pindolol-1392 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the pindolol-1392 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACAA2 acetyl-CoA acyltransferase 2
ADORA3 adenosine A3 receptor
AKAP13 A kinase (PRKA) anchor protein 13
AKT3 v-akt murine thymoma viral oncogene homolog 3
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATG10 autophagy related 10
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
BCL7C B-cell CLL/lymphoma 7C
BTBD7 BTB (POZ) domain containing 7
C5ORF45 chromosome 5 open reading frame 45
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAPN10 calpain 10
CCHCR1 coiled-coil alpha-helical rod protein 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CST8 cystatin 8 (cystatin-related epididymal specific)
CTBP2 C-terminal binding protein 2
CYP2A7 cytochrome P450, family 2, subfamily A, polypeptide 7
DBR1 debranching RNA lariats 1
DGCR8 DGCR8 microprocessor complex subunit
DLK2 delta-like 2 homolog (Drosophila)
DUS2 dihydrouridine synthase 2
DXO decapping exoribonuclease
EIF5B eukaryotic translation initiation factor 5B
ENG endoglin
EPB41L2 erythrocyte membrane protein band 4.1-like 2
FANCF Fanconi anemia, complementation group F
FAS Fas cell surface death receptor
FCHO1 FCH domain only 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GLS glutaminase
GON4L gon-4-like (C. elegans)
GPR63 G protein-coupled receptor 63
GPRC5D G protein-coupled receptor, class C, group 5, member D
GSTM4 glutathione S-transferase mu 4
H2AFY H2A histone family, member Y
HNF1B HNF1 homeobox B
ICOSLG inducible T-cell co-stimulator ligand
KCTD5 potassium channel tetramerization domain containing 5
KIAA1109 KIAA1109
LARP4 La ribonucleoprotein domain family, member 4
LENEP lens epithelial protein
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LPAR1 lysophosphatidic acid receptor 1
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MORC3 MORC family CW-type zinc finger 3
MTMR3 myotubularin related protein 3
NFX1 nuclear transcription factor, X-box binding 1
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PFDN1 prefoldin subunit 1
PIDD1 p53-induced death domain protein 1
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PRRC1 proline-rich coiled-coil 1
PRRC2C proline-rich coiled-coil 2C
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTX3 pentraxin 3, long
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
QTRT1 queuine tRNA-ribosyltransferase 1
RAD17 RAD17 homolog (S. pombe)
RALB v-ral simian leukemia viral oncogene homolog B
RBM4B RNA binding motif protein 4B
RPL23AP32 ribosomal protein L23a pseudogene 32
SAP30 Sin3A-associated protein, 30kDa
SCYL3 SCY1-like 3 (S. cerevisiae)
SERBP1 SERPINE1 mRNA binding protein 1
SETD4 SET domain containing 4
SH3BP2 SH3-domain binding protein 2
SIAH1 siah E3 ubiquitin protein ligase 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLIT2 slit homolog 2 (Drosophila)
SMC5 structural maintenance of chromosomes 5
SS18 synovial sarcoma translocation, chromosome 18
STK19 serine/threonine kinase 19
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TASP1 taspase, threonine aspartase, 1
THTPA thiamine triphosphatase
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMSB4Y thymosin beta 4, Y-linked
TPSG1 tryptase gamma 1
TRAC T cell receptor alpha constant
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TSHB thyroid stimulating hormone, beta
TUBA4B tubulin, alpha 4b
TUBGCP3 tubulin, gamma complex associated protein 3
UBQLN4 ubiquilin 4
VASP vasodilator-stimulated phosphoprotein
WTAP Wilms tumor 1 associated protein
YIPF6 Yip1 domain family, member 6
ZEB2 zinc finger E-box binding homeobox 2
ZER1 zyg-11 related, cell cycle regulator
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF552 zinc finger protein 552

decreased expression

Symbol Name
ACVR2A activin A receptor, type IIA
