| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the physostigmine-6226 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABLIM3 | actin binding LIM protein family, member 3 |
| AKAP10 | A kinase (PRKA) anchor protein 10 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| BTBD7 | BTB (POZ) domain containing 7 |
| BTK | Bruton agammaglobulinemia tyrosine kinase |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit |
| CD52 | CD52 molecule |
| CDHR2 | cadherin-related family member 2 |
| CDK13 | cyclin-dependent kinase 13 |
| CDK5R1 | cyclin-dependent kinase 5, regulatory subunit 1 (p35) |
| CFAP69 | cilia and flagella associated protein 69 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHKB | choline kinase beta |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CORT | cortistatin |
| CTNS | cystinosin, lysosomal cystine transporter |
| CUL4B | cullin 4B |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DSCAM | Down syndrome cell adhesion molecule |
| DSCR3 | Down syndrome critical region 3 |
| DUSP3 | dual specificity phosphatase 3 |
| DYRK2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| FCMR | Fc fragment of IgM receptor |
| FGF23 | fibroblast growth factor 23 |
| FLJ11292 | |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GP2 | glycoprotein 2 (zymogen granule membrane) |
| GPATCH2L | G patch domain containing 2-like |
| GPR27 | G protein-coupled receptor 27 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HAND1 | heart and neural crest derivatives expressed 1 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HRASLS2 | HRAS-like suppressor 2 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IGSF1 | immunoglobulin superfamily, member 1 |
| IL11 | interleukin 11 |
| INHBA | inhibin, beta A |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KDM5A | lysine (K)-specific demethylase 5A |
| KIAA1456 | KIAA1456 |
| LHX6 | LIM homeobox 6 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LRRC14 | leucine rich repeat containing 14 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MDM4 | MDM4, p53 regulator |
| MFAP3L | microfibrillar-associated protein 3-like |
| MIIP | migration and invasion inhibitory protein |
| MYCL | v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
| NAG18 | NAG18 mRNA |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| OCA2 | oculocutaneous albinism II |
| OTUD3 | OTU deubiquitinase 3 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PHC3 | polyhomeotic homolog 3 (Drosophila) |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPL10 | ribosomal protein L10 |
| RUNX1 | runt-related transcription factor 1 |
| SERHL2 | serine hydrolase-like 2 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STX7 | syntaxin 7 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| SYNC | syncoilin, intermediate filament protein |
| SYNGR1 | synaptogyrin 1 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| TLE2 | transducin-like enhancer of split 2 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| UBE3A | ubiquitin protein ligase E3A |
| VASH2 | vasohibin 2 |
| ZBTB14 | zinc finger and BTB domain containing 14 |
| ZCCHC11 | zinc finger, CCHC domain containing 11 |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF287 | zinc finger protein 287 |
| ZNF318 | zinc finger protein 318 |
| ZNF440 | zinc finger protein 440 |
| ZNF442 | zinc finger protein 442 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ACVR2B | activin A receptor, type IIB |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ARID4A | AT rich interactive domain 4A (RBP1-like) |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BEX4 | brain expressed, X-linked 4 |
| BTBD3 | BTB (POZ) domain containing 3 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCNJ | cyclin J |
| CDK3 | cyclin-dependent kinase 3 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| COL4A5 | collagen, type IV, alpha 5 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DUSP8 | dual specificity phosphatase 8 |
| EML4 | echinoderm microtubule associated protein like 4 |
| EPN3 | epsin 3 |
| EPPK1 | epiplakin 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERCC5 | excision repair cross-complementation group 5 |
| FBXO22 | F-box protein 22 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FOXD1 | forkhead box D1 |
| FOXK2 | forkhead box K2 |
| FPGS | folylpolyglutamate synthase |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GCA | grancalcin, EF-hand calcium binding protein |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H3G | histone cluster 1, H3g |
| ICE2 | interactor of little elongation complex ELL subunit 2 |
| IL17RA | interleukin 17 receptor A |
| IMPACT | impact RWD domain protein |
| IRF9 | interferon regulatory factor 9 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0232 | KIAA0232 |
| LAMB2 | laminin, beta 2 (laminin S) |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LOC730101 | uncharacterized LOC730101 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MORC3 | MORC family CW-type zinc finger 3 |
| MPI | mannose phosphate isomerase |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PLD3 | phospholipase D family, member 3 |
| PMP22 | peripheral myelin protein 22 |
| PPOX | protoporphyrinogen oxidase |
| PROCR | protein C receptor, endothelial |
| PRSS22 | protease, serine, 22 |
| PTBP2 | polypyrimidine tract binding protein 2 |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBL1 | retinoblastoma-like 1 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STXBP2 | syntaxin binding protein 2 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SYNGR3 | synaptogyrin 3 |
| TCTN1 | tectonic family member 1 |
| TEAD3 | TEA domain family member 3 |
| THOP1 | thimet oligopeptidase 1 |
| TKFC | triokinase/FMN cyclase |
| TMEM115 | transmembrane protein 115 |
| TMEM159 | transmembrane protein 159 |
| TNIP1 | TNFAIP3 interacting protein 1 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| USP18 | ubiquitin specific peptidase 18 |
| WWC2 | WW and C2 domain containing 2 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF271P | zinc finger protein 271, pseudogene |
| ZNF408 | zinc finger protein 408 |
| ZNF492 | zinc finger protein 492 |
| ZNF573 | zinc finger protein 573 |
| ZNF675 | zinc finger protein 675 |
| ZNF692 | zinc finger protein 692 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF787 | zinc finger protein 787 |
