| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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194 genes differentially expressed following the pioglitazone-5977 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AIF1 | allograft inflammatory factor 1 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| ANGPTL4 | angiopoietin-like 4 |
| ANKRD55 | ankyrin repeat domain 55 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ATP10A | ATPase, class V, type 10A |
| BTBD18 | BTB (POZ) domain containing 18 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| C14ORF1 | chromosome 14 open reading frame 1 |
| CDH7 | cadherin 7, type 2 |
| CDK18 | cyclin-dependent kinase 18 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLCN1 | chloride channel, voltage-sensitive 1 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) |
| CWH43 | cell wall biogenesis 43 C-terminal homolog (S. cerevisiae) |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| EFNA3 | ephrin-A3 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EMC3 | ER membrane protein complex subunit 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP5 | FK506 binding protein 5 |
| FRMD1 | FERM domain containing 1 |
| GAL | galanin/GMAP prepropeptide |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| HBQ1 | hemoglobin, theta 1 |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HIC2 | hypermethylated in cancer 2 |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| IFFO1 | intermediate filament family orphan 1 |
| IL11 | interleukin 11 |
| IL17RA | interleukin 17 receptor A |
| IL1B | interleukin 1, beta |
| IQCK | IQ motif containing K |
| JUN | jun proto-oncogene |
| KIR2DL1 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 |
| KIRREL | kin of IRRE like (Drosophila) |
| KLF2 | Kruppel-like factor 2 |
| KRT31 | keratin 31, type I |
| LPIN1 | lipin 1 |
| LRRN2 | leucine rich repeat neuronal 2 |
| LUZP4 | leucine zipper protein 4 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MECP2 | methyl CpG binding protein 2 |
| MFN2 | mitofusin 2 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRP2 | neuropilin 2 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PDE10A | phosphodiesterase 10A |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PDZK1 | PDZ domain containing 1 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PLIN2 | perilipin 2 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PRKCD | protein kinase C, delta |
| PRKCE | protein kinase C, epsilon |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RHOT2 | ras homolog family member T2 |
| RIN3 | Ras and Rab interactor 3 |
| RPL10 | ribosomal protein L10 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SQSTM1 | sequestosome 1 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| TAT | tyrosine aminotransferase |
| TFEB | transcription factor EB |
| TK2 | thymidine kinase 2, mitochondrial |
| TMEM209 | transmembrane protein 209 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TRIM29 | tripartite motif containing 29 |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF749