phthalylsulfathiazole-4653 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the phthalylsulfathiazole-4653 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ADAM11 ADAM metallopeptidase domain 11
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGB androglobin
AGFG2 ArfGAP with FG repeats 2
AIM2 absent in melanoma 2
ALDOB aldolase B, fructose-bisphosphate
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
APOB apolipoprotein B
C1QL1 complement component 1, q subcomponent-like 1
C9ORF156 chromosome 9 open reading frame 156
CAMTA1 calmodulin binding transcription activator 1
CD1C CD1c molecule
CD28 CD28 molecule
CDH10 cadherin 10, type 2 (T2-cadherin)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLTCL1 clathrin, heavy chain-like 1
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COL9A3 collagen, type IX, alpha 3
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
E2F2 E2F transcription factor 2
ENG endoglin
EXOSC1 exosome component 1
FCAR Fc fragment of IgA receptor
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGF20 fibroblast growth factor 20
FRMD4B FERM domain containing 4B
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GALR3 galanin receptor 3
GLP1R glucagon-like peptide 1 receptor
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GPSM3 G-protein signaling modulator 3
GYPB glycophorin B (MNS blood group)
HABP4 hyaluronan binding protein 4
HES2 hes family bHLH transcription factor 2
HFE hemochromatosis
HGFAC HGF activator
HOXD13 homeobox D13
HPCA hippocalcin
IFNA8 interferon, alpha 8
IGL immunoglobulin lambda locus
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL19 interleukin 19
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KL klotho
KLHDC8A kelch domain containing 8A
KLK3 kallikrein-related peptidase 3
KRTAP5-9 keratin associated protein 5-9
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LOC100131532 uncharacterized LOC100131532
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAGEB4 melanoma antigen family B4
MAP2 microtubule-associated protein 2
MASP2 mannan-binding lectin serine peptidase 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MOBP myelin-associated oligodendrocyte basic protein
MRAS muscle RAS oncogene homolog
MUC4 mucin 4, cell surface associated
MUC6 mucin 6, oligomeric mucus/gel-forming
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NCR2 natural cytotoxicity triggering receptor 2
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NOX1 NADPH oxidase 1
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR4A1 nuclear receptor subfamily 4, group A, member 1
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
OCM2 oncomodulin 2
PARP8 poly (ADP-ribose) polymerase family, member 8
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PMFBP1 polyamine modulated factor 1 binding protein 1
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRB4 proline-rich protein BstNI subfamily 4
PRDM12 PR domain containing 12
PRKCE protein kinase C, epsilon
PSG9 pregnancy specific beta-1-glycoprotein 9
PYY peptide YY
RBM12B RNA binding motif protein 12B
RGS6 regulator of G-protein signaling 6
RIN3 Ras and Rab interactor 3
SLA Src-like-adaptor
SOX10 SRY (sex determining region Y)-box 10
SRPK3 SRSF protein kinase 3
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
TCP11L1 t-complex 11, testis-specific-like 1
TIMP3 TIMP metallopeptidase inhibitor 3
WNT8B wingless-type MMTV integration site family, member 8B
ZBTB7A zinc finger and BTB domain containing 7A
ZCCHC14 zinc finger, CCHC domain containing 14
ZNF208 zinc finger protein 208
ZNF223 zinc finger protein 223
ZNF814 zinc finger protein 814
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABHD17B abhydrolase domain containing 17B
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADCY6 adenylate cyclase 6
AFAP1 actin filament associated protein 1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
BAK1 BCL2-antagonist/killer 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C1RL complement component 1, r subcomponent-like
C4ORF29 chromosome 4 open reading frame 29
CCNO cyclin O
CDT1 chromatin licensing and DNA replication factor 1
CFAP44 cilia and flagella associated protein 44
CHCHD7 coiled-coil-helix-coiled-coil-helix domain containing 7
CHMP1A charged multivesicular body protein 1A
CLDN15 claudin 15
CLDND1 claudin domain containing 1
CRELD1 cysteine-rich with EGF-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DENND4A DENN/MADD domain containing 4A
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EML4 echinoderm microtubule associated protein like 4
EXOC5 exocyst complex component 5
FAM120C family with sequence similarity 120C
FUZ fuzzy planar cell polarity protein
GLRB glycine receptor, beta
GLT8D2 glycosyltransferase 8 domain containing 2
GMEB1 glucocorticoid modulatory element binding protein 1
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNL1 guanine nucleotide binding protein-like 1
GPR176 G protein-coupled receptor 176
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HMOX1 heme oxygenase 1
HOMER2 homer scaffolding protein 2
HOXA1 homeobox A1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IPO8 importin 8
KDM4D lysine (K)-specific demethylase 4D
KLF2 Kruppel-like factor 2
KLF3 Kruppel-like factor 3 (basic)
KLF7 Kruppel-like factor 7 (ubiquitous)
LHFPL2 lipoma HMGIC fusion partner-like 2
LIG4 ligase IV, DNA, ATP-dependent
LPAR3 lysophosphatidic acid receptor 3
MED15 mediator complex subunit 15
MFGE8 milk fat globule-EGF factor 8 protein
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NDP Norrie disease (pseudoglioma)
OSMR oncostatin M receptor
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PALMD palmdelphin
PARP3 poly (ADP-ribose) polymerase family, member 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLEKHO1 pleckstrin homology domain containing, family O member 1
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK6 protein tyrosine kinase 6
PUS1 pseudouridylate synthase 1
RBM38 RNA binding motif protein 38
RIN1 Ras and Rab interactor 1
ROM1 retinal outer segment membrane protein 1
SCHIP1 schwannomin interacting protein 1
SCRN3 secernin 3
SETD6 SET domain containing 6
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SMAD5 SMAD family member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNIP1 Smad nuclear interacting protein 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SYNC syncoilin, intermediate filament protein
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TCTN1 tectonic family member 1
TEX40 testis expressed 40
TMEM121 transmembrane protein 121
TMEM132A transmembrane protein 132A
TMEM53 transmembrane protein 53
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM25 tripartite motif containing 25
TSKU tsukushi, small leucine rich proteoglycan
UGT8 UDP glycosyltransferase 8
WDR19 WD repeat domain 19
YY2 YY2 transcription factor
ZBTB39 zinc finger and BTB domain containing 39
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF10 zinc finger protein 10
ZNF137P zinc finger protein 137, pseudogene
ZNF276 zinc finger protein 276
ZNF711 zinc finger protein 711
ZNF76 zinc finger protein 76