picotamide-6787 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the picotamide-6787 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ARID4B AT rich interactive domain 4B (RBP1-like)
ARMC4 armadillo repeat containing 4
ARTN artemin
ATF7IP activating transcription factor 7 interacting protein
ATG10 autophagy related 10
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BIRC7 baculoviral IAP repeat containing 7
BLZF1 basic leucine zipper nuclear factor 1
BMP10 bone morphogenetic protein 10
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1RL complement component 1, r subcomponent-like
C3 complement component 3
CADM3 cell adhesion molecule 3
CCDC40 coiled-coil domain containing 40
CD40 CD40 molecule, TNF receptor superfamily member 5
CD58 CD58 molecule
CLCF1 cardiotrophin-like cytokine factor 1
CNN1 calponin 1, basic, smooth muscle
COL10A1 collagen, type X, alpha 1
DGCR8 DGCR8 microprocessor complex subunit
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DUSP9 dual specificity phosphatase 9
EDAR ectodysplasin A receptor
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FGF6 fibroblast growth factor 6
FRMD1 FERM domain containing 1
GAB2 GRB2-associated binding protein 2
GBP1 guanylate binding protein 1, interferon-inducible
GDF3 growth differentiation factor 3
GLIPR1 GLI pathogenesis-related 1
GOLGA8A golgin A8 family, member A
GPR25 G protein-coupled receptor 25
GSPT1 G1 to S phase transition 1
HCRP1 hepatocellular carcinoma-related HCRP1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-E major histocompatibility complex, class I, E
HOXA4 homeobox A4
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HYAL3 hyaluronoglucosaminidase 3
IL1B interleukin 1, beta
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JAK3 Janus kinase 3
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIAA0040 KIAA0040
LRRC14 leucine rich repeat containing 14
MARK2 MAP/microtubule affinity-regulating kinase 2
MBNL3 muscleblind-like splicing regulator 3
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED6 mediator complex subunit 6
MYBPC3 myosin binding protein C, cardiac
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NDRG2 NDRG family member 2
NPAS2 neuronal PAS domain protein 2
NXPH4 neurexophilin 4
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PEX26 peroxisomal biogenesis factor 26
PGAM2 phosphoglycerate mutase 2 (muscle)
PITX2 paired-like homeodomain 2
PLD3 phospholipase D family, member 3
PLXNB3 plexin B3
PSG3 pregnancy specific beta-1-glycoprotein 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTHLH parathyroid hormone-like hormone
PVR poliovirus receptor
RAD51 RAD51 recombinase
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS4Y1 ribosomal protein S4, Y-linked 1
SHOX2 short stature homeobox 2
SIVA1 SIVA1, apoptosis-inducing factor
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SPAG8 sperm associated antigen 8
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPINK5 serine peptidase inhibitor, Kazal type 5
SPN sialophorin
SPPL2B signal peptide peptidase like 2B
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAT5B signal transducer and activator of transcription 5B
STOML1 stomatin (EPB72)-like 1
TBC1D22B TBC1 domain family, member 22B
TJAP1 tight junction associated protein 1 (peripheral)
TJP3 tight junction protein 3
TNXB tenascin XB
TPMT thiopurine S-methyltransferase
VASH2 vasohibin 2
VWA5A von Willebrand factor A domain containing 5A
YPEL1 yippee-like 1 (Drosophila)
ZFP64 ZFP64 zinc finger protein
ZNF41 zinc finger protein 41
ZNF862 zinc finger protein 862
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ADRA2C adrenoceptor alpha 2C
APOD apolipoprotein D
ARC activity-regulated cytoskeleton-associated protein
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAG4 BCL2-associated athanogene 4
BAGE B melanoma antigen
C11ORF80 chromosome 11 open reading frame 80
C19ORF73 chromosome 19 open reading frame 73
C22ORF46 chromosome 22 open reading frame 46
CALCOCO1 calcium binding and coiled-coil domain 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC134 coiled-coil domain containing 134
CCDC186 coiled-coil domain containing 186
CD79B CD79b molecule, immunoglobulin-associated beta
CD82 CD82 molecule
CDKL3 cyclin-dependent kinase-like 3
CTAGE9 CTAGE family, member 9
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTSF cathepsin F
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUSP8 dual specificity phosphatase 8
FAM50B family with sequence similarity 50, member B
FAM63A family with sequence similarity 63, member A
FBXL15 F-box and leucine-rich repeat protein 15
GAN gigaxonin
GLB1L2 galactosidase, beta 1-like 2
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRB7 growth factor receptor-bound protein 7
GRTP1 growth hormone regulated TBC protein 1
GUSBP3 glucuronidase, beta pseudogene 3
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HOXC8 homeobox C8
IFI6 interferon, alpha-inducible protein 6
IL4R interleukin 4 receptor
INO80D INO80 complex subunit D
IRF1 interferon regulatory factor 1
IRF9 interferon regulatory factor 9
KDM5C lysine (K)-specific demethylase 5C
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KLC2 kinesin light chain 2
LARP6 La ribonucleoprotein domain family, member 6
LHX6 LIM homeobox 6
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC61 leucine rich repeat containing 61
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAST3 microtubule associated serine/threonine kinase 3
METTL2B methyltransferase like 2B
MTERF4 mitochondrial transcription termination factor 4
MUM1 melanoma associated antigen (mutated) 1
MYO1E myosin IE
NABP2 nucleic acid binding protein 2
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NNAT neuronatin
NOL6 nucleolar protein 6 (RNA-associated)
NT5E 5'-nucleotidase, ecto (CD73)
PADI1 peptidyl arginine deiminase, type I
PCDH12 protocadherin 12
PGPEP1 pyroglutamyl-peptidase I
PHACTR4 phosphatase and actin regulator 4
PLD2 phospholipase D2
PLEKHA6 pleckstrin homology domain containing, family A member 6
POMT2 protein-O-mannosyltransferase 2
RANGRF RAN guanine nucleotide release factor
RGS19 regulator of G-protein signaling 19
RIBC2 RIB43A domain with coiled-coils 2
ROM1 retinal outer segment membrane protein 1
SALL2 spalt-like transcription factor 2
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A9 solute carrier family 12, member 9
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SYNGR3 synaptogyrin 3
TBX19 T-box 19
TCHH trichohyalin
TEP1 telomerase-associated protein 1
THBS3 thrombospondin 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM180 transmembrane protein 180
TMEM53 transmembrane protein 53
TRABD TraB domain containing
TRAIP TRAF interacting protein
TRAPPC11 trafficking protein particle complex 11
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TRPV1 transient receptor potential cation channel, subfamily V, member 1
USP20 ubiquitin specific peptidase 20
USP27X ubiquitin specific peptidase 27, X-linked
VEZT vezatin, adherens junctions transmembrane protein
WDR25 WD repeat domain 25
XK X-linked Kx blood group
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFHX3 zinc finger homeobox 3
ZNF205 zinc finger protein 205
ZNF286A zinc finger protein 286A
ZNF747 zinc finger protein 747