pimozide-1562 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the pimozide-1562 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4
ACTC1 actin, alpha, cardiac muscle 1
AFF2 AF4/FMR2 family, member 2
ANKMY1 ankyrin repeat and MYND domain containing 1
BCL3 B-cell CLL/lymphoma 3
CASD1 CAS1 domain containing 1
CCDC64 coiled-coil domain containing 64
CCPG1 cell cycle progression 1
CD2BP2 CD2 (cytoplasmic tail) binding protein 2
CLDN10 claudin 10
CLEC11A C-type lectin domain family 11, member A
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CUX1 cut-like homeobox 1
DEAF1 DEAF1 transcription factor
DEFB1 defensin, beta 1
DIO2 deiodinase, iodothyronine, type II
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DSN1 DSN1, MIS12 kinetochore complex component
DUSP2 dual specificity phosphatase 2
EGR4 early growth response 4
ELK1 ELK1, member of ETS oncogene family
ELN elastin
EMX1 empty spiracles homeobox 1
ENOX2 ecto-NOX disulfide-thiol exchanger 2
EPS8L1 EPS8-like 1
FAM153A family with sequence similarity 153, member A
FKBP9 FK506 binding protein 9, 63 kDa
FLII flightless I homolog (Drosophila)
FMOD fibromodulin
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GABARAPL1 GABA(A) receptor-associated protein like 1
GHRHR growth hormone releasing hormone receptor
GM2A GM2 ganglioside activator
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPR183 G protein-coupled receptor 183
HDAC7 histone deacetylase 7
HMGA2 high mobility group AT-hook 2
IL24 interleukin 24
JAG1 jagged 1
LBP lipopolysaccharide binding protein
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LSG1 large 60S subunit nuclear export GTPase 1
MAST2 microtubule associated serine/threonine kinase 2
METTL5 methyltransferase like 5
MOB3B MOB kinase activator 3B
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MYL10 myosin, light chain 10, regulatory
MYO1A myosin IA
MYO1C myosin IC
NDE1 nudE neurodevelopment protein 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PCDH17 protocadherin 17
PDCD2 programmed cell death 2
PDGFA platelet-derived growth factor alpha polypeptide
PHF8 PHD finger protein 8
PHOX2B paired-like homeobox 2b
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PLCB2 phospholipase C, beta 2
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PLSCR1 phospholipid scramblase 1
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PVR poliovirus receptor
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RARB retinoic acid receptor, beta
RIMS2 regulating synaptic membrane exocytosis 2
RIN3 Ras and Rab interactor 3
RTEL1 regulator of telomere elongation helicase 1
RUNDC3A RUN domain containing 3A
SAG S-antigen; retina and pineal gland (arrestin)
SAT1 spermidine/spermine N1-acetyltransferase 1
SDC2 syndecan 2
SGK1 serum/glucocorticoid regulated kinase 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SIK2 salt-inducible kinase 2
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SOCS3 suppressor of cytokine signaling 3
SPN sialophorin
SRSF11 serine/arginine-rich splicing factor 11
TCP10L t-complex 10-like
TCTN2 tectonic family member 2
THTPA thiamine triphosphatase
TM2D1 TM2 domain containing 1
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TP53I11 tumor protein p53 inducible protein 11
TP63 tumor protein p63
TUBA4B tubulin, alpha 4b
TUFT1 tuftelin 1
UBOX5 U-box domain containing 5
UNC13B unc-13 homolog B (C. elegans)
USF2 upstream transcription factor 2, c-fos interacting
XPA xeroderma pigmentosum, complementation group A
ZFR2 zinc finger RNA binding protein 2
ZNF451 zinc finger protein 451
ZNF701 zinc finger protein 701

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
ALDOC aldolase C, fructose-bisphosphate
ANKZF1 ankyrin repeat and zinc finger domain containing 1
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ASUN asunder spermatogenesis regulator
BABAM1 BRISC and BRCA1 A complex member 1
BMS1 BMS1 ribosome biogenesis factor
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
CCL2 chemokine (C-C motif) ligand 2
CD69 CD69 molecule
CDK8 cyclin-dependent kinase 8
CEP85 centrosomal protein 85kDa
CHST10 carbohydrate sulfotransferase 10
CLTCL1 clathrin, heavy chain-like 1
CNPY3 canopy FGF signaling regulator 3
CYTIP cytohesin 1 interacting protein
DEF8 differentially expressed in FDCP 8 homolog (mouse)
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
DPF2 D4, zinc and double PHD fingers family 2
EMD emerin
ERCC2 excision repair cross-complementation group 2
ERO1L ERO1-like (S. cerevisiae)
FAM114A2 family with sequence similarity 114, member A2
FAM188A family with sequence similarity 188, member A
FAM192A family with sequence similarity 192, member A
FAM63A family with sequence similarity 63, member A
FBXO5 F-box protein 5
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
GINS2 GINS complex subunit 2 (Psf2 homolog)
GSTM3 glutathione S-transferase mu 3 (brain)
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa
HILPDA hypoxia inducible lipid droplet-associated
HMG20A high mobility group 20A
HPCAL1 hippocalcin-like 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB1 heat shock 27kDa protein 1
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial
KDM3A lysine (K)-specific demethylase 3A
LIAS lipoic acid synthetase
LPAR6 lysophosphatidic acid receptor 6
MAPKBP1 mitogen-activated protein kinase binding protein 1
MBIP MAP3K12 binding inhibitory protein 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MRPL28 mitochondrial ribosomal protein L28
MRPS28 mitochondrial ribosomal protein S28
MXI1 MAX interactor 1, dimerization protein
MYLIP myosin regulatory light chain interacting protein
NCF1C neutrophil cytosolic factor 1C pseudogene
NDRG1 N-myc downstream regulated 1
NREP neuronal regeneration related protein
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PBX3 pre-B-cell leukemia homeobox 3
PCOLCE2 procollagen C-endopeptidase enhancer 2
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1
PRKCD protein kinase C, delta
PRRC1 proline-rich coiled-coil 1
PRTN3 proteinase 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RNMTL1 RNA methyltransferase like 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPP14 ribonuclease P/MRP 14kDa subunit
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
RRAGA Ras-related GTP binding A
RRP1 ribosomal RNA processing 1
S100A12 S100 calcium binding protein A12
S100A6 S100 calcium binding protein A6
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLN sarcolipin
SNX17 sorting nexin 17
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STC2 stanniocalcin 2
STRA13 stimulated by retinoic acid 13
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TBL3 transducin (beta)-like 3
TMEM11 transmembrane protein 11
TMEM45A transmembrane protein 45A
TMEM50A transmembrane protein 50A
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSLIG2 tRNA splicing ligase complex subunit 2
VLDLR very low density lipoprotein receptor
XYLT1 xylosyltransferase I
YARS tyrosyl-tRNA synthetase
ZNF395 zinc finger protein 395
ZNF804A zinc finger protein 804A