physiologic Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

206 genes co-occuring with the biological term physiologic in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ADAM17 ADAM metallopeptidase domain 17
ADRB2 adrenoceptor beta 2, surface
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AICDA activation-induced cytidine deaminase
ALPL alkaline phosphatase, liver/bone/kidney
AMH anti-Mullerian hormone
ANG angiogenin, ribonuclease, RNase A family, 5
ANGPT2 angiopoietin 2
APOB apolipoprotein B
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
AQP8 aquaporin 8
ATM ATM serine/threonine kinase
AURKA aurora kinase A
B2M beta-2-microglobulin
BAX BCL2-associated X protein
BLVRA biliverdin reductase A
BRAF B-Raf proto-oncogene, serine/threonine kinase
BSG basigin (Ok blood group)
BTG2 BTG family, member 2
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CCL20 chemokine (C-C motif) ligand 20
CCND1 cyclin D1
CCNE1 cyclin E1
CCR2 chemokine (C-C motif) receptor 2
CD177 CD177 molecule
CD19 CD19 molecule
CD200 CD200 molecule
CD34 CD34 molecule
CD44 CD44 molecule (Indian blood group)
CD99 CD99 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHGA chromogranin A
CLCN1 chloride channel, voltage-sensitive 1
CLDN4 claudin 4
CLIC1 chloride intracellular channel 1
COMT catechol-O-methyltransferase
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTSG cathepsin G
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DKK1 dickkopf WNT signaling pathway inhibitor 1
DSC2 desmocollin 2
EGFR epidermal growth factor receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
F2 coagulation factor II (thrombin)
F9 coagulation factor IX
FASLG Fas ligand (TNF superfamily, member 6)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FGG fibrinogen gamma chain
FLT3 fms-related tyrosine kinase 3
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GATA3 GATA binding protein 3
GCG glucagon
GDF15 growth differentiation factor 15
GIP gastric inhibitory polypeptide
GLG1 golgi glycoprotein 1
GP6 glycoprotein VI (platelet)
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAMP hepcidin antimicrobial peptide
HCRT hypocretin (orexin) neuropeptide precursor
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGA2 high mobility group AT-hook 2
HNF1A HNF1 homeobox A
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2)
HP haptoglobin
ICAM1 intercellular adhesion molecule 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGF2R insulin-like growth factor 2 receptor
IGFBP3 insulin-like growth factor binding protein 3
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL24 interleukin 24
IL4R interleukin 4 receptor
IL6 interleukin 6
ILF3 interleukin enhancer binding factor 3, 90kDa
IP6K2 inositol hexakisphosphate kinase 2
ISG15 ISG15 ubiquitin-like modifier
ITGA6 integrin, alpha 6
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB3BP integrin beta 3 binding protein (beta3-endonexin)
ITSN2 intersectin 2
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10
KHK ketohexokinase (fructokinase)
KLF15 Kruppel-like factor 15
KLF6 Kruppel-like factor 6
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LEP leptin
LRP5 low density lipoprotein receptor-related protein 5
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MCHR1 melanin-concentrating hormone receptor 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEPE matrix extracellular phosphoglycoprotein
MFRP membrane frizzled-related protein
MOCS3 molybdenum cofactor synthesis 3
MSMB microseminoprotein, beta-
MTA1 metastasis associated 1
MTA3 metastasis associated 1 family, member 3
MTM1 myotubularin 1
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NCOA3 nuclear receptor coactivator 3
NEU1 sialidase 1 (lysosomal sialidase)
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NOTCH2 notch 2
NPY neuropeptide Y
NQO1 NAD(P)H dehydrogenase, quinone 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRG1 neuregulin 1
NTN4 netrin 4
NUP214 nucleoporin 214kDa
OPRM1 opioid receptor, mu 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PCSK9 proprotein convertase subtilisin/kexin type 9
PDE5A phosphodiesterase 5A, cGMP-specific
PDYN prodynorphin
PINK1 PTEN induced putative kinase 1
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PML promyelocytic leukemia
PMP22 peripheral myelin protein 22
PPARG peroxisome proliferator-activated receptor gamma
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP1R8 protein phosphatase 1, regulatory subunit 8
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROS1 protein S (alpha)
PTAFR platelet-activating factor receptor
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTX3 pentraxin 3, long
PXDN peroxidasin
PYY peptide YY
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RARA retinoic acid receptor, alpha
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBP4 retinol binding protein 4, plasma
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RLN2 relaxin 2
RUNX2 runt-related transcription factor 2
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCN9A sodium channel, voltage gated, type IX alpha subunit
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SELPLG selectin P ligand
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SERPINA10 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SET SET nuclear proto-oncogene
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
SLC40A1 solute carrier family 40 (iron-regulated transporter), member 1
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
SLURP1 secreted LY6/PLAUR domain containing 1
SOST sclerostin
SPP1 secreted phosphoprotein 1
STAU1 staufen double-stranded RNA binding protein 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TARDBP TAR DNA binding protein
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGFA transforming growth factor, alpha
THRA thyroid hormone receptor, alpha
THRB thyroid hormone receptor, beta
TLX3 T-cell leukemia homeobox 3
TNF tumor necrosis factor
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor
WFS1 Wolfram syndrome 1 (wolframin)
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta