| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the picrotoxinin-4260 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABAT | 4-aminobutyrate aminotransferase |
| ABCA12 | ATP-binding cassette, sub-family A (ABC1), member 12 |
| ABO | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) |
| ACRV1 | acrosomal vesicle protein 1 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADRA1A | adrenoceptor alpha 1A |
| AFF2 | AF4/FMR2 family, member 2 |
| AGXT | alanine-glyoxylate aminotransferase |
| ALPI | alkaline phosphatase, intestinal |
| AP4E1 | adaptor-related protein complex 4, epsilon 1 subunit |
| ARSD | arylsulfatase D |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| C16ORF70 | chromosome 16 open reading frame 70 |
| C1QL1 | complement component 1, q subcomponent-like 1 |
| CNTNAP2 | contactin associated protein-like 2 |
| COL9A3 | collagen, type IX, alpha 3 |
| CSN2 | casein beta |
| CSPG4 | chondroitin sulfate proteoglycan 4 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DSC1 | desmocollin 1 |
| FAM149A | family with sequence similarity 149, member A |
| FOXD3 | forkhead box D3 |
| FOXN3 | forkhead box N3 |
| FSCN2 | fascin actin-bundling protein 2, retinal |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) |
| GPR135 | G protein-coupled receptor 135 |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| HGD | homogentisate 1,2-dioxygenase |
| HIST1H2BL | histone cluster 1, H2bl |
| HRG | histidine-rich glycoprotein |
| HSD3B2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 |
| IAPP | islet amyloid polypeptide |
| IGL | immunoglobulin lambda locus |
| IL1RN | interleukin 1 receptor antagonist |
| INS | insulin |
| IQCA1 | IQ motif containing with AAA domain 1 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) |
| KHDRBS2 | KH domain containing, RNA binding, signal transduction associated 2 |
| KRTAP9-9 | keratin associated protein 9-9 |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 |
| LARP4B | La ribonucleoprotein domain family, member 4B |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| METTL7A | methyltransferase like 7A |
| MUC3B | mucin 3B, cell surface associated |
| NEK9 | NIMA-related kinase 9 |
| NF1 | neurofibromin 1 |
| NPPB | natriuretic peptide B |
| NPR1 | natriuretic peptide receptor 1 |
| NRXN3 | neurexin 3 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| OLFM4 | olfactomedin 4 |
| OPRD1 | opioid receptor, delta 1 |
| PACRG | PARK2 co-regulated |
| PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 |
| PAK7 | p21 protein (Cdc42/Rac)-activated kinase 7 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLA2G5 | phospholipase A2, group V |
| PLN | phospholamban |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRRX2 | paired related homeobox 2 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTTG2 | pituitary tumor-transforming 2 |
| RAG2 | recombination activating gene 2 |
| RASA3 | RAS p21 protein activator 3 |
| RASSF4 | Ras association (RalGDS/AF-6) domain family member 4 |
| RBM12B | RNA binding motif protein 12B |
| RGS14 | regulator of G-protein signaling 14 |
| RHO | rhodopsin |
| SAGE1 | sarcoma antigen 1 |
| SEC14L4 | SEC14-like 4 (S. cerevisiae) |
| SFRP5 | secreted frizzled-related protein 5 |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC22A2 | solute carrier family 22 (organic cation transporter), member 2 |
| SLC34A1 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 1 |
| SOX5 | SRY (sex determining region Y)-box 5 |
| SPAG6 | sperm associated antigen 6 |
| SVIL | supervillin |
| SYCP1 | synaptonemal complex protein 1 |
| SYT13 | synaptotagmin XIII |
| TF | transferrin |
| TJP3 | tight junction protein 3 |
| TLE2 | transducin-like enhancer of split 2 |
| TMEM59L | transmembrane protein 59-like |
| TNK2 | tyrosine kinase, non-receptor, 2 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRD | T cell receptor delta locus |
| TRGV5 | T cell receptor gamma variable 5 |
| TRIM31 | tripartite motif containing 31 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| ZMAT4 | zinc finger, matrin-type 4 |
| ZNF484 | zinc finger protein 484 |
| ZNF814 | zinc finger protein 814 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BNC1 | basonuclin 1 |
| C11ORF30 | chromosome 11 open reading frame 30 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CCDC85C | coiled-coil domain containing 85C |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CEP112 | centrosomal protein 112kDa |
| CIDEB | cell death-inducing DFFA-like effector b |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| COCH | cochlin |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DENND4A | DENN/MADD domain containing 4A |
| DNM3 | dynamin 3 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| EDN1 | endothelin 1 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| FAM184A | family with sequence similarity 184, member A |
| FAM186A | family with sequence similarity 186, member A |
| FAM69A | family with sequence similarity 69, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FOXO1 | forkhead box O1 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GID4 | GID complex subunit 4 |
| GPATCH2L | G patch domain containing 2-like |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIST1H1D | histone cluster 1, H1d |
| HMHA1 | histocompatibility (minor) HA-1 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KIAA1462 | KIAA1462 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMO7 | LIM domain 7 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LOC730101 | uncharacterized LOC730101 |
| LTBP2 | latent transforming growth factor beta binding protein 2 |
| MBTD1 | mbt domain containing 1 |
| MYO15A | myosin XVA |
| NDP | Norrie disease (pseudoglioma) |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OSR2 | odd-skipped related transciption factor 2 |
| PALMD | palmdelphin |
| PER3 | period circadian clock 3 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLA2G15 | phospholipase A2, group XV |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PLXNB3 | plexin B3 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRPH | peripherin |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SHROOM2 | shroom family member 2 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPEG | SPEG complex locus |
| TAGLN3 | transgelin 3 |
| TEX40 | testis expressed 40 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM132A | transmembrane protein 132A |
| TMEM242 | transmembrane protein 242 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TSPAN8 | tetraspanin 8 |
| TXLNG | taxilin gamma |
| UGT8 | UDP glycosyltransferase 8 |
| XPA | xeroderma pigmentosum, complementation group A |
| YY2 | YY2 transcription factor |
| ZNF10 | zinc finger protein 10 |
| ZNF273 | zinc finger protein 273 |
| ZNF286A | zinc finger protein 286A |
| ZNF33B | zinc finger protein 33B |
| ZNF34 | zinc finger protein 34 |
| ZNF492 | zinc finger protein 492 |
| ZNF76 | zinc finger protein 76 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF778 | zinc finger protein 778 |