| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the picrotoxinin-2161 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH1L1 | aldehyde dehydrogenase 1 family, member L1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| ATP5D | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit |
| ATP9B | ATPase, class II, type 9B |
| ATXN7L1 | ataxin 7-like 1 |
| B9D2 | B9 protein domain 2 |
| BAIAP2 | BAI1-associated protein 2 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CASZ1 | castor zinc finger 1 |
| CD86 | CD86 molecule |
| CEP170B | centrosomal protein 170B |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CREM | cAMP responsive element modulator |
| CTSF | cathepsin F |
| CXCR3 | chemokine (C-X-C motif) receptor 3 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DBT | dihydrolipoamide branched chain transacylase E2 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| EFNA4 | ephrin-A4 |
| EPS8L1 | EPS8-like 1 |
| FAM155A | family with sequence similarity 155, member A |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| GFER | growth factor, augmenter of liver regeneration |
| GLE1 | GLE1 RNA export mediator |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GYG2 | glycogenin 2 |
| HAMP | hepcidin antimicrobial peptide |
| HFE | hemochromatosis |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BI | histone cluster 1, H2bi |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFI6 | interferon, alpha-inducible protein 6 |
| IRF6 | interferon regulatory factor 6 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| ITGB5 | integrin, beta 5 |
| JUN | jun proto-oncogene |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KLK2 | kallikrein-related peptidase 2 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LY6G6D | lymphocyte antigen 6 complex, locus G6D |
| MAP4 | microtubule-associated protein 4 |
| MAU2 | MAU2 sister chromatid cohesion factor |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MMP19 | matrix metallopeptidase 19 |
| MSRB2 | methionine sulfoxide reductase B2 |
| MST1L | macrophage stimulating 1-like |
| NBR2 | neighbor of BRCA1 gene 2 (non-protein coding) |
| NDNF | neuron-derived neurotrophic factor |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| PADI2 | peptidyl arginine deiminase, type II |
| PADI4 | peptidyl arginine deiminase, type IV |
| PCLO | piccolo presynaptic cytomatrix protein |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PYGB | phosphorylase, glycogen; brain |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RGS14 | regulator of G-protein signaling 14 |
| RHOT2 | ras homolog family member T2 |
| RPS11 | ribosomal protein S11 |
| RUNDC3B | RUN domain containing 3B |
| RUNX3 | runt-related transcription factor 3 |
| S100A12 | S100 calcium binding protein A12 |
| S100A8 | S100 calcium binding protein A8 |
| SAMD14 | sterile alpha motif domain containing 14 |
| SF3A2 | splicing factor 3a, subunit 2, 66kDa |
| SIN3B | SIN3 transcription regulator family member B |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
| SMTN | smoothelin |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| SYNDIG1 | synapse differentiation inducing 1 |
| TCP10 | t-complex 10 |
| THSD7A | thrombospondin, type I, domain containing 7A |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 |
| TRAF1 | TNF receptor-associated factor 1 |
| TRD | T cell receptor delta locus |
| TRIM10 | tripartite motif containing 10 |
| TRIM3 | tripartite motif containing 3 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VPS9D1 | VPS9 domain containing 1 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF384 | zinc finger protein 384 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BLMH | bleomycin hydrolase |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| CCNJ | cyclin J |
| CENPE | centromere protein E, 312kDa |
| CEP97 | centrosomal protein 97kDa |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CXORF56 | chromosome X open reading frame 56 |
| CYBRD1 | cytochrome b reductase 1 |
| DARS2 | aspartyl-tRNA synthetase 2, mitochondrial |
| DEAF1 | DEAF1 transcription factor |
| DENND1A | DENN/MADD domain containing 1A |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| ELP5 | elongator acetyltransferase complex subunit 5 |
| EML4 | echinoderm microtubule associated protein like 4 |
| EXOC5 | exocyst complex component 5 |
| FAR2 | fatty acyl CoA reductase 2 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GTF2I | general transcription factor IIi |
| ICK | intestinal cell (MAK-like) kinase |
| IREB2 | iron-responsive element binding protein 2 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| LMAN1 | lectin, mannose-binding, 1 |
| LMNB1 | lamin B1 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| METTL16 | methyltransferase like 16 |
| MOSPD3 | motile sperm domain containing 3 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NMD3 | NMD3 ribosome export adaptor |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NUS1P3 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3 |
| PARPBP | PARP1 binding protein |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PGM3 | phosphoglucomutase 3 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PLS1 | plastin 1 |
| PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha |
| PRMT1 | protein arginine methyltransferase 1 |
| PSAT1 | phosphoserine aminotransferase 1 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RAB23 | RAB23, member RAS oncogene family |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RARS | arginyl-tRNA synthetase |
| RNF122 | ring finger protein 122 |
| RNF146 | ring finger protein 146 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPE | ribulose-5-phosphate-3-epimerase |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPP14 | ribonuclease P/MRP 14kDa subunit |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SERPINB10 | serpin peptidase inhibitor, clade B (ovalbumin), member 10 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH3YL1 | SH3 and SYLF domain containing 1 |
| SHPK | sedoheptulokinase |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STX5 | syntaxin 5 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TCTN1 | tectonic family member 1 |
| TEC | tec protein tyrosine kinase |
| TMEM185B | transmembrane protein 185B |
| TRIM16 | tripartite motif containing 16 |
| UGGT1 | UDP-glucose glycoprotein glucosyltransferase 1 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| XPO7 | exportin 7 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF197 | zinc finger protein 197 |
| ZNF215 | zinc finger protein 215 |
| ZNF250 | zinc finger protein 250 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF665 | zinc finger protein 665 |
| ZNF675 | zinc finger protein 675 |
| ZW10 | zw10 kinetochore protein |
