| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the picrotoxinin-2816 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit |
| CAMK2B | calcium/calmodulin-dependent protein kinase II beta |
| CAPN9 | calpain 9 |
| CD200 | CD200 molecule |
| CD8A | CD8a molecule |
| CDH8 | cadherin 8, type 2 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CGA | glycoprotein hormones, alpha polypeptide |
| CORO7 | coronin 7 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CTRC | chymotrypsin C (caldecrin) |
| CTSF | cathepsin F |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DICER1 | dicer 1, ribonuclease type III |
| DNAH17 | dynein, axonemal, heavy chain 17 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 |
| ESR1 | estrogen receptor 1 |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| GAD2 | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) |
| GRPR | gastrin-releasing peptide receptor |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSN | gelsolin |
| HEMK1 | HemK methyltransferase family member 1 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HNF1B | HNF1 homeobox B |
| HOXA1 | homeobox A1 |
| HPX | hemopexin |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IFNA17 | interferon, alpha 17 |
| IL2 | interleukin 2 |
| IL23A | interleukin 23, alpha subunit p19 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRT15 | keratin 15, type I |
| LEPR | leptin receptor |
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 |
| LMF2 | lipase maturation factor 2 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MAGOH2P | mago-nashi homolog 2, pseudogene |
| MAP2K7 | mitogen-activated protein kinase kinase 7 |
| MCAM | melanoma cell adhesion molecule |
| MED16 | mediator complex subunit 16 |
| MED25 | mediator complex subunit 25 |
| MMP25 | matrix metallopeptidase 25 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NEB | nebulin |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PLLP | plasmolipin |
| POU4F1 | POU class 4 homeobox 1 |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRF1 | perforin 1 (pore forming protein) |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLN | sarcolipin |
| SPATA2L | spermatogenesis associated 2-like |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPRR1A | small proline-rich protein 1A |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| ST7L | suppression of tumorigenicity 7 like |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| TBXA2R | thromboxane A2 receptor |
| THBS3 | thrombospondin 3 |
| TMC6 | transmembrane channel-like 6 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRPM3 | transient receptor potential cation channel, subfamily M, member 3 |
| TUBA3C | tubulin, alpha 3c |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| ULBP1 | UL16 binding protein 1 |
| XDH | xanthine dehydrogenase |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF205 | zinc finger protein 205 |
| ZYX | zyxin |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| AFAP1 | actin filament associated protein 1 |
| AFF4 | AF4/FMR2 family, member 4 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCNO | cyclin O |
| CCNT1 | cyclin T1 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CENPQ | centromere protein Q |
| CHKB | choline kinase beta |
| CHMP6 | charged multivesicular body protein 6 |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CLDN9 | claudin 9 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM160B2 | family with sequence similarity 160, member B2 |
| FAM188A | family with sequence similarity 188, member A |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FANCC | Fanconi anemia, complementation group C |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLCN | folliculin |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GAA | glucosidase, alpha; acid |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GPATCH2L | G patch domain containing 2-like |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| LAMA3 | laminin, alpha 3 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| METTL22 | methyltransferase like 22 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| MYBBP1A | MYB binding protein (P160) 1a |
| MYO1D | myosin ID |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PHF21A | PHD finger protein 21A |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) |
| PLA2G10 | phospholipase A2, group X |
| PLA2G12A | phospholipase A2, group XIIA |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLD2 | phospholipase D2 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| QPRT | quinolinate phosphoribosyltransferase |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RPIA | ribose 5-phosphate isomerase A |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SCRN3 | secernin 3 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMTN | smoothelin |
| SNX16 | sorting nexin 16 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TARP | TCR gamma alternate reading frame protein |
| TEP1 | telomerase-associated protein 1 |
| TMEM120B | transmembrane protein 120B |
| TTC33 | tetratricopeptide repeat domain 33 |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| UNC119 | unc-119 homolog (C. elegans) |
| WDR33 | WD repeat domain 33 |
| YY2 | YY2 transcription factor |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF324 | zinc finger protein 324 |
| ZNF532 | zinc finger protein 532 |
| ZNF696 | zinc finger protein 696 |
| ZNF813 | zinc finger protein 813 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
