| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the pioglitazone-5925 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| AGER | advanced glycosylation end product-specific receptor |
| AKAP10 | A kinase (PRKA) anchor protein 10 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCNT2 | cyclin T2 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CLGN | calmegin |
| CNPY4 | canopy FGF signaling regulator 4 |
| CREB1 | cAMP responsive element binding protein 1 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DPF3 | D4, zinc and double PHD fingers, family 3 |
| DTNA | dystrobrevin, alpha |
| ELL | elongation factor RNA polymerase II |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| ENOX2 | ecto-NOX disulfide-thiol exchanger 2 |
| FBRS | fibrosin |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FGFR1 | fibroblast growth factor receptor 1 |
| FGFR4 | fibroblast growth factor receptor 4 |
| GALK1 | galactokinase 1 |
| GAP43 | growth associated protein 43 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GPATCH3 | G patch domain containing 3 |
| GPR137 | G protein-coupled receptor 137 |
| GPR157 | G protein-coupled receptor 157 |
| GSDMB | gasdermin B |
| GTF3C2 | general transcription factor IIIC, polypeptide 2, beta 110kDa |
| HIST1H2BJ | histone cluster 1, H2bj |
| IFNW1 | interferon, omega 1 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| INO80B | INO80 complex subunit B |
| KIF22 | kinesin family member 22 |
| KRT6B | keratin 6B, type II |
| KRT83 | keratin 83, type II |
| LIMCH1 | LIM and calponin homology domains 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| LRRC40 | leucine rich repeat containing 40 |
| MFAP3 | microfibrillar-associated protein 3 |
| MTA1 | metastasis associated 1 |
| N4BP1 | NEDD4 binding protein 1 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| OGFR | opioid growth factor receptor |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PLEC | plectin |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| RABIF | RAB interacting factor |
| RARA | retinoic acid receptor, alpha |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RPL35A | ribosomal protein L35a |
| RUSC2 | RUN and SH3 domain containing 2 |
| S100A8 | S100 calcium binding protein A8 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SECTM1 | secreted and transmembrane 1 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SND1-IT1 | SND1 intronic transcript 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRPR | signal recognition particle receptor (docking protein) |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TAPBP | TAP binding protein (tapasin) |
| TBX3 | T-box 3 |
| TCF25 | transcription factor 25 (basic helix-loop-helix) |
| TCF3 | transcription factor 3 |
| TET3 | tet methylcytosine dioxygenase 3 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TLR5 | toll-like receptor 5 |
| TMEM63A | transmembrane protein 63A |
| TMPRSS2 | transmembrane protease, serine 2 |
| TOR1AIP1 | torsin A interacting protein 1 |
| TPP1 | tripeptidyl peptidase I |
| TRIM2 | tripartite motif containing 2 |
| TSC2 | tuberous sclerosis 2 |
| TTC38 | tetratricopeptide repeat domain 38 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| UBTD1 | ubiquitin domain containing 1 |
| UPK3B | uroplakin 3B |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| WDR25 | WD repeat domain 25 |
| ZNF821 | zinc finger protein 821 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCB4 | ATP-binding cassette, sub-family B (MDR/TAP), member 4 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| AFF4 | AF4/FMR2 family, member 4 |
| AMPD1 | adenosine monophosphate deaminase 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARR3 | arrestin 3, retinal (X-arrestin) |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATF3 | activating transcription factor 3 |
| AVPR1B | arginine vasopressin receptor 1B |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| BIRC7 | baculoviral IAP repeat containing 7 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C1QB | complement component 1, q subcomponent, B chain |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CCNJL | cyclin J-like |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDON | cell adhesion associated, oncogene regulated |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CES3 | carboxylesterase 3 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CKMT2 | creatine kinase, mitochondrial 2 (sarcomeric) |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 |
| CNTN5 | contactin 5 |
| COL16A1 | collagen, type XVI, alpha 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| CYP4F8 | cytochrome P450, family 4, subfamily F, polypeptide 8 |
| DES | desmin |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| F11 | coagulation factor XI |
| FAAH | fatty acid amide hydrolase |
| FAM155A | family with sequence similarity 155, member A |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FGF4 | fibroblast growth factor 4 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HAMP | hepcidin antimicrobial peptide |
| HHAT | hedgehog acyltransferase |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HOXA4 | homeobox A4 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IRS4 | insulin receptor substrate 4 |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KIAA1456 | KIAA1456 |
| KLK5 | kallikrein-related peptidase 5 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LRRC20 | leucine rich repeat containing 20 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| METTL16 | methyltransferase like 16 |
| MORN1 | MORN repeat containing 1 |
| MSI1 | musashi RNA-binding protein 1 |
| MUC3B | mucin 3B, cell surface associated |
| OLFML2A | olfactomedin-like 2A |
| OR1D2 | olfactory receptor, family 1, subfamily D, member 2 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PDE9A | phosphodiesterase 9A |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| POLM | polymerase (DNA directed), mu |
| POMT2 | protein-O-mannosyltransferase 2 |
| POU4F2 | POU class 4 homeobox 2 |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRKCE | protein kinase C, epsilon |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RAB30 | RAB30, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| ROM1 | retinal outer segment membrane protein 1 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SREK1IP1 | SREK1-interacting protein 1 |
| TAS2R3 | taste receptor, type 2, member 3 |
| TEX40 | testis expressed 40 |
| TRAIP | TRAF interacting protein |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRIM21 | tripartite motif containing 21 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| UCN | urocortin |
| UNC119 | unc-119 homolog (C. elegans) |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZFHX4 | zinc finger homeobox 4 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF205 | zinc finger protein 205 |
| ZNF358 | zinc finger protein 358 |
| ZSCAN2 | zinc finger and SCAN domain containing 2 |
