| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the pinacidil-6356 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) |
| AKAP5 | A kinase (PRKA) anchor protein 5 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| APOC4 | apolipoprotein C-IV |
| ARL3 | ADP-ribosylation factor-like 3 |
| ARRB2 | arrestin, beta 2 |
| ATP13A2 | ATPase type 13A2 |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| ATP9A | ATPase, class II, type 9A |
| BCL2 | B-cell CLL/lymphoma 2 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BMP1 | bone morphogenetic protein 1 |
| BNIP1 | BCL2/adenovirus E1B 19kDa interacting protein 1 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CALD1 | caldesmon 1 |
| CD82 | CD82 molecule |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CIB2 | calcium and integrin binding family member 2 |
| CISH | cytokine inducible SH2-containing protein |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EIF1 | eukaryotic translation initiation factor 1 |
| ELL | elongation factor RNA polymerase II |
| EMP1 | epithelial membrane protein 1 |
| ERCC5 | excision repair cross-complementation group 5 |
| FBXO31 | F-box protein 31 |
| FGF8 | fibroblast growth factor 8 (androgen-induced) |
| FOXO1 | forkhead box O1 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GOLGA2 | golgin A2 |
| GON4L | gon-4-like (C. elegans) |
| HIST1H2AI | histone cluster 1, H2ai |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXA11 | homeobox A11 |
| HOXB5 | homeobox B5 |
| HRASLS | HRAS-like suppressor |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IFT122 | intraflagellar transport 122 |
| IGFLR1 | IGF-like family receptor 1 |
| IGL | immunoglobulin lambda locus |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL6ST | interleukin 6 signal transducer |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KCNJ12 | potassium channel, inwardly rectifying subfamily J, member 12 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KIF5A | kinesin family member 5A |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| LEFTY1 | left-right determination factor 1 |
| LOC81691 | exonuclease NEF-sp |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MED18 | mediator complex subunit 18 |
| MED25 | mediator complex subunit 25 |
| METTL5 | methyltransferase like 5 |
| MON1B | MON1 secretory trafficking family member B |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NEB | nebulin |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| NUCB1 | nucleobindin 1 |
| PCDH1 | protocadherin 1 |
| PCNXL2 | pecanex-like 2 (Drosophila) |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PDLIM3 | PDZ and LIM domain 3 |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PHF20 | PHD finger protein 20 |
| PHLDB1 | pleckstrin homology-like domain, family B, member 1 |
| PLCL2 | phospholipase C-like 2 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLXNA1 | plexin A1 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRRC2B | proline-rich coiled-coil 2B |
| PTBP3 | polypyrimidine tract binding protein 3 |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RIN3 | Ras and Rab interactor 3 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| RYR2 | ryanodine receptor 2 (cardiac) |
| SAFB2 | scaffold attachment factor B2 |
| SCARB2 | scavenger receptor class B, member 2 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPN | sialophorin |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| SYNJ2 | synaptojanin 2 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TRAPPC6A | trafficking protein particle complex 6A |
| TUBGCP2 | tubulin, gamma complex associated protein 2 |
| UNKL | unkempt family zinc finger-like |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 |
| ZNF446 | zinc finger protein 446 |
| ZNF93 | zinc finger protein 93 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACTR3B | ARP3 actin-related protein 3 homolog B (yeast) |
| ADAMTSL3 | ADAMTS-like 3 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AFAP1 | actin filament associated protein 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ANOS1 | anosmin 1 |
| ARMC6 | armadillo repeat containing 6 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ATG14 | autophagy related 14 |
| ATP10D | ATPase, class V, type 10D |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| CAPG | capping protein (actin filament), gelsolin-like |
| CDC37L1 | cell division cycle 37-like 1 |
| CDH3 | cadherin 3, type 1, P-cadherin (placental) |
| CFAP44 | cilia and flagella associated protein 44 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| EGF | epidermal growth factor |
| EML4 | echinoderm microtubule associated protein like 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETNK2 | ethanolamine kinase 2 |
| FDXR | ferredoxin reductase |
| FER | fer (fps/fes related) tyrosine kinase |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 |
| GDE1 | glycerophosphodiester phosphodiesterase 1 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GRAMD1B | GRAM domain containing 1B |
| GTF2I | general transcription factor IIi |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HIST1H2BI | histone cluster 1, H2bi |
| HOMER2 | homer scaffolding protein 2 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| INO80D | INO80 complex subunit D |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0895 | KIAA0895 |
| KRT75 | keratin 75, type II |
| LINC00341 | long intergenic non-protein coding RNA 341 |
| LSR | lipolysis stimulated lipoprotein receptor |
| MOSPD3 | motile sperm domain containing 3 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MYO1D | myosin ID |
| NDRG4 | NDRG family member 4 |
| NHEJ1 | nonhomologous end-joining factor 1 |
| NID2 | nidogen 2 (osteonidogen) |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PEG3 | paternally expressed 3 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| POMT2 | protein-O-mannosyltransferase 2 |
| PSKH1 | protein serine kinase H1 |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAB4B | RAB4B, member RAS oncogene family |
| RANBP17 | RAN binding protein 17 |
| RFX7 | regulatory factor X, 7 |
| RNF141 | ring finger protein 141 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SNX15 | sorting nexin 15 |
| TEX2 | testis expressed 2 |
| TLN1 | talin 1 |
| TMEM120B | transmembrane protein 120B |
| TMEM177 | transmembrane protein 177 |
| TMEM8B | transmembrane protein 8B |
| TPCN1 | two pore segment channel 1 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRAIP | TRAF interacting protein |
| TTC17 | tetratricopeptide repeat domain 17 |
| TTC31 | tetratricopeptide repeat domain 31 |
| TTC33 | tetratricopeptide repeat domain 33 |
| UEVLD | UEV and lactate/malate dehyrogenase domains |
| USPL1 | ubiquitin specific peptidase like 1 |
| WDR91 | WD repeat domain 91 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZDHHC24 | zinc finger, DHHC-type containing 24 |
| ZNF571 | zinc finger protein 571 |
| ZNF668 | zinc finger protein 668 |
| ZNF747 | zinc finger protein 747 |
| ZXDC | ZXD family zinc finger C |