picotamide-2070 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the picotamide-2070 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABHD17B abhydrolase domain containing 17B
ABHD2 abhydrolase domain containing 2
ALPI alkaline phosphatase, intestinal
ASAP1-IT1 ASAP1 intronic transcript 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BATF3 basic leucine zipper transcription factor, ATF-like 3
BTN3A1 butyrophilin, subfamily 3, member A1
C19ORF73 chromosome 19 open reading frame 73
CABIN1 calcineurin binding protein 1
CASKIN2 CASK interacting protein 2
CCL20 chemokine (C-C motif) ligand 20
CCNJL cyclin J-like
CCNO cyclin O
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CES3 carboxylesterase 3
CORO2A coronin, actin binding protein, 2A
CORO7 coronin 7
DCAF4 DDB1 and CUL4 associated factor 4
DHODH dihydroorotate dehydrogenase (quinone)
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DSC2 desmocollin 2
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EFNA3 ephrin-A3
EGFL7 EGF-like-domain, multiple 7
EPS8L1 EPS8-like 1
ETV5 ets variant 5
EVA1B eva-1 homolog B (C. elegans)
FAM50B family with sequence similarity 50, member B
FBLN1 fibulin 1
FCMR Fc fragment of IgM receptor
FLJ11292
GOLGA2 golgin A2
GPR17 G protein-coupled receptor 17
GTPBP1 GTP binding protein 1
HEG1 heart development protein with EGF-like domains 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
IL2RG interleukin 2 receptor, gamma
KIAA1644 KIAA1644
LIG3 ligase III, DNA, ATP-dependent
LOC647070 uncharacterized LOC647070
LRRC40 leucine rich repeat containing 40
LRRK1 leucine-rich repeat kinase 1
MAPK11 mitogen-activated protein kinase 11
MOBP myelin-associated oligodendrocyte basic protein
MUC1 mucin 1, cell surface associated
MYOZ2 myozenin 2
MYRF myelin regulatory factor
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NPEPL1 aminopeptidase-like 1
NPR2 natriuretic peptide receptor 2
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PCDH9 protocadherin 9
PF4 platelet factor 4
PIDD1 p53-induced death domain protein 1
PLXNB3 plexin B3
PPARD peroxisome proliferator-activated receptor delta
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PTGES2 prostaglandin E synthase 2
RAB28 RAB28, member RAS oncogene family
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RARG retinoic acid receptor, gamma
RIBC2 RIB43A domain with coiled-coils 2
RTEL1 regulator of telomere elongation helicase 1
SCAMP5 secretory carrier membrane protein 5
SCARB2 scavenger receptor class B, member 2
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SETD6 SET domain containing 6
SH3BP2 SH3-domain binding protein 2
SLC17A2 solute carrier family 17, member 2
SLC41A3 solute carrier family 41, member 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SPATA5L1 spermatogenesis associated 5-like 1
SRSF7 serine/arginine-rich splicing factor 7
STON1 stonin 1
SUGP1 SURP and G patch domain containing 1
TEP1 telomerase-associated protein 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TLN2 talin 2
TMEM53 transmembrane protein 53
TRIM33 tripartite motif containing 33
TSPAN9 tetraspanin 9
TTC38 tetratricopeptide repeat domain 38
TXLNG taxilin gamma
UBOX5 U-box domain containing 5
UNC45A unc-45 homolog A (C. elegans)
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VGLL3 vestigial-like family member 3
WNT10B wingless-type MMTV integration site family, member 10B
YIPF2 Yip1 domain family, member 2
ZNF34 zinc finger protein 34
ZNF609 zinc finger protein 609
ZNF710 zinc finger protein 710
ZNRD1-AS1 ZNRD1 antisense RNA 1

decreased expression

Symbol Name
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ANKRD36B ankyrin repeat domain 36B
ASB13 ankyrin repeat and SOCS box containing 13
AURKB aurora kinase B
BAHD1 bromo adjacent homology domain containing 1
BCAS3 breast carcinoma amplified sequence 3
BCL2L2 BCL2-like 2
BDNF brain-derived neurotrophic factor
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C16ORF59 chromosome 16 open reading frame 59
C8ORF60 chromosome 8 open reading frame 60
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC91 coiled-coil domain containing 91
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COBL cordon-bleu WH2 repeat protein
CRYBA2 crystallin, beta A2
CTSD cathepsin D
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DET1 de-etiolated homolog 1 (Arabidopsis)
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
EXOC2 exocyst complex component 2
EXOSC5 exosome component 5
F2R coagulation factor II (thrombin) receptor
FA2H fatty acid 2-hydroxylase
FAM155A family with sequence similarity 155, member A
FBXW12 F-box and WD repeat domain containing 12
FGD1 FYVE, RhoGEF and PH domain containing 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GLT8D2 glycosyltransferase 8 domain containing 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HDAC7 histone deacetylase 7
HIRA histone cell cycle regulator
HOMER2 homer scaffolding protein 2
HS1BP3 HCLS1 binding protein 3
HSPA4L heat shock 70kDa protein 4-like
HYAL3 hyaluronoglucosaminidase 3
ISL1 ISL LIM homeobox 1
KDM5C lysine (K)-specific demethylase 5C
KIFC1 kinesin family member C1
KIZ kizuna centrosomal protein
KLC2 kinesin light chain 2
KLHL12 kelch-like family member 12
KRT86 keratin 86, type II
LMNB1 lamin B1
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MAVS mitochondrial antiviral signaling protein
METTL2B methyltransferase like 2B
MIS18BP1 MIS18 binding protein 1
MON1B MON1 secretory trafficking family member B
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
OLFML2A olfactomedin-like 2A
OXR1 oxidation resistance 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PARP3 poly (ADP-ribose) polymerase family, member 3
PDZK1 PDZ domain containing 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
RAB4B RAB4B, member RAS oncogene family
RBL1 retinoblastoma-like 1
RCAN3 RCAN family member 3
RNF170 ring finger protein 170
RSRC1 arginine/serine-rich coiled-coil 1
RUSC2 RUN and SH3 domain containing 2
SCEL sciellin
SECISBP2 SECIS binding protein 2
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SNHG20 small nucleolar RNA host gene 20
SNPH syntaphilin
STK16 serine/threonine kinase 16
SYNJ2BP synaptojanin 2 binding protein
TASP1 taspase, threonine aspartase, 1
TMC5 transmembrane channel-like 5
TMEM242 transmembrane protein 242
TMEM260 transmembrane protein 260
TMEM8A transmembrane protein 8A
TRIM5 tripartite motif containing 5
TTBK2 tau tubulin kinase 2
TWSG1 twisted gastrulation BMP signaling modulator 1
USP18 ubiquitin specific peptidase 18
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZDHHC18 zinc finger, DHHC-type containing 18
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF180 zinc finger protein 180
ZNF23 zinc finger protein 23
ZNF408 zinc finger protein 408
ZNF426 zinc finger protein 426
ZNF562 zinc finger protein 562