picotamide-2233 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the picotamide-2233 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRG1 adhesion G protein-coupled receptor G1
ANKH ANKH inorganic pyrophosphate transport regulator
ATN1 atrophin 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C14ORF105 chromosome 14 open reading frame 105
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCR2 chemokine (C-C motif) receptor 2
CD101 CD101 molecule
CD1E CD1e molecule
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFAP45 cilia and flagella associated protein 45
CLDN11 claudin 11
CLIP2 CAP-GLY domain containing linker protein 2
CNIH3 cornichon family AMPA receptor auxiliary protein 3
COL1A1 collagen, type I, alpha 1
CPQ carboxypeptidase Q
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CXCR4 chemokine (C-X-C motif) receptor 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EFR3B EFR3 homolog B (S. cerevisiae)
EXOC6B exocyst complex component 6B
FAM76A family with sequence similarity 76, member A
FBLN1 fibulin 1
FCMR Fc fragment of IgM receptor
FGF4 fibroblast growth factor 4
FMO5 flavin containing monooxygenase 5
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GDF5 growth differentiation factor 5
GPR137 G protein-coupled receptor 137
GRK5 G protein-coupled receptor kinase 5
GSTP1 glutathione S-transferase pi 1
GZMK granzyme K (granzyme 3; tryptase II)
HDAC7 histone deacetylase 7
HIST1H2BL histone cluster 1, H2bl
HIST1H3I histone cluster 1, H3i
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA2 homeobox A2
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IGFBP7 insulin-like growth factor binding protein 7
IL2RG interleukin 2 receptor, gamma
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIAA1462 KIAA1462
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAPK11 mitogen-activated protein kinase 11
MEF2C myocyte enhancer factor 2C
MIER2 mesoderm induction early response 1, family member 2
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MX2 MX dynamin-like GTPase 2
MYCNOS MYCN opposite strand
NF1 neurofibromin 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NIPAL3 NIPA-like domain containing 3
NPAS2 neuronal PAS domain protein 2
NR1H4 nuclear receptor subfamily 1, group H, member 4
NTM neurotrimin
NXF2 nuclear RNA export factor 2
OAZ3 ornithine decarboxylase antizyme 3
OTUD7B OTU deubiquitinase 7B
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNB3 plexin B3
POLM polymerase (DNA directed), mu
PRB1 proline-rich protein BstNI subfamily 1
PSG4 pregnancy specific beta-1-glycoprotein 4
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RERE arginine-glutamic acid dipeptide (RE) repeats
RHBG Rh family, B glycoprotein (gene/pseudogene)
RHEB Ras homolog enriched in brain
RNASE4 ribonuclease, RNase A family, 4
RND1 Rho family GTPase 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RUNX1 runt-related transcription factor 1
SARM1 sterile alpha and TIR motif containing 1
SERHL2 serine hydrolase-like 2
SH3BP2 SH3-domain binding protein 2
SIRT4 sirtuin 4
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SUGP1 SURP and G patch domain containing 1
TBC1D2 TBC1 domain family, member 2
TBKBP1 TBK1 binding protein 1
TCF12 transcription factor 12
TPSG1 tryptase gamma 1
TSPAN9 tetraspanin 9
UPK2 uroplakin 2
USP9Y ubiquitin specific peptidase 9, Y-linked
YPEL1 yippee-like 1 (Drosophila)
ZCCHC14 zinc finger, CCHC domain containing 14
ZFP36L1 ZFP36 ring finger protein-like 1
ZNF76 zinc finger protein 76
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACAD10 acyl-CoA dehydrogenase family, member 10
ADTRP androgen-dependent TFPI-regulating protein
ALG12 ALG12, alpha-1,6-mannosyltransferase
AMT aminomethyltransferase
ANKRD7 ankyrin repeat domain 7
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARHGAP4 Rho GTPase activating protein 4
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ARMC4 armadillo repeat containing 4
ATP10D ATPase, class V, type 10D
BGLAP bone gamma-carboxyglutamate (gla) protein
C11ORF63 chromosome 11 open reading frame 63
C1ORF105 chromosome 1 open reading frame 105
C3 complement component 3
CCDC121 coiled-coil domain containing 121
CD34 CD34 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CDK18 cyclin-dependent kinase 18
CDK3 cyclin-dependent kinase 3
CDON cell adhesion associated, oncogene regulated
CLCF1 cardiotrophin-like cytokine factor 1
CNR2 cannabinoid receptor 2 (macrophage)
CRIP1 cysteine-rich protein 1 (intestinal)
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ERCC6 excision repair cross-complementation group 6
FADS2 fatty acid desaturase 2
FAM155A family with sequence similarity 155, member A
FAM189A2 family with sequence similarity 189, member A2
FBXL7 F-box and leucine-rich repeat protein 7
GLRA1 glycine receptor, alpha 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR143 G protein-coupled receptor 143
GPR157 G protein-coupled receptor 157
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HDAC11 histone deacetylase 11
HIST1H2BJ histone cluster 1, H2bj
HIST1H4A histone cluster 1, H4a
HOXA4 homeobox A4
HOXC8 homeobox C8
HPX hemopexin
IDI2-AS1 IDI2 antisense RNA 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGFBP6 insulin-like growth factor binding protein 6
IL12RB1 interleukin 12 receptor, beta 1
IQCG IQ motif containing G
JMJD4 jumonji domain containing 4
KLHL28 kelch-like family member 28
LAMP3 lysosomal-associated membrane protein 3
MAGEB2 melanoma antigen family B2
MYOZ1 myozenin 1
NACA2 nascent polypeptide-associated complex alpha subunit 2
NEUROD4 neuronal differentiation 4
NT5DC3 5'-nucleotidase domain containing 3
OLFML3 olfactomedin-like 3
OVGP1 oviductal glycoprotein 1, 120kDa
OVOL1 ovo-like zinc finger 1
PCDHA6 protocadherin alpha 6
PGPEP1 pyroglutamyl-peptidase I
PHEX phosphate regulating endopeptidase homolog, X-linked
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLD3 phospholipase D family, member 3
POM121 POM121 transmembrane nucleoporin
PP14571 uncharacterized LOC100130449
PQLC2 PQ loop repeat containing 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRODH proline dehydrogenase (oxidase) 1
RAB40C RAB40C, member RAS oncogene family
RCAN3 RCAN family member 3
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHBDD3 rhomboid domain containing 3
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
S100A4 S100 calcium binding protein A4
SCML2 sex comb on midleg-like 2 (Drosophila)
SEC14L5 SEC14-like 5 (S. cerevisiae)
STAB2 stabilin 2
STX1A syntaxin 1A (brain)
SYNGR3 synaptogyrin 3
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TDRD1 tudor domain containing 1
TLR2 toll-like receptor 2
TMCC2 transmembrane and coiled-coil domain family 2
TUBA3C tubulin, alpha 3c
UBTD1 ubiquitin domain containing 1
USP36 ubiquitin specific peptidase 36
VASH2 vasohibin 2
VLDLR very low density lipoprotein receptor
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WNT10B wingless-type MMTV integration site family, member 10B
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZBTB33 zinc finger and BTB domain containing 33
ZNF324 zinc finger protein 324
ZNF329 zinc finger protein 329
ZNF516 zinc finger protein 516