| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the physostigmine-2768 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A4GNT | alpha-1,4-N-acetylglucosaminyltransferase |
| ACAN | aggrecan |
| ADAM8 | ADAM metallopeptidase domain 8 |
| AIM2 | absent in melanoma 2 |
| AK1 | adenylate kinase 1 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APOC1 | apolipoprotein C-I |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BAIAP3 | BAI1-associated protein 3 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CCDC134 | coiled-coil domain containing 134 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
| CES3 | carboxylesterase 3 |
| CLCA1 | chloride channel accessory 1 |
| COL11A1 | collagen, type XI, alpha 1 |
| CSNK1E | casein kinase 1, epsilon |
| CYLD | cylindromatosis (turban tumor syndrome) |
| DALRD3 | DALR anticodon binding domain containing 3 |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| FAM155A | family with sequence similarity 155, member A |
| FAM186A | family with sequence similarity 186, member A |
| GAMT | guanidinoacetate N-methyltransferase |
| GRB7 | growth factor receptor-bound protein 7 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRK5 | G protein-coupled receptor kinase 5 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HDAC5 | histone deacetylase 5 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIRA | histone cell cycle regulator |
| HOMER3 | homer scaffolding protein 3 |
| HOXA10 | homeobox A10 |
| HSF1 | heat shock transcription factor 1 |
| HTR3A | 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| INHBE | inhibin, beta E |
| IRS2 | insulin receptor substrate 2 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KAT6A | K(lysine) acetyltransferase 6A |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KRT19P2 | keratin 19 pseudogene 2 |
| LBP | lipopolysaccharide binding protein |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| MAP4 | microtubule-associated protein 4 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MED16 | mediator complex subunit 16 |
| MEGF8 | multiple EGF-like-domains 8 |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MYL10 | myosin, light chain 10, regulatory |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NDRG2 | NDRG family member 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NUP214 | nucleoporin 214kDa |
| OAZ2 | ornithine decarboxylase antizyme 2 |
| OGFR | opioid growth factor receptor |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PLK3 | polo-like kinase 3 |
| PLLP | plasmolipin |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PQLC2 | PQ loop repeat containing 2 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PSG6 | pregnancy specific beta-1-glycoprotein 6 |
| PTGDR2 | prostaglandin D2 receptor 2 |
| RELN | reelin |
| RPS11 | ribosomal protein S11 |
| RRAGD | Ras-related GTP binding D |
| RRP1B | ribosomal RNA processing 1B |
| SH2D3A | SH2 domain containing 3A |
| SKIL | SKI-like proto-oncogene |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SYNJ2 | synaptojanin 2 |
| TBX19 | T-box 19 |
| TGM2 | transglutaminase 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TPM3 | tropomyosin 3 |
| TRIM3 | tripartite motif containing 3 |
| TTC22 | tetratricopeptide repeat domain 22 |
| TUBA3C | tubulin, alpha 3c |
| UPK3B | uroplakin 3B |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF747 | zinc finger protein 747 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| AFF4 | AF4/FMR2 family, member 4 |
| ALPK1 | alpha-kinase 1 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| AXIN1 | axin 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCDC176 | coiled-coil domain containing 176 |
| CCNO | cyclin O |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLDND1 | claudin domain containing 1 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| COG4 | component of oligomeric golgi complex 4 |
| COG7 | component of oligomeric golgi complex 7 |
| CORT | cortistatin |
| CST6 | cystatin E/M |
| CYP27B1 | cytochrome P450, family 27, subfamily B, polypeptide 1 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DOCK1 | dedicator of cytokinesis 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FAM172A | family with sequence similarity 172, member A |
| FAM188A | family with sequence similarity 188, member A |
| FBRS | fibrosin |
| FLCN | folliculin |
| FOXJ2 | forkhead box J2 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR143 | G protein-coupled receptor 143 |
| GPX2 | glutathione peroxidase 2 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IFI35 | interferon-induced protein 35 |
| IFT22 | intraflagellar transport 22 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL22 | interleukin 22 |
| LHX6 | LIM homeobox 6 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAGI1 | membrane associated guanylate kinase, WW and PDZ domain containing 1 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYO1F | myosin IF |
| NCSTN | nicastrin |
| NHEJ1 | nonhomologous end-joining factor 1 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| ODF2 | outer dense fiber of sperm tails 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PCDHA6 | protocadherin alpha 6 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD2 | phospholipase D2 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PMP22 | peripheral myelin protein 22 |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| R3HDM2 | R3H domain containing 2 |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| REEP1 | receptor accessory protein 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPP14 | ribonuclease P/MRP 14kDa subunit |
| RRAGB | Ras-related GTP binding B |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAI | suppressor of cancer cell invasion |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SSFA2 | sperm specific antigen 2 |
| TCP10 | t-complex 10 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TTC31 | tetratricopeptide repeat domain 31 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| USP21 | ubiquitin specific peptidase 21 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VGF | VGF nerve growth factor inducible |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF350 | zinc finger protein 350 |
