| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the physostigmine-1776 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAA2 | acetyl-CoA acyltransferase 2 |
| ACACB | acetyl-CoA carboxylase beta |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ANK2 | ankyrin 2, neuronal |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APOC1 | apolipoprotein C-I |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATP5G2 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) |
| BCAS3 | breast carcinoma amplified sequence 3 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CACYBP | calcyclin binding protein |
| CARD9 | caspase recruitment domain family, member 9 |
| CBX6 | chromobox homolog 6 |
| CCDC40 | coiled-coil domain containing 40 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CHAF1A | chromatin assembly factor 1, subunit A (p150) |
| CLCA1 | chloride channel accessory 1 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLTA | clathrin, light chain A |
| CLTCL1 | clathrin, heavy chain-like 1 |
| COL9A2 | collagen, type IX, alpha 2 |
| CRTAC1 | cartilage acidic protein 1 |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| DST | dystonin |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| EDAR | ectodysplasin A receptor |
| EGR4 | early growth response 4 |
| EHD1 | EH-domain containing 1 |
| EML2 | echinoderm microtubule associated protein like 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| FANCA | Fanconi anemia, complementation group A |
| FGL1 | fibrinogen-like 1 |
| FNTB | farnesyltransferase, CAAX box, beta |
| FRMD8 | FERM domain containing 8 |
| FST | follistatin |
| GRPR | gastrin-releasing peptide receptor |
| GSK3A | glycogen synthase kinase 3 alpha |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| GYPB | glycophorin B (MNS blood group) |
| HEXA | hexosaminidase A (alpha polypeptide) |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HSPB6 | heat shock protein, alpha-crystallin-related, B6 |
| HTRA1 | HtrA serine peptidase 1 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IFNA14 | interferon, alpha 14 |
| INO80D | INO80 complex subunit D |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| KSR1 | kinase suppressor of ras 1 |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LDOC1 | leucine zipper, down-regulated in cancer 1 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAOA | monoamine oxidase A |
| MBD2 | methyl-CpG binding domain protein 2 |
| METTL7A | methyltransferase like 7A |
| MTA1 | metastasis associated 1 |
| NADK | NAD kinase |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NPPA | natriuretic peptide A |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| NUCB1 | nucleobindin 1 |
| NXPH3 | neurexophilin 3 |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PALM | paralemmin |
| PARG | poly (ADP-ribose) glycohydrolase |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PDE8B | phosphodiesterase 8B |
| PSEN2 | presenilin 2 |
| RAB15 | RAB15, member RAS oncogene family |
| RHAG | Rh-associated glycoprotein |
| RPL14 | ribosomal protein L14 |
| SAG | S-antigen; retina and pineal gland (arrestin) |
| SCD5 | stearoyl-CoA desaturase 5 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SFTPB | surfactant protein B |
| SH2D1A | SH2 domain containing 1A |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMAD3 | SMAD family member 3 |
| SNTA1 | syntrophin, alpha 1 |
| SPAG9 | sperm associated antigen 9 |
| STAP2 | signal transducing adaptor family member 2 |
| TCAF1 | TRPM8 channel-associated factor 1 |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TEFM | transcription elongation factor, mitochondrial |
| TGM5 | transglutaminase 5 |
| THBS3 | thrombospondin 3 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRBC1 | T cell receptor beta constant 1 |
| TREX1 | three prime repair exonuclease 1 |
| TRIM29 | tripartite motif containing 29 |
| TSC22D3 | TSC22 domain family, member 3 |
| Symbol | Name |
|---|---|
| AATF | apoptosis antagonizing transcription factor |
| ADM | adrenomedullin |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| APEH | acylaminoacyl-peptide hydrolase |
| APOBR | apolipoprotein B receptor |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| ATF1 | activating transcription factor 1 |
| ATP5J | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 |
| B3GNT1 | |
| BBC3 | BCL2 binding component 3 |
| BCL2L2 | BCL2-like 2 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CD9 | CD9 molecule |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 |
| CEP83 | centrosomal protein 83kDa |
| CIDEB | cell death-inducing DFFA-like effector b |
| CISH | cytokine inducible SH2-containing protein |
| CLDND1 | claudin domain containing 1 |
| COMMD8 | COMM domain containing 8 |
| COQ6 | coenzyme Q6 monooxygenase |
| CPOX | coproporphyrinogen oxidase |
| CYB5R4 | cytochrome b5 reductase 4 |
| DENND4A | DENN/MADD domain containing 4A |
| DIXDC1 | DIX domain containing 1 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DROSHA | drosha, ribonuclease type III |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| FAM46A | family with sequence similarity 46, member A |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FLCN | folliculin |
| GMCL1 | germ cell-less, spermatogenesis associated 1 |
| GOLPH3L | golgi phosphoprotein 3-like |
| GPN3 | GPN-loop GTPase 3 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HINFP | histone H4 transcription factor |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
| HS1BP3 | HCLS1 binding protein 3 |
| KIAA0894 | KIAA0894 protein |
| KTN1 | kinectin 1 (kinesin receptor) |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MCM10 | minichromosome maintenance complex component 10 |
| MIS18BP1 | MIS18 binding protein 1 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MSRB1 | methionine sulfoxide reductase B1 |
| MTERF1 | mitochondrial transcription termination factor 1 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
| NCAPH | non-SMC condensin I complex, subunit H |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NSF | N-ethylmaleimide-sensitive factor |
| NUCLEOLIN | nucleolin multifunctional protein |
| NUP93 | nucleoporin 93kDa |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 |
| PAQR3 | progestin and adipoQ receptor family member III |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
| PCNA | proliferating cell nuclear antigen |
| PCTP | phosphatidylcholine transfer protein |
| PEF1 | penta-EF-hand domain containing 1 |
| PEPD | peptidase D |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha |
| PLCD1 | phospholipase C, delta 1 |
| POLR2F | polymerase (RNA) II (DNA directed) polypeptide F |
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme |
| REPIN1 | replication initiator 1 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RFWD3 | ring finger and WD repeat domain 3 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SEC61G | Sec61 gamma subunit |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SNX6 | sorting nexin 6 |
| STAU2 | staufen double-stranded RNA binding protein 2 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF12 | TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa |
| TCERG1 | transcription elongation regulator 1 |
| TCTN2 | tectonic family member 2 |
| TFB2M | transcription factor B2, mitochondrial |
| TGIF1 | TGFB-induced factor homeobox 1 |
| THOC6 | THO complex 6 |
| TMEM135 | transmembrane protein 135 |
| TMEM53 | transmembrane protein 53 |
| TNRC6B | trinucleotide repeat containing 6B |
| TRHDE | thyrotropin-releasing hormone degrading enzyme |
| TTBK2 | tau tubulin kinase 2 |
| UBQLN4 | ubiquilin 4 |
| UPB1 | ureidopropionase, beta |
| WDR82 | WD repeat domain 82 |
| YEATS4 | YEATS domain containing 4 |
| YTHDF2 | YTH N(6)-methyladenosine RNA binding protein 2 |
| ZNF273 | zinc finger protein 273 |
| ZNF426 | zinc finger protein 426 |
| ZNF432 | zinc finger protein 432 |
