pimethixene Gene Set

Dataset LINCS L1000 CMAP Chemical Perturbation Consensus Signatures
Category transcriptomics
Type small molecule perturbation
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Genes

32 genes differentially expressed following the pimethixene small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
EPHB2 EPH receptor B2 7.18078
GLI2 GLI family zinc finger 2 4.61658
CANT1 calcium activated nucleotidase 1 3.87402
PTCH2 patched 2 3.84352
TCHH trichohyalin 3.77491
ECE2 endothelin converting enzyme 2 3.48589
SLC43A3 solute carrier family 43, member 3 3.42154
CSRP1 cysteine and glycine-rich protein 1 3.4174
NOX1 NADPH oxidase 1 3.28037
EDA ectodysplasin A 3.27889
PXDC1 PX domain containing 1 3.24757
PRKCQ protein kinase C, theta 3.22935
SORBS3 sorbin and SH3 domain containing 3 3.19688
CCN6 cellular communication network factor 6 3.19179
C3ORF36 chromosome 3 open reading frame 36 3.14573
RUBCNL rubicon like autophagy enhancer 3.13912
SOX9 SRY (sex determining region Y)-box 9 3.12988
KIF16B kinesin family member 16B 3.12065
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 3.07629
QKI QKI, KH domain containing, RNA binding 3.07493
KRT31 keratin 31, type I 3.02092

decreased expression

Symbol Name Standardized Value
KLHDC2 kelch domain containing 2 -5.56541
GSTZ1 glutathione S-transferase zeta 1 -4.28513
PRPF4 pre-mRNA processing factor 4 -4.15887
SNAP25 synaptosomal-associated protein, 25kDa -3.93277
GLE1 GLE1 RNA export mediator -3.66249
TATDN2 TatD DNase domain containing 2 -3.56219
RBM34 RNA binding motif protein 34 -3.27358
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit -3.15405
CTNNA2 catenin (cadherin-associated protein), alpha 2 -3.14884
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit -3.14369
MSL2 male-specific lethal 2 homolog (Drosophila) -3.06186