pi3k Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+). (Gene Ontology, GO_0016303)
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Genes

217 proteins co-occuring with the biological term pi3k in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
ACACA acetyl-CoA carboxylase alpha
ACVR1B activin A receptor, type IB
ADK adenosine kinase
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT1S1 AKT1 substrate 1 (proline-rich)
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALYREF Aly/REF export factor
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARHGAP22 Rho GTPase activating protein 22
ATM ATM serine/threonine kinase
ATXN1 ataxin 1
AURKA aurora kinase A
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BCR breakpoint cluster region
BIRC5 baculoviral IAP repeat containing 5
BMX BMX non-receptor tyrosine kinase
BRCA1 breast cancer 1, early onset
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC88A coiled-coil domain containing 88A
CCND1 cyclin D1
CCND2 cyclin D2
CD19 CD19 molecule
CD22 CD22 molecule
CD300LF CD300 molecule-like family member f
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFL1 cofilin 1 (non-muscle)
CHEK1 checkpoint kinase 1
CHUK conserved helix-loop-helix ubiquitous kinase
CREB1 cAMP responsive element binding protein 1
CSF1R colony stimulating factor 1 receptor
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
EGFR epidermal growth factor receptor
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4B eukaryotic translation initiation factor 4B
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
EP300 E1A binding protein p300
EPHA2 EPH receptor A2
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERRFI1 ERBB receptor feedback inhibitor 1
ESR1 estrogen receptor 1
ESYT1 extended synaptotagmin-like protein 1
EXOC4 exocyst complex component 4
EZR ezrin
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGB fibrinogen beta chain
FHIT fragile histidine triad
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXO4 forkhead box O4
FOXO6 forkhead box O6
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GRB10 growth factor receptor-bound protein 10
GRIA1 glutamate receptor, ionotropic, AMPA 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
H2AFX H2A histone family, member X
HIST1H3A histone cluster 1, H3a
HSF1 heat shock transcription factor 1
IGF1R insulin-like growth factor 1 receptor
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL21R interleukin 21 receptor
IL2RB interleukin 2 receptor, beta
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IRS1 insulin receptor substrate 1
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB4 integrin, beta 4
JUN jun proto-oncogene
KAT5 K(lysine) acetyltransferase 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAT linker for activation of T cells
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LIME1 Lck interacting transmembrane adaptor 1
LIMK1 LIM domain kinase 1
LRP6 low density lipoprotein receptor-related protein 6
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MET MET proto-oncogene, receptor tyrosine kinase
MPL MPL proto-oncogene, thrombopoietin receptor
MSN moesin
MST1R macrophage stimulating 1 receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYL12B myosin, light chain 12B, regulatory
NAGK N-acetylglucosamine kinase
NDRG1 N-myc downstream regulated 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NYAP2 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2
OCLN occludin
P2RX6 purinergic receptor P2X, ligand gated ion channel, 6
PA2G4 proliferation-associated 2G4, 38kDa
PALLD palladin, cytoskeletal associated protein
PDCD6IP programmed cell death 6 interacting protein
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PELP1 proline, glutamate and leucine rich protein 1
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PHB prohibitin
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIKFYVE phosphoinositide kinase, FYVE finger containing
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLD2 phospholipase D2
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCD protein kinase C, delta
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PXN paxillin
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RANBP3 RAN binding protein 3
RARG retinoic acid receptor, gamma
RB1 retinoblastoma 1
RDX radixin
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RICTOR RPTOR independent companion of MTOR, complex 2
RPLP2 ribosomal protein, large, P2
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RPTOR regulatory associated protein of MTOR, complex 1
RUNX2 runt-related transcription factor 2
SET SET nuclear proto-oncogene
SGK1 serum/glucocorticoid regulated kinase 1
SGK3 serum/glucocorticoid regulated kinase family, member 3
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD5 SMAD family member 5
SP1 Sp1 transcription factor
SPI1 Spi-1 proto-oncogene
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSH1 slingshot protein phosphatase 1
SSTR2 somatostatin receptor 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
TBC1D4 TBC1 domain family, member 4
TGFBR1 transforming growth factor, beta receptor 1
TIGIT T cell immunoreceptor with Ig and ITIM domains
TLR5 toll-like receptor 5
TLR8 toll-like receptor 8
TNK2 tyrosine kinase, non-receptor, 2
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TPM1 tropomyosin 1 (alpha)
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
VAV1 vav 1 guanine nucleotide exchange factor
VIM vimentin
WNK1 WNK lysine deficient protein kinase 1
WNK2 WNK lysine deficient protein kinase 2
ZFYVE16 zinc finger, FYVE domain containing 16