| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the physostigmine-5749 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAGAB | alpha- and gamma-adaptin binding protein |
| ABHD8 | abhydrolase domain containing 8 |
| ACAN | aggrecan |
| ACO2 | aconitase 2, mitochondrial |
| ACPP | acid phosphatase, prostate |
| ADGRL2 | adhesion G protein-coupled receptor L2 |
| ADH7 | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| AOC3 | amine oxidase, copper containing 3 |
| ARMC4 | armadillo repeat containing 4 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B9D2 | B9 protein domain 2 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C22ORF24 | chromosome 22 open reading frame 24 |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CCR4 | chemokine (C-C motif) receptor 4 |
| CD163 | CD163 molecule |
| CD33 | CD33 molecule |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CREBZF | CREB/ATF bZIP transcription factor |
| CREM | cAMP responsive element modulator |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJC16 | DnaJ (Hsp40) homolog, subfamily C, member 16 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| ELMO3 | engulfment and cell motility 3 |
| ENO3 | enolase 3 (beta, muscle) |
| EPS8L1 | EPS8-like 1 |
| FCMR | Fc fragment of IgM receptor |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FGL2 | fibrinogen-like 2 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FRMD1 | FERM domain containing 1 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GGT1 | gamma-glutamyltransferase 1 |
| GYG2 | glycogenin 2 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXD1 | homeobox D1 |
| HRG | histidine-rich glycoprotein |
| HTR1F | 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled |
| IL2RG | interleukin 2 receptor, gamma |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| IQCK | IQ motif containing K |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KIAA1109 | KIAA1109 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KYNU | kynureninase |
| LDB3 | LIM domain binding 3 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| MEF2C | myocyte enhancer factor 2C |
| MTMR8 | myotubularin related protein 8 |
| NDRG2 | NDRG family member 2 |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| PADI2 | peptidyl arginine deiminase, type II |
| PAX5 | paired box 5 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PNLIPRP2 | pancreatic lipase-related protein 2 |
| POU4F1 | POU class 4 homeobox 1 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PTCRA | pre T-cell antigen receptor alpha |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| RFPL3 | ret finger protein-like 3 |
| RHEB | Ras homolog enriched in brain |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SFRP4 | secreted frizzled-related protein 4 |
| SH3BP2 | SH3-domain binding protein 2 |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SPHK2 | sphingosine kinase 2 |
| STS | steroid sulfatase (microsomal), isozyme S |
| TGFA | transforming growth factor, alpha |
| TJP3 | tight junction protein 3 |
| TMEM246 | transmembrane protein 246 |
| TOM1L2 | target of myb1-like 2 (chicken) |
| TRIM29 | tripartite motif containing 29 |
| TTC12 | tetratricopeptide repeat domain 12 |
| UCP1 | uncoupling protein 1 (mitochondrial, proton carrier) |
| WDR33 | WD repeat domain 33 |
| WDR55 | WD repeat domain 55 |
| XDH | xanthine dehydrogenase |
| YIPF2 | Yip1 domain family, member 2 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ACVR2B | activin A receptor, type IIB |
| ALPK1 | alpha-kinase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| C17ORF53 | chromosome 17 open reading frame 53 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CA8 | carbonic anhydrase VIII |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CDK6 | cyclin-dependent kinase 6 |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CEP170B | centrosomal protein 170B |
| CES3 | carboxylesterase 3 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CNTLN | centlein, centrosomal protein |
| CRLF1 | cytokine receptor-like factor 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DBF4B | DBF4 zinc finger B |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EDAR | ectodysplasin A receptor |
| FAT4 | FAT atypical cadherin 4 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GPR3 | G protein-coupled receptor 3 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H2AI | histone cluster 1, H2ai |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 |
| HOXA4 | homeobox A4 |
| HOXB9 | homeobox B9 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IFNA14 | interferon, alpha 14 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| JAM3 | junctional adhesion molecule 3 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA1107 | KIAA1107 |
| LOC729164 | hCG1732469 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MAGEB2 | melanoma antigen family B2 |
| MAP6D1 | MAP6 domain containing 1 |
| MILR1 | mast cell immunoglobulin-like receptor 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| MYH15 | myosin, heavy chain 15 |
| MYL5 | myosin, light chain 5, regulatory |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NPY1R | neuropeptide Y receptor Y1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OTUD3 | OTU deubiquitinase 3 |
| POM121 | POM121 transmembrane nucleoporin |
| POU3F2 | POU class 3 homeobox 2 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRR4 | proline rich 4 (lacrimal) |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit |
| SH2D2A | SH2 domain containing 2A |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNHG3 | small nucleolar RNA host gene 3 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TENM1 | teneurin transmembrane protein 1 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM104 | transmembrane protein 104 |
| TRIM66 | tripartite motif containing 66 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| USP19 | ubiquitin specific peptidase 19 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VN1R1 | vomeronasal 1 receptor 1 |
| WDR78 | WD repeat domain 78 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF230 | zinc finger protein 230 |
| ZNF362 | zinc finger protein 362 |
| ZNF415 | zinc finger protein 415 |
| ZNF862 | zinc finger protein 862 |
| ZXDC | ZXD family zinc finger C |
