| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the pinacidil-5456 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADAM12 | ADAM metallopeptidase domain 12 |
| ADAMDEC1 | ADAM-like, decysin 1 |
| AEBP1 | AE binding protein 1 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| AMT | aminomethyltransferase |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APAF1 | apoptotic peptidase activating factor 1 |
| ATP11A | ATPase, class VI, type 11A |
| ATP6V1B1 | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 |
| BIN1 | bridging integrator 1 |
| BRD4 | bromodomain containing 4 |
| CADM4 | cell adhesion molecule 4 |
| CALML3 | calmodulin-like 3 |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CD1A | CD1a molecule |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| CDK19 | cyclin-dependent kinase 19 |
| CDK6 | cyclin-dependent kinase 6 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CNTNAP1 | contactin associated protein 1 |
| CREBBP | CREB binding protein |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CXCR1 | chemokine (C-X-C motif) receptor 1 |
| CYP4F12 | cytochrome P450, family 4, subfamily F, polypeptide 12 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| EFNB3 | ephrin-B3 |
| EGR2 | early growth response 2 |
| EML2 | echinoderm microtubule associated protein like 2 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 |
| FHL1 | four and a half LIM domains 1 |
| GC | group-specific component (vitamin D binding protein) |
| GK3P | glycerol kinase 3 pseudogene |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPR162 | G protein-coupled receptor 162 |
| HGFAC | HGF activator |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HOXD1 | homeobox D1 |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| ICA1 | islet cell autoantigen 1, 69kDa |
| ITGB7 | integrin, beta 7 |
| ITK | IL2-inducible T-cell kinase |
| KCNIP1 | Kv channel interacting protein 1 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KHSRP | KH-type splicing regulatory protein |
| LATS1 | large tumor suppressor kinase 1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MC5R | melanocortin 5 receptor |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MEF2C | myocyte enhancer factor 2C |
| MLANA | melan-A |
| MRPL20 | mitochondrial ribosomal protein L20 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NF1 | neurofibromin 1 |
| NIPSNAP3B | nipsnap homolog 3B (C. elegans) |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| P2RY4 | pyrimidinergic receptor P2Y, G-protein coupled, 4 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PEG3 | paternally expressed 3 |
| PGAP3 | post-GPI attachment to proteins 3 |
| PIP | prolactin-induced protein |
| PON3 | paraoxonase 3 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PRM1 | protamine 1 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRH | protein tyrosine phosphatase, receptor type, H |
| RAB40C | RAB40C, member RAS oncogene family |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RGS7 | regulator of G-protein signaling 7 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RTN1 | reticulon 1 |
| RUNX3 | runt-related transcription factor 3 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC7A10 | solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPAG8 | sperm associated antigen 8 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TNXB | tenascin XB |
| TULP2 | tubby like protein 2 |
| UTS2 | urotensin 2 |
| VN1R1 | vomeronasal 1 receptor 1 |
| XYLB | xylulokinase homolog (H. influenzae) |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF750 | zinc finger protein 750 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ALPK1 | alpha-kinase 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BBS10 | Bardet-Biedl syndrome 10 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CAPN5 | calpain 5 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD83 | CD83 molecule |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLGN | calmegin |
| CLSPN | claspin |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CST6 | cystatin E/M |
| DCAF10 | DDB1 and CUL4 associated factor 10 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EDAR | ectodysplasin A receptor |
| EMID1 | EMI domain containing 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM212B | family with sequence similarity 212, member B |
| FER | fer (fps/fes related) tyrosine kinase |
| FLT4 | fms-related tyrosine kinase 4 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GAMT | guanidinoacetate N-methyltransferase |
| GLB1L | galactosidase, beta 1-like |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H2AK | histone cluster 1, H2ak |
| HIST1H4C | histone cluster 1, H4c |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL15RA | interleukin 15 receptor, alpha |
| ITGA10 | integrin, alpha 10 |
| KIAA0754 | KIAA0754 |
| KIAA0894 | KIAA0894 protein |
| KLHL28 | kelch-like family member 28 |
| KLK5 | kallikrein-related peptidase 5 |
| KRT13 | keratin 13, type I |
| LIN7A | lin-7 homolog A (C. elegans) |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MATK | megakaryocyte-associated tyrosine kinase |
| MED15 | mediator complex subunit 15 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MUC3A | mucin 3A, cell surface associated |
| NDE1 | nudE neurodevelopment protein 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOL10 | nucleolar protein 10 |
| NRSN2 | neurensin 2 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OSMR | oncostatin M receptor |
| PDE8B | phosphodiesterase 8B |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLA2G3 | phospholipase A2, group III |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNF39 | ring finger protein 39 |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPRYD7 | SPRY domain containing 7 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STEAP4 | STEAP family member 4 |
| TAOK1 | TAO kinase 1 |
| TEP1 | telomerase-associated protein 1 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TRIM21 | tripartite motif containing 21 |
| TUBG2 | tubulin, gamma 2 |
| TWISTNB | TWIST neighbor |
| UPP1 | uridine phosphorylase 1 |
| USB1 | U6 snRNA biogenesis 1 |
| USP6 | ubiquitin specific peptidase 6 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZNF189 | zinc finger protein 189 |
| ZNF324 | zinc finger protein 324 |
| ZNF480 | zinc finger protein 480 |
| ZNF652 | zinc finger protein 652 |
| ZNF862 | zinc finger protein 862 |
