double SH3 domains 2
FERMT2 fermitin family member 2
FUNDC2 FUN14 domain containing 2
GAB2 GRB2-associated binding protein 2
HIP1R huntingtin interacting protein 1 related
IQGAP1 IQ motif containing GTPase activating protein 1
IQGAP2 IQ motif containing GTPase activating protein 2
JPH2 junctophilin 2
KIF16B kinesin family member 16B
MAPKAP1 mitogen-activated protein kinase associated protein 1
MYO10 myosin X
MYO1B myosin IB
MYO1G myosin IG
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PARD3 par-3 family cell polarity regulator
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLA2G4E phospholipase A2, group IVE
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
PTGES2 prostaglandin E synthase 2
RACGAP1 Rac GTPase activating protein 1
RAG2 recombination activating gene 2
WASHC2C WASH complex subunit 2C
ZFYVE1 zinc finger, FYVE domain containing 1
ZFYVE16 zinc finger, FYVE domain containing 16