| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the pioglitazone-5930 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABR | active BCR-related |
| ACACA | acetyl-CoA carboxylase alpha |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADM | adrenomedullin |
| AEN | apoptosis enhancing nuclease |
| AK5 | adenylate kinase 5 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ANGPTL4 | angiopoietin-like 4 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGAP22 | Rho GTPase activating protein 22 |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ASAP3 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 |
| ATP10A | ATPase, class V, type 10A |
| BTN3A2 | butyrophilin, subfamily 3, member A2 |
| CACYBP | calcyclin binding protein |
| CDH7 | cadherin 7, type 2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHKA | choline kinase alpha |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CIDEC | cell death-inducing DFFA-like effector c |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| DUSP2 | dual specificity phosphatase 2 |
| EDNRA | endothelin receptor type A |
| EFNB1 | ephrin-B1 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| EMP1 | epithelial membrane protein 1 |
| EPN1 | epsin 1 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FYB | FYN binding protein |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GK | glycerol kinase |
| HK2 | hexokinase 2 |
| HMOX1 | heme oxygenase 1 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL12A | interleukin 12A |
| IL17RB | interleukin 17 receptor B |
| IL1B | interleukin 1, beta |
| IRS2 | insulin receptor substrate 2 |
| ITGB5 | integrin, beta 5 |
| JUN | jun proto-oncogene |
| KCNJ12 | potassium channel, inwardly rectifying subfamily J, member 12 |
| KDM6B | lysine (K)-specific demethylase 6B |
| KIAA1467 | KIAA1467 |
| KLF4 | Kruppel-like factor 4 (gut) |
| LAMA4 | laminin, alpha 4 |
| LPIN1 | lipin 1 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAPT | microtubule-associated protein tau |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| MYO1B | myosin IB |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NOL10 | nucleolar protein 10 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
| NPY2R | neuropeptide Y receptor Y2 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OGFR | opioid growth factor receptor |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 |
| PFDN4 | prefoldin subunit 4 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PLCH1 | phospholipase C, eta 1 |
| PLIN2 | perilipin 2 |
| PML | promyelocytic leukemia |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H |
| PRKCD | protein kinase C, delta |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| RAB33B | RAB33B, member RAS oncogene family |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RBPMS | RNA binding protein with multiple splicing |
| RGS4 | regulator of G-protein signaling 4 |
| RHOB | ras homolog family member B |
| RPGRIP1L | RPGRIP1-like |
| RRP1 | ribosomal RNA processing 1 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| STK17B | serine/threonine kinase 17b |
| SUMO1 | small ubiquitin-like modifier 1 |
| SYMPK | symplekin |
| TLN2 | talin 2 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRIM29 | tripartite motif containing 29 |
| URI1 | URI1, prefoldin-like chaperone |
| ZNF267 | zinc finger protein 267 |
| ZNF710 | zinc finger protein 710 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AFF4 | AF4/FMR2 family, member 4 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ALS2CL | ALS2 C-terminal like |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ARSJ | arylsulfatase family, member J |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| AURKC | aurora kinase C |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1S | complement component 1, s subcomponent |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C8A | complement component 8, alpha polypeptide |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CD1C | CD1c molecule |
| CD70 | CD70 molecule |
| CHRDL1 | chordin-like 1 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| COL5A2 | collagen, type V, alpha 2 |
| CTGF | connective tissue growth factor |
| CTSO | cathepsin O |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| EXOSC1 | exosome component 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FBRS | fibrosin |
| FBXO2 | F-box protein 2 |
| FZD8 | frizzled class receptor 8 |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRM4 | glutamate receptor, metabotropic 4 |
| GRPR | gastrin-releasing peptide receptor |
| HDAC11 | histone deacetylase 11 |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST1H2AL | histone cluster 1, H2al |
| HIST1H2BC | histone cluster 1, H2bc |
| HOXB2 | homeobox B2 |
| IBSP | integrin-binding sialoprotein |
| IL33 | interleukin 33 |
| IQCC | IQ motif containing C |
| ISL1 | ISL LIM homeobox 1 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KRT4 | keratin 4, type II |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LPAR4 | lysophosphatidic acid receptor 4 |
| MAGIX | MAGI family member, X-linked |
| MANSC1 | MANSC domain containing 1 |
| MFI2 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| MIR622 | microRNA 622 |
| MMP13 | matrix metallopeptidase 13 |
| NABP1 | nucleic acid binding protein 1 |
| NCS1 | neuronal calcium sensor 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDP | Norrie disease (pseudoglioma) |
| NOL12 | nucleolar protein 12 |
| NRTN | neurturin |
| OLFML2A | olfactomedin-like 2A |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OSMR | oncostatin M receptor |
| PARD6A | par-6 family cell polarity regulator alpha |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PDGFRL | platelet-derived growth factor receptor-like |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PLAU | plasminogen activator, urokinase |
| PLD3 | phospholipase D family, member 3 |
| PLK2 | polo-like kinase 2 |
| POM121 | POM121 transmembrane nucleoporin |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRR14L | proline rich 14-like |
| PRR15L | proline rich 15-like |
| PRSS8 | protease, serine, 8 |
| RAB36 | RAB36, member RAS oncogene family |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC17A4 | solute carrier family 17, member 4 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 |
| TIMP4 | TIMP metallopeptidase inhibitor 4 |
| TMEM180 | transmembrane protein 180 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TRIB2 | tribbles pseudokinase 2 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TXK | TXK tyrosine kinase |
| WFDC2 | WAP four-disulfide core domain 2 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZNF253 | zinc finger protein 253 |
| ZNF749 | zinc finger protein 749 |
