picotamide-1387 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the picotamide-1387 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APAF1 apoptotic peptidase activating factor 1
ARFRP1 ADP-ribosylation factor related protein 1
ARHGAP33 Rho GTPase activating protein 33
ARRB2 arrestin, beta 2
ASNSD1 asparagine synthetase domain containing 1
ATP10A ATPase, class V, type 10A
C1ORF95 chromosome 1 open reading frame 95
C5ORF30 chromosome 5 open reading frame 30
C8ORF44 chromosome 8 open reading frame 44
CA14 carbonic anhydrase XIV
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CD37 CD37 molecule
CFDP1 craniofacial development protein 1
CLIP1 CAP-GLY domain containing linker protein 1
CLTCL1 clathrin, heavy chain-like 1
CNOT3 CCR4-NOT transcription complex, subunit 3
COL5A3 collagen, type V, alpha 3
DBT dihydrolipoamide branched chain transacylase E2
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
ECE1 endothelin converting enzyme 1
FBXO42 F-box protein 42
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
GBAP1 glucosidase, beta, acid pseudogene 1
GSTM4 glutathione S-transferase mu 4
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
GUSBP3 glucuronidase, beta pseudogene 3
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HCFC2 host cell factor C2
HOXC4 homeobox C4
HRH3 histamine receptor H3
HTRA2 HtrA serine peptidase 2
IGF1R insulin-like growth factor 1 receptor
IGFBP7 insulin-like growth factor binding protein 7
IRGQ immunity-related GTPase family, Q
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIF23 kinesin family member 23
KIF3C kinesin family member 3C
LIMD2 LIM domain containing 2
LIN7A lin-7 homolog A (C. elegans)
LRP12 low density lipoprotein receptor-related protein 12
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGED2 melanoma antigen family D2
MSH3 mutS homolog 3
MZF1 myeloid zinc finger 1
NARFL nuclear prelamin A recognition factor-like
NCAPH2 non-SMC condensin II complex, subunit H2
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEK1 NIMA-related kinase 1
NENF neudesin neurotrophic factor
NPFFR1 neuropeptide FF receptor 1
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NR4A1 nuclear receptor subfamily 4, group A, member 1
NUCB1 nucleobindin 1
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NXF3 nuclear RNA export factor 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PDCD11 programmed cell death 11
PITPNA phosphatidylinositol transfer protein, alpha
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKP4 plakophilin 4
POLG polymerase (DNA directed), gamma
POM121L2 POM121 transmembrane nucleoporin-like 2
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP6R2 protein phosphatase 6, regulatory subunit 2
PROL1 proline rich, lacrimal 1
PRR4 proline rich 4 (lacrimal)
PTBP3 polypyrimidine tract binding protein 3
PVR poliovirus receptor
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RNF141 ring finger protein 141
SIRT2 sirtuin 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein
STAR steroidogenic acute regulatory protein
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TAS2R1 taste receptor, type 2, member 1
TBC1D22A TBC1 domain family, member 22A
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
THUMPD2 THUMP domain containing 2
TM9SF4 transmembrane 9 superfamily protein member 4
TMEM127 transmembrane protein 127
TRAC T cell receptor alpha constant
TTLL4 tubulin tyrosine ligase-like family member 4
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UGDH UDP-glucose 6-dehydrogenase
USF2 upstream transcription factor 2, c-fos interacting
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae)
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
WDR46 WD repeat domain 46
ZKSCAN4 zinc finger with KRAB and SCAN domains 4
ZNF580 zinc finger protein 580
ZNF839 zinc finger protein 839

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM15 ADAM metallopeptidase domain 15
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ANXA2P2 annexin A2 pseudogene 2
APIP APAF1 interacting protein
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa
ATAD2B ATPase family, AAA domain containing 2B
ATG4A autophagy related 4A, cysteine peptidase
BDH2 3-hydroxybutyrate dehydrogenase, type 2
C12ORF49 chromosome 12 open reading frame 49
CALCOCO1 calcium binding and coiled-coil domain 1
CASZ1 castor zinc finger 1
CCDC130 coiled-coil domain containing 130
CCNA1 cyclin A1
CD151 CD151 molecule (Raph blood group)
CDC73 cell division cycle 73
CDCA3 cell division cycle associated 3
CEND1 cell cycle exit and neuronal differentiation 1
CEP170B centrosomal protein 170B
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLDN15 claudin 15
COPS5 COP9 signalosome subunit 5
CTSH cathepsin H
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DBF4 DBF4 zinc finger
DCAF10 DDB1 and CUL4 associated factor 10
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
ECD ecdysoneless homolog (Drosophila)
ENOPH1 enolase-phosphatase 1
ERCC8 excision repair cross-complementation group 8
EVL Enah/Vasp-like
FAM179B family with sequence similarity 179, member B
FBXL4 F-box and leucine-rich repeat protein 4
FGR FGR proto-oncogene, Src family tyrosine kinase
GALE UDP-galactose-4-epimerase
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
IER3IP1 immediate early response 3 interacting protein 1
IL2RB interleukin 2 receptor, beta
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
LBR lamin B receptor
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LYRM1 LYR motif containing 1
MAGEF1 melanoma antigen family F1
MED23 mediator complex subunit 23
MFSD11 major facilitator superfamily domain containing 11
MICU2 mitochondrial calcium uptake 2
MLYCD malonyl-CoA decarboxylase
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NAP1L4 nucleosome assembly protein 1-like 4
NOL6 nucleolar protein 6 (RNA-associated)
NOTCH1 notch 1
NT5C2 5'-nucleotidase, cytosolic II
NUBP2 nucleotide binding protein 2
OGFRL1 opioid growth factor receptor-like 1
ORC1 origin recognition complex, subunit 1
PARG poly (ADP-ribose) glycohydrolase
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PIBF1 progesterone immunomodulatory binding factor 1
PNOC prepronociceptin
PNRC1 proline-rich nuclear receptor coactivator 1
PXMP4 peroxisomal membrane protein 4, 24kDa
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RBBP5 retinoblastoma binding protein 5
RBMS3 RNA binding motif, single stranded interacting protein 3
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RHOC ras homolog family member C
RNF122 ring finger protein 122
RPAP1 RNA polymerase II associated protein 1
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCN1B sodium channel, voltage gated, type I beta subunit
SERTAD3 SERTA domain containing 3
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC25A38 solute carrier family 25, member 38
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SMNDC1 survival motor neuron domain containing 1
TEFM transcription elongation factor, mitochondrial
TEX40 testis expressed 40
TIPIN TIMELESS interacting protein
TMEM165 transmembrane protein 165
TMEM184B transmembrane protein 184B
TRIM8 tripartite motif containing 8
TST thiosulfate sulfurtransferase (rhodanese)
TTPAL tocopherol (alpha) transfer protein-like
TWF2 twinfilin actin binding protein 2
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2
YIPF5 Yip1 domain family, member 5
ZNF432 zinc finger protein 432
ZNF652 zinc finger protein 652
ZZZ3 zinc finger, ZZ-type containing 3