pilocarpine-5341 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the pilocarpine-5341 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABHD6 abhydrolase domain containing 6
ANKRD26 ankyrin repeat domain 26
ARC activity-regulated cytoskeleton-associated protein
ARL2BP ADP-ribosylation factor-like 2 binding protein
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
B4GALT7 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7
BAHCC1 BAH domain and coiled-coil containing 1
BAIAP2 BAI1-associated protein 2
BMP4 bone morphogenetic protein 4
C21ORF2 chromosome 21 open reading frame 2
CACTIN cactin, spliceosome C complex subunit
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CD58 CD58 molecule
CEP164 centrosomal protein 164kDa
CHKB choline kinase beta
CHPF2 chondroitin polymerizing factor 2
CNOT4 CCR4-NOT transcription complex, subunit 4
CPTP ceramide-1-phosphate transfer protein
DGAT1 diacylglycerol O-acyltransferase 1
DMTN dematin actin binding protein
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERN2 endoplasmic reticulum to nucleus signaling 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GSTM1 glutathione S-transferase mu 1
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HCFC1 host cell factor C1
HIST1H2AJ histone cluster 1, H2aj
HLA-DMA major histocompatibility complex, class II, DM alpha
HPS4 Hermansky-Pudlak syndrome 4
IFIH1 interferon induced with helicase C domain 1
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL27RA interleukin 27 receptor, alpha
INO80D INO80 complex subunit D
IPO8 importin 8
IRF2 interferon regulatory factor 2
LOC399491
LRRC20 leucine rich repeat containing 20
MAP4 microtubule-associated protein 4
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MNX1 motor neuron and pancreas homeobox 1
MUC1 mucin 1, cell surface associated
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDRG4 NDRG family member 4
NEK11 NIMA-related kinase 11
NMT2 N-myristoyltransferase 2
NNT nicotinamide nucleotide transhydrogenase
PCGF2 polycomb group ring finger 2
PCGF3 polycomb group ring finger 3
PDAP1 PDGFA associated protein 1
PDCD2 programmed cell death 2
PHC1 polyhomeotic homolog 1 (Drosophila)
POFUT1 protein O-fucosyltransferase 1
PPP6R2 protein phosphatase 6, regulatory subunit 2
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
RASAL2 RAS protein activator like 2
RECQL5 RecQ protein-like 5
RGS10 regulator of G-protein signaling 10
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF31 ring finger protein 31
RPAP2 RNA polymerase II associated protein 2
RPL10 ribosomal protein L10
S100A4 S100 calcium binding protein A4
S100A8 S100 calcium binding protein A8
SCRN3 secernin 3
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFTPC surfactant protein C
SFXN3 sideroflexin 3
SH3BP2 SH3-domain binding protein 2
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
SOCS2 suppressor of cytokine signaling 2
SOX12 SRY (sex determining region Y)-box 12
SSPN sarcospan
SUGP1 SURP and G patch domain containing 1
TFIP11 tuftelin interacting protein 11
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM62 transmembrane protein 62
TRAK1 trafficking protein, kinesin binding 1
TRIM2 tripartite motif containing 2
TRIM21 tripartite motif containing 21
TUBGCP4 tubulin, gamma complex associated protein 4
USP22 ubiquitin specific peptidase 22
ZBTB17 zinc finger and BTB domain containing 17
ZBTB40 zinc finger and BTB domain containing 40
ZC3H12A zinc finger CCCH-type containing 12A
ZER1 zyg-11 related, cell cycle regulator
ZNF350 zinc finger protein 350
ZNF573 zinc finger protein 573
ZNF589 zinc finger protein 589
ZNF750 zinc finger protein 750
ZNRD1-AS1 ZNRD1 antisense RNA 1

decreased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ANXA2P3 annexin A2 pseudogene 3
ARMC6 armadillo repeat containing 6
ASPHD1 aspartate beta-hydroxylase domain containing 1
AVEN apoptosis, caspase activation inhibitor
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
CAMKMT calmodulin-lysine N-methyltransferase
CARD8 caspase recruitment domain family, member 8
CBY1 chibby homolog 1 (Drosophila)
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK20 cyclin-dependent kinase 20
CEP97 centrosomal protein 97kDa
CHMP7 charged multivesicular body protein 7
CHST10 carbohydrate sulfotransferase 10
CNGB3 cyclic nucleotide gated channel beta 3
CRELD1 cysteine-rich with EGF-like domains 1
CTNNBIP1 catenin, beta interacting protein 1
CUL9 cullin 9
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DENND4A DENN/MADD domain containing 4A
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERF Ets2 repressor factor
ETAA1 Ewing tumor-associated antigen 1
FAM155B family with sequence similarity 155, member B
FAM222B family with sequence similarity 222, member B
FAN1 FANCD2/FANCI-associated nuclease 1
FAR2 fatty acyl CoA reductase 2
FBRS fibrosin
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCHO1 FCH domain only 1
FLCN folliculin
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
FYCO1 FYVE and coiled-coil domain containing 1
GPX2 glutathione peroxidase 2
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2I general transcription factor IIi
HIRA histone cell cycle regulator
HIST1H1E histone cluster 1, H1e
HIST2H2AA3 histone cluster 2, H2aa3
HOXC10 homeobox C10
IFI6 interferon, alpha-inducible protein 6
IFT22 intraflagellar transport 22
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF6 interferon regulatory factor 6
JUNB jun B proto-oncogene
KCTD20 potassium channel tetramerization domain containing 20
KDM5C lysine (K)-specific demethylase 5C
KRT13 keratin 13, type I
LOC257152 uncharacterized LOC257152
LOC642236 FSHD region gene 1 pseudogene
LRRC8E leucine rich repeat containing 8 family, member E
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBIP MAP3K12 binding inhibitory protein 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL8 methyltransferase like 8
NDE1 nudE neurodevelopment protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPFFR1 neuropeptide FF receptor 1
ORC1 origin recognition complex, subunit 1
PER3 period circadian clock 3
PGPEP1 pyroglutamyl-peptidase I
PILRB paired immunoglobin-like type 2 receptor beta
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPAP2C phosphatidic acid phosphatase type 2C
PRPH peripherin
PVRL3 poliovirus receptor-related 3
QTRT1 queuine tRNA-ribosyltransferase 1
RNF126P1 ring finger protein 126 pseudogene 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SHARPIN SHANK-associated RH domain interactor
SLC27A6 solute carrier family 27 (fatty acid transporter), member 6
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SNX16 sorting nexin 16
SPANXC SPANX family, member C
SPRYD7 SPRY domain containing 7
STX17 syntaxin 17
TAOK1 TAO kinase 1
THBS3 thrombospondin 3
THRAP3 thyroid hormone receptor associated protein 3
TMSB15A thymosin beta 15a
TPST1 tyrosylprotein sulfotransferase 1
TRAIP TRAF interacting protein
TUBA3C tubulin, alpha 3c
UBQLN4 ubiquilin 4
USP27X ubiquitin specific peptidase 27, X-linked
ZNF134 zinc finger protein 134
ZNF141 zinc finger protein 141
ZNF184 zinc finger protein 184
ZNF580 zinc finger protein 580
ZNF639 zinc finger protein 639
ZNF696 zinc finger protein 696