phthalylsulfathiazole-5614 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the phthalylsulfathiazole-5614 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM29 ADAM metallopeptidase domain 29
AIF1 allograft inflammatory factor 1
ALDOAP2 aldolase A, fructose-bisphosphate pseudogene 2
ANGPTL2 angiopoietin-like 2
ARHGAP33 Rho GTPase activating protein 33
ART1 ADP-ribosyltransferase 1
ASIC1 acid sensing (proton gated) ion channel 1
ASIC4 acid sensing (proton gated) ion channel family member 4
ATP10A ATPase, class V, type 10A
BAAT bile acid CoA:amino acid N-acyltransferase
BTN3A3 butyrophilin, subfamily 3, member A3
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CCDC64 coiled-coil domain containing 64
CD200 CD200 molecule
CD52 CD52 molecule
CD86 CD86 molecule
CELA3A chymotrypsin-like elastase family, member 3A
CFAP69 cilia and flagella associated protein 69
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CPEB3 cytoplasmic polyadenylation element binding protein 3
CST4 cystatin S
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DPF1 D4, zinc and double PHD fingers family 1
DTNB dystrobrevin, beta
EDA ectodysplasin A
EPYC epiphycan
EVA1B eva-1 homolog B (C. elegans)
F13A1 coagulation factor XIII, A1 polypeptide
FAM163A family with sequence similarity 163, member A
FAM182B family with sequence similarity 182, member B
FGF13 fibroblast growth factor 13
FGFBP1 fibroblast growth factor binding protein 1
FLJ11710 uncharacterized protein FLJ11710
FSCN1 fascin actin-bundling protein 1
FZD9 frizzled class receptor 9
GAB1 GRB2-associated binding protein 1
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HIF3A hypoxia inducible factor 3, alpha subunit
HOXB5 homeobox B5
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IDUA iduronidase, alpha-L-
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNIP1 Kv channel interacting protein 1
KLRB1 killer cell lectin-like receptor subfamily B, member 1
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KRT75 keratin 75, type II
LAMP1 lysosomal-associated membrane protein 1
LAPTM5 lysosomal protein transmembrane 5
LARP6 La ribonucleoprotein domain family, member 6
LGALS2 lectin, galactoside-binding, soluble, 2
LHX1 LIM homeobox 1
LMF2 lipase maturation factor 2
LSP1 lymphocyte-specific protein 1
MAPK10 mitogen-activated protein kinase 10
MARK4 MAP/microtubule affinity-regulating kinase 4
MC5R melanocortin 5 receptor
MIER2 mesoderm induction early response 1, family member 2
MIP major intrinsic protein of lens fiber
MON2 MON2 homolog (S. cerevisiae)
MSN moesin
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYOZ3 myozenin 3
NOVA1 neuro-oncological ventral antigen 1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NRF1 nuclear respiratory factor 1
PHF14 PHD finger protein 14
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLCB2 phospholipase C, beta 2
PLCD1 phospholipase C, delta 1
PLSCR2 phospholipid scramblase 2
PML promyelocytic leukemia
RAB33A RAB33A, member RAS oncogene family
RARB retinoic acid receptor, beta
RDH16 retinol dehydrogenase 16 (all-trans)
RIMS2 regulating synaptic membrane exocytosis 2
RND2 Rho family GTPase 2
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A8 S100 calcium binding protein A8
SFRP4 secreted frizzled-related protein 4
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOX21 SRY (sex determining region Y)-box 21
SRPK3 SRSF protein kinase 3
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
STK11 serine/threonine kinase 11
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYT11 synaptotagmin XI
TBXA2R thromboxane A2 receptor
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRAF3IP3 TRAF3 interacting protein 3
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
VCX2 variable charge, X-linked 2
WSCD1 WSC domain containing 1
ZNF536 zinc finger protein 536

decreased expression

Symbol Name
ACTL8 actin-like 8
ASAP1-IT1 ASAP1 intronic transcript 1
ATAT1 alpha tubulin acetyltransferase 1
BIK BCL2-interacting killer (apoptosis-inducing)
C11ORF63 chromosome 11 open reading frame 63
C2ORF27A chromosome 2 open reading frame 27A
C7ORF43 chromosome 7 open reading frame 43
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC186 coiled-coil domain containing 186
CCDC94 coiled-coil domain containing 94
CCNL2 cyclin L2
CDADC1 cytidine and dCMP deaminase domain containing 1
CENPO centromere protein O
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIDEC cell death-inducing DFFA-like effector c
CLCF1 cardiotrophin-like cytokine factor 1
CLK1 CDC-like kinase 1
CLSTN2 calsyntenin 2
CRY2 cryptochrome circadian clock 2
DDIT3 DNA-damage-inducible transcript 3
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EPN1 epsin 1
FAM110B family with sequence similarity 110, member B
FAM155A family with sequence similarity 155, member A
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAMT guanidinoacetate N-methyltransferase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GFI1 growth factor independent 1 transcription repressor
GMIP GEM interacting protein
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GRPR gastrin-releasing peptide receptor
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H2AM histone cluster 1, H2am
HOXB2 homeobox B2
HOXC4 homeobox C4
HP1BP3 heterochromatin protein 1, binding protein 3
IFT140 intraflagellar transport 140
IL2 interleukin 2
LINC00597 long intergenic non-protein coding RNA 597
LOC100286895 cell division cycle 27 homolog pseudogene
LOXL3 lysyl oxidase-like 3
LRP5L low density lipoprotein receptor-related protein 5-like
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MORC3 MORC family CW-type zinc finger 3
NCALD neurocalcin delta
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NME5 NME/NM23 family member 5
NT5E 5'-nucleotidase, ecto (CD73)
OLFML2A olfactomedin-like 2A
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
OVOL1 ovo-like zinc finger 1
PACS1 phosphofurin acidic cluster sorting protein 1
PARD6B par-6 family cell polarity regulator beta
PHC1 polyhomeotic homolog 1 (Drosophila)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLD2 phospholipase D2
POU4F2 POU class 4 homeobox 2
PRPH peripherin
PRR4 proline rich 4 (lacrimal)
PRSS53 protease, serine, 53
PVRL3 poliovirus receptor-related 3
QSER1 glutamine and serine rich 1
RAB36 RAB36, member RAS oncogene family
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFXAP regulatory factor X-associated protein
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF39 ring finger protein 39
RPL10L ribosomal protein L10-like
RPL23AP32 ribosomal protein L23a pseudogene 32
S100A7 S100 calcium binding protein A7
SDC3 syndecan 3
SETD1A SET domain containing 1A
SKA1 spindle and kinetochore associated complex subunit 1
SLC22A14 solute carrier family 22, member 14
SMIM14 small integral membrane protein 14
SSTR4 somatostatin receptor 4
ST5 suppression of tumorigenicity 5
TBC1D17 TBC1 domain family, member 17
TBC1D19 TBC1 domain family, member 19
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCHH trichohyalin
TM6SF1 transmembrane 6 superfamily member 1
TMEM45A transmembrane protein 45A
TMEM62 transmembrane protein 62
TSPAN5 tetraspanin 5
TTLL1 tubulin tyrosine ligase-like family member 1
UPP1 uridine phosphorylase 1
VASP vasodilator-stimulated phosphoprotein
ZBTB22 zinc finger and BTB domain containing 22
ZBTB44 zinc finger and BTB domain containing 44
ZNF205 zinc finger protein 205
ZNF432 zinc finger protein 432
ZNF573 zinc finger protein 573
ZNF711 zinc finger protein 711
ZNF747 zinc finger protein 747