pindolol-2075 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the pindolol-2075 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANOS1 anosmin 1
ARHGAP6 Rho GTPase activating protein 6
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
BACE1 beta-site APP-cleaving enzyme 1
C19ORF60 chromosome 19 open reading frame 60
C19ORF66 chromosome 19 open reading frame 66
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCL20 chemokine (C-C motif) ligand 20
CLDN1 claudin 1
COBL cordon-bleu WH2 repeat protein
COL10A1 collagen, type X, alpha 1
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
DLG3 discs, large homolog 3 (Drosophila)
DMBT1 deleted in malignant brain tumors 1
DNASE2 deoxyribonuclease II, lysosomal
DOHH deoxyhypusine hydroxylase/monooxygenase
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FCMR Fc fragment of IgM receptor
FGFR1 fibroblast growth factor receptor 1
FOXA2 forkhead box A2
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GLG1 golgi glycoprotein 1
GNS glucosamine (N-acetyl)-6-sulfatase
GOLGA2 golgin A2
GPR137 G protein-coupled receptor 137
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HDGFRP3 hepatoma-derived growth factor, related protein 3
HMGN5 high mobility group nucleosome binding domain 5
HOOK1 hook microtubule-tethering protein 1
IL17RB interleukin 17 receptor B
IQSEC2 IQ motif and Sec7 domain 2
IRGQ immunity-related GTPase family, Q
ITPKB inositol-trisphosphate 3-kinase B
KAZN kazrin, periplakin interacting protein
KIAA0754 KIAA0754
LAT2 linker for activation of T cells family, member 2
LYPD3 LY6/PLAUR domain containing 3
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MBTD1 mbt domain containing 1
MIIP migration and invasion inhibitory protein
MTAP methylthioadenosine phosphorylase
MTERF4 mitochondrial transcription termination factor 4
MYOZ3 myozenin 3
MYRF myelin regulatory factor
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NMT2 N-myristoyltransferase 2
NNMT nicotinamide N-methyltransferase
NOP56 NOP56 ribonucleoprotein
NR4A2 nuclear receptor subfamily 4, group A, member 2
OAZ3 ornithine decarboxylase antizyme 3
PACS1 phosphofurin acidic cluster sorting protein 1
PCCA propionyl CoA carboxylase, alpha polypeptide
PGAP1 post-GPI attachment to proteins 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIDD1 p53-induced death domain protein 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PRR3 proline rich 3
PSD3 pleckstrin and Sec7 domain containing 3
PTK7 protein tyrosine kinase 7 (inactive)
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RHOBTB2 Rho-related BTB domain containing 2
SARS2 seryl-tRNA synthetase 2, mitochondrial
SLC38A7 solute carrier family 38, member 7
SLC46A3 solute carrier family 46, member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa
SUGP1 SURP and G patch domain containing 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
THBS3 thrombospondin 3
TLN2 talin 2
TMEM120B transmembrane protein 120B
TMEM242 transmembrane protein 242
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFSF15 tumor necrosis factor (ligand) superfamily, member 15
TP53I11 tumor protein p53 inducible protein 11
TRIM23 tripartite motif containing 23
TRIM29 tripartite motif containing 29
TSPAN9 tetraspanin 9
TTC38 tetratricopeptide repeat domain 38
USB1 U6 snRNA biogenesis 1
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBED4 zinc finger, BED-type containing 4
ZNF668 zinc finger protein 668
ZNRD1-AS1 ZNRD1 antisense RNA 1

decreased expression

Symbol Name
AHCTF1 AT hook containing transcription factor 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALPK1 alpha-kinase 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ASTE1 asteroid homolog 1 (Drosophila)
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG2B autophagy related 2B
C17ORF75 chromosome 17 open reading frame 75
C19ORF40 chromosome 19 open reading frame 40
C7ORF69 chromosome 7 open reading frame 69
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CBY1 chibby homolog 1 (Drosophila)
CDK3 cyclin-dependent kinase 3
DCLRE1B DNA cross-link repair 1B
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EGF epidermal growth factor
FAM155A family with sequence similarity 155, member A
FAM53B family with sequence similarity 53, member B
FBXL2 F-box and leucine-rich repeat protein 2
FLRT3 fibronectin leucine rich transmembrane protein 3
FMO4 flavin containing monooxygenase 4
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GDAP1 ganglioside induced differentiation associated protein 1
GID4 GID complex subunit 4
GPRASP1 G protein-coupled receptor associated sorting protein 1
GRWD1 glutamate-rich WD repeat containing 1
HIRA histone cell cycle regulator
HMHA1 histocompatibility (minor) HA-1
HOXB9 homeobox B9
HOXC10 homeobox C10
IFT54 intraflagellar transport 54
IFT81 intraflagellar transport 81
IGFLR1 IGF-like family receptor 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCTD15 potassium channel tetramerization domain containing 15
KIFC1 kinesin family member C1
KLHL36 kelch-like family member 36
L2HGDH L-2-hydroxyglutarate dehydrogenase
LINS lines homolog (Drosophila)
LMNB1 lamin B1
LOC730101 uncharacterized LOC730101
LPAR6 lysophosphatidic acid receptor 6
LRRC8E leucine rich repeat containing 8 family, member E
MAPK12 mitogen-activated protein kinase 12
MFGE8 milk fat globule-EGF factor 8 protein
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MIS18BP1 MIS18 binding protein 1
MX1 MX dynamin-like GTPase 1
NPDC1 neural proliferation, differentiation and control, 1
ODF2 outer dense fiber of sperm tails 2
PADI1 peptidyl arginine deiminase, type I
PARD6A par-6 family cell polarity regulator alpha
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PEX26 peroxisomal biogenesis factor 26
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLAC8 placenta-specific 8
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PRR14L proline rich 14-like
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAB20 RAB20, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RNF121 ring finger protein 121
RNF38 ring finger protein 38
SAMD9 sterile alpha motif domain containing 9
SCAI suppressor of cancer cell invasion
SCML2 sex comb on midleg-like 2 (Drosophila)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SIGLEC15 sialic acid binding Ig-like lectin 15
SIX1 SIX homeobox 1
SKI SKI proto-oncogene
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC35F6 solute carrier family 35, member F6
SNPH syntaphilin
SPEG SPEG complex locus
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SREK1IP1 SREK1-interacting protein 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYT17 synaptotagmin XVII
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBX19 T-box 19
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TKFC triokinase/FMN cyclase
TMOD3 tropomodulin 3 (ubiquitous)
TNRC6B trinucleotide repeat containing 6B
TPRA1 transmembrane protein, adipocyte asscociated 1
TRAIP TRAF interacting protein
TRDMT1 tRNA aspartic acid methyltransferase 1
TUBA3D tubulin, alpha 3d
UBTD1 ubiquitin domain containing 1
UNKL unkempt family zinc finger-like
USP19 ubiquitin specific peptidase 19
WDR33 WD repeat domain 33
ZMAT5 zinc finger, matrin-type 5
ZNF180 zinc finger protein 180
ZNF276 zinc finger protein 276
ZNF394 zinc finger protein 394
ZNF580 zinc finger protein 580