| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the pimozide-7132 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 |
| ATF3 | activating transcription factor 3 |
| ATP6V0E1 | ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| C11ORF71 | chromosome 11 open reading frame 71 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 |
| CD58 | CD58 molecule |
| CENPJ | centromere protein J |
| CLEC2B | C-type lectin domain family 2, member B |
| COPA | coatomer protein complex, subunit alpha |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYB561 | cytochrome b561 |
| CYBA | cytochrome b-245, alpha polypeptide |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DTNA | dystrobrevin, alpha |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EFNA5 | ephrin-A5 |
| EGF | epidermal growth factor |
| EGFR | epidermal growth factor receptor |
| EML3 | echinoderm microtubule associated protein like 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ESR1 | estrogen receptor 1 |
| FER1L4 | fer-1-like family member 4, pseudogene (functional) |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GATA3 | GATA binding protein 3 |
| GK | glycerol kinase |
| GLG1 | golgi glycoprotein 1 |
| GOLGA2 | golgin A2 |
| H2AFX | H2A histone family, member X |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 |
| HDAC9 | histone deacetylase 9 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HINFP | histone H4 transcription factor |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOMER3 | homer scaffolding protein 3 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IFI44 | interferon-induced protein 44 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| KLF6 | Kruppel-like factor 6 |
| KLHL24 | kelch-like family member 24 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| METTL7A | methyltransferase like 7A |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MX1 | MX dynamin-like GTPase 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NIPBL | Nipped-B homolog (Drosophila) |
| NLRX1 | NLR family member X1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PEX5 | peroxisomal biogenesis factor 5 |
| PGAP1 | post-GPI attachment to proteins 1 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLXNB1 | plexin B1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PNPLA4 | patatin-like phospholipase domain containing 4 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RGS14 | regulator of G-protein signaling 14 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SHPK | sedoheptulokinase |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSH3 | slingshot protein phosphatase 3 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| SYT1 | synaptotagmin I |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TRAPPC10 | trafficking protein particle complex 10 |
| TRIB3 | tribbles pseudokinase 3 |
| TSPAN1 | tetraspanin 1 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| YY2 | YY2 transcription factor |
| ZFPL1 | zinc finger protein-like 1 |
| ZNF467 | zinc finger protein 467 |
| ZNF75D | zinc finger protein 75D |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ASS1 | argininosuccinate synthase 1 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BAX | BCL2-associated X protein |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL2A1 | BCL2-related protein A1 |
| BCL9 | B-cell CLL/lymphoma 9 |
| C19ORF54 | chromosome 19 open reading frame 54 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CBR4 | carbonyl reductase 4 |
| CCNJL | cyclin J-like |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EVPL | envoplakin |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FANCE | Fanconi anemia, complementation group E |
| FCHO1 | FCH domain only 1 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FHOD1 | formin homology 2 domain containing 1 |
| FHOD3 | formin homology 2 domain containing 3 |
| GAB2 | GRB2-associated binding protein 2 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GSR | glutathione reductase |
| HELLS | helicase, lymphoid-specific |
| HIRA | histone cell cycle regulator |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| HOXC10 | homeobox C10 |
| IL4R | interleukin 4 receptor |
| KRT8P12 | keratin 8 pseudogene 12 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MOB3B | MOB kinase activator 3B |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MON1B | MON1 secretory trafficking family member B |
| MYLK | myosin light chain kinase |
| MYNN | myoneurin |
| NCS1 | neuronal calcium sensor 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NHLRC2 | NHL repeat containing 2 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| ODF2 | outer dense fiber of sperm tails 2 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRMT7 | protein arginine methyltransferase 7 |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RAB4B | RAB4B, member RAS oncogene family |
| RBL1 | retinoblastoma-like 1 |
| RECQL4 | RecQ protein-like 4 |
| RINT1 | RAD50 interactor 1 |
| ROGDI | rogdi homolog (Drosophila) |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC41A3 | solute carrier family 41, member 3 |
| SLTM | SAFB-like, transcription modulator |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STK16 | serine/threonine kinase 16 |
| TBC1D10B | TBC1 domain family, member 10B |
| TEAD3 | TEA domain family member 3 |
| TGIF2 | TGFB-induced factor homeobox 2 |
| TGS1 | trimethylguanosine synthase 1 |
| THBS3 | thrombospondin 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TRAIP | TRAF interacting protein |
| TRIM26 | tripartite motif containing 26 |
| UNKL | unkempt family zinc finger-like |
| USP6NL | USP6 N-terminal like |
| WBSCR16 | Williams-Beuren syndrome chromosome region 16 |
| WDR41 | WD repeat domain 41 |
| WWC2 | WW and C2 domain containing 2 |
| ZNF787 | zinc finger protein 787 |
| ZNF813 | zinc finger protein 813 |