AES amino-terminal enhancer of split
ARHGAP4 Rho GTPase activating protein 4
ATG4A autophagy related 4A, cysteine peptidase
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
C11ORF21 chromosome 11 open reading frame 21
CA7 carbonic anhydrase VII
CA9 carbonic anhydrase IX
CAPN1 calpain 1, (mu/I) large subunit
CD82 CD82 molecule
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLDN15 claudin 15
CLTCL1 clathrin, heavy chain-like 1
CORO7 coronin 7
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
DRAM1 DNA-damage regulated autophagy modulator 1
E4F1 E4F transcription factor 1
ELP6 elongator acetyltransferase complex subunit 6
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
FAM188A family with sequence similarity 188, member A
FAM53C family with sequence similarity 53, member C
FRS3 fibroblast growth factor receptor substrate 3
GALNS galactosamine (N-acetyl)-6-sulfatase
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11
GJD2 gap junction protein, delta 2, 36kDa
GPS1 G protein pathway suppressor 1
GSTA4 glutathione S-transferase alpha 4
GUSBP3 glucuronidase, beta pseudogene 3
HDAC5 histone deacetylase 5
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IDO1 indoleamine 2,3-dioxygenase 1
IGFLR1 IGF-like family receptor 1
IL2RB interleukin 2 receptor, beta
IMPAD1 inositol monophosphatase domain containing 1
KDELR1 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
KDM5C lysine (K)-specific demethylase 5C
KIF5A kinesin family member 5A
KIFAP3 kinesin-associated protein 3
KIFC1 kinesin family member C1
KPNA4 karyopherin alpha 4 (importin alpha 3)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
LZTR1 leucine-zipper-like transcription regulator 1
MAPK12 mitogen-activated protein kinase 12
MCAT malonyl CoA:ACP acyltransferase (mitochondrial)
MECR mitochondrial trans-2-enoyl-CoA reductase
MFSD12 major facilitator superfamily domain containing 12
MOB3B MOB kinase activator 3B
MOSPD3 motile sperm domain containing 3
MPV17 MpV17 mitochondrial inner membrane protein
MYO9A myosin IXA
NRBP1 nuclear receptor binding protein 1
NRGN neurogranin (protein kinase C substrate, RC3)
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9
OVGP1 oviductal glycoprotein 1, 120kDa
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PALM paralemmin
PCDHGB5 protocadherin gamma subfamily B, 5
PCOLCE2 procollagen C-endopeptidase enhancer 2
PHACTR4 phosphatase and actin regulator 4
PMM2 phosphomannomutase 2
PNPLA6 patatin-like phospholipase domain containing 6
PREB prolactin regulatory element binding
RASL11B RAS-like, family 11, member B
RBM47 RNA binding motif protein 47
REC8 REC8 meiotic recombination protein
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RPAP1 RNA polymerase II associated protein 1
S100A10 S100 calcium binding protein A10
SCAMP5 secretory carrier membrane protein 5
SCN1B sodium channel, voltage gated, type I beta subunit
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SESN1 sestrin 1
SETD1B SET domain containing 1B
SH3GL1 SH3-domain GRB2-like 1
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SNX6 sorting nexin 6
SPATA20 spermatogenesis associated 20
STRA13 stimulated by retinoic acid 13
TACC3 transforming, acidic coiled-coil containing protein 3
TEFM transcription elongation factor, mitochondrial
THEM6 thioesterase superfamily member 6
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TSPAN32 tetraspanin 32
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UEVLD UEV and lactate/malate dehyrogenase domains
UFSP2 UFM1-specific peptidase 2
USP20 ubiquitin specific peptidase 20
WWC2 WW and C2 domain containing 2
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YY2 YY2 transcription factor
ZBTB48 zinc finger and BTB domain containing 48
ZNF408 zinc finger protein 408
ZNF768 zinc finger protein 768
ZSCAN5A zinc finger and SCAN domain containing 5A