phospholipase activity Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Catalysis of the hydrolysis of a glycerophospholipid. (Gene Ontology, GO_0004620)
External Link http://amigo.geneontology.org/amigo/term/GO:0004620
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Genes

84 genes performing the phospholipase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
ABHD12 abhydrolase domain containing 12
ABHD12B abhydrolase domain containing 12B
ABHD16A abhydrolase domain containing 16A
ABHD16B abhydrolase domain containing 16B
ABHD3 abhydrolase domain containing 3
ABHD4 abhydrolase domain containing 4
ASPG asparaginase
CLCF1 cardiotrophin-like cytokine factor 1
DDHD1 DDHD domain containing 1
DDHD2 DDHD domain containing 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
GDE1 glycerophosphodiester phosphodiesterase 1
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
LGALS13 lectin, galactoside-binding, soluble, 13
LIPC lipase, hepatic
LIPG lipase, endothelial
LIPH lipase, member H
LIPI lipase, member I
LPL lipoprotein lipase
LYPLA1 lysophospholipase I
LYPLA2 lysophospholipase II
LYPLAL1 lysophospholipase-like 1
MGLL monoglyceride lipase
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D
NOTUM notum pectinacetylesterase homolog (Drosophila)
PDIA3 protein disulfide isomerase family A, member 3
PITPNM3 PITPNM family member 3
PLA1A phospholipase A1 member A
PLA2G10 phospholipase A2, group X
PLA2G12A phospholipase A2, group XIIA
PLA2G15 phospholipase A2, group XV
PLA2G1B phospholipase A2, group IB (pancreas)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G2D phospholipase A2, group IID
PLA2G2E phospholipase A2, group IIE
PLA2G2F phospholipase A2, group IIF
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G4B phospholipase A2, group IVB (cytosolic)
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLA2G4D phospholipase A2, group IVD (cytosolic)
PLA2G4E phospholipase A2, group IVE
PLA2G4F phospholipase A2, group IVF
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAAT1 phospholipase A and acyltransferase 1
PLAAT2 phospholipase A and acyltransferase 2
PLAAT3 phospholipase A and acyltransferase 3
PLAAT4 phospholipase A and acyltransferase 4
PLAAT5 phospholipase A and acyltransferase 5
PLB1 phospholipase B1
PLBD1 phospholipase B domain containing 1
PLBD2 phospholipase B domain containing 2
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLCB2 phospholipase C, beta 2
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCB4 phospholipase C, beta 4
PLCE1 phospholipase C, epsilon 1
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCL1 phospholipase C-like 1
PLD2 phospholipase D2
PLD3 phospholipase D family, member 3
PLD4 phospholipase D family, member 4
PLD6 phospholipase D family, member 6
PNLIP pancreatic lipase
PNLIPRP1 pancreatic lipase-related protein 1
PNLIPRP2 pancreatic lipase-related protein 2
PNLIPRP3 pancreatic lipase-related protein 3
PNPLA2 patatin-like phospholipase domain containing 2
PNPLA3 patatin-like phospholipase domain containing 3
PNPLA4 patatin-like phospholipase domain containing 4
PNPLA6 patatin-like phospholipase domain containing 6
PNPLA7 patatin-like phospholipase domain containing 7
PRDX5 peroxiredoxin 5
PRKCSH protein kinase C substrate 80K-H
SACK1B scaffolding CK1 anchoring protein B
SEC23IP SEC23 interacting protein
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A