| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the pioglitazone-5972 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AMT | aminomethyltransferase |
| ARL4C | ADP-ribosylation factor-like 4C |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BEGAIN | brain-enriched guanylate kinase-associated |
| C14ORF79 | chromosome 14 open reading frame 79 |
| CCDC186 | coiled-coil domain containing 186 |
| CCDC9 | coiled-coil domain containing 9 |
| CCNO | cyclin O |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CNN1 | calponin 1, basic, smooth muscle |
| COA1 | cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae) |
| COL6A1 | collagen, type VI, alpha 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDX52 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 |
| DICER1 | dicer 1, ribonuclease type III |
| DIXDC1 | DIX domain containing 1 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 |
| DTNA | dystrobrevin, alpha |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| EPOR | erythropoietin receptor |
| ERP44 | endoplasmic reticulum protein 44 |
| ETNK1 | ethanolamine kinase 1 |
| EXOC7 | exocyst complex component 7 |
| FBXL5 | F-box and leucine-rich repeat protein 5 |
| FBXO11 | F-box protein 11 |
| FGF2 | fibroblast growth factor 2 (basic) |
| FMO2 | flavin containing monooxygenase 2 (non-functional) |
| GAMT | guanidinoacetate N-methyltransferase |
| GPATCH2L | G patch domain containing 2-like |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) |
| GRB10 | growth factor receptor-bound protein 10 |
| HFE | hemochromatosis |
| HHAT | hedgehog acyltransferase |
| HIPK2 | homeodomain interacting protein kinase 2 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HSF4 | heat shock transcription factor 4 |
| HSPA12A | heat shock 70kDa protein 12A |
| HTATSF1 | HIV-1 Tat specific factor 1 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL1RAP | interleukin 1 receptor accessory protein |
| IL2RB | interleukin 2 receptor, beta |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KRT83 | keratin 83, type II |
| LIMCH1 | LIM and calponin homology domains 1 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRC14 | leucine rich repeat containing 14 |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MUC3B | mucin 3B, cell surface associated |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NMT2 | N-myristoyltransferase 2 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OCLM | oculomedin |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase |
| PARVA | parvin, alpha |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PITX1 | paired-like homeodomain 1 |
| PPP2R2B | protein phosphatase 2, regulatory subunit B, beta |
| PVR | poliovirus receptor |
| RAB27B | RAB27B, member RAS oncogene family |
| RANBP3 | RAN binding protein 3 |
| RGS10 | regulator of G-protein signaling 10 |
| RGS12 | regulator of G-protein signaling 12 |
| RGS14 | regulator of G-protein signaling 14 |
| RIN3 | Ras and Rab interactor 3 |
| ROM1 | retinal outer segment membrane protein 1 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SH3BP2 | SH3-domain binding protein 2 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SIRT3 | sirtuin 3 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SLPI | secretory leukocyte peptidase inhibitor |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SMC1A | structural maintenance of chromosomes 1A |
| TAZ | tafazzin |
| TCF25 | transcription factor 25 (basic helix-loop-helix) |
| TDRD12 | tudor domain containing 12 |
| TPMT | thiopurine S-methyltransferase |
| TRIM5 | tripartite motif containing 5 |
| USP12 | ubiquitin specific peptidase 12 |
| VASH2 | vasohibin 2 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZNF304 | zinc finger protein 304 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF586 | zinc finger protein 586 |
| Symbol | Name |
|---|---|
| AIM2 | absent in melanoma 2 |
| ALDOAP2 | aldolase A, fructose-bisphosphate pseudogene 2 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP2A1 | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
| BAG4 | BCL2-associated athanogene 4 |
| BDKRB2 | bradykinin receptor B2 |
| BDNF | brain-derived neurotrophic factor |
| BICC1 | BicC family RNA binding protein 1 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| CACNG3 | calcium channel, voltage-dependent, gamma subunit 3 |
| CBX8 | chromobox homolog 8 |
| CCDC134 | coiled-coil domain containing 134 |
| CCDC7 | coiled-coil domain containing 7 |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CD83 | CD83 molecule |
| CLSPN | claspin |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNTN5 | contactin 5 |
| CPNE7 | copine VII |
| CST4 | cystatin S |
| CTRL | chymotrypsin-like |
| DSPP | dentin sialophosphoprotein |
| EGFL7 | EGF-like-domain, multiple 7 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| EMCN | endomucin |
| EREG | epiregulin |
| EXD3 | exonuclease 3'-5' domain containing 3 |
| FIGF | c-fos induced growth factor (vascular endothelial growth factor D) |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GAS2 | growth arrest-specific 2 |
| GAST | gastrin |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GFAP | glial fibrillary acidic protein |
| GGTLC1 | gamma-glutamyltransferase light chain 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GRIP2 | glutamate receptor interacting protein 2 |
| HAMP | hepcidin antimicrobial peptide |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HPR | haptoglobin-related protein |
| HSF2BP | heat shock transcription factor 2 binding protein |
| ITM2C | integral membrane protein 2C |
| KIAA1456 | KIAA1456 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LHX3 | LIM homeobox 3 |
| LINS | lines homolog (Drosophila) |
| LOC729164 | hCG1732469 |
| LRP4 | low density lipoprotein receptor-related protein 4 |
| LRRTM2 | leucine rich repeat transmembrane neuronal 2 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PCBP3 | poly(rC) binding protein 3 |
| PCDHA5 | protocadherin alpha 5 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| POM121 | POM121 transmembrane nucleoporin |
| POU3F2 | POU class 3 homeobox 2 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRKACG | protein kinase, cAMP-dependent, catalytic, gamma |
| PRMT8 | protein arginine methyltransferase 8 |
| PRR4 | proline rich 4 (lacrimal) |
| RAB3A | RAB3A, member RAS oncogene family |
| RNF125 | ring finger protein 125, E3 ubiquitin protein ligase |
| RORC | RAR-related orphan receptor C |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SHARPIN | SHANK-associated RH domain interactor |
| SIX1 | SIX homeobox 1 |
| SLC18A3 | solute carrier family 18 (vesicular acetylcholine transporter), member 3 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SLC9A3R2 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SOCS7 | suppressor of cytokine signaling 7 |
| TMEM104 | transmembrane protein 104 |
| TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 |
| TNFRSF8 | tumor necrosis factor receptor superfamily, member 8 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TSPAN2 | tetraspanin 2 |
| UNC13A | unc-13 homolog A (C. elegans) |
| VGF | VGF nerve growth factor inducible |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF423 | zinc finger protein 423 |
| ZNF639 | zinc finger protein 639 |
| ZNF76 | zinc finger protein 76 |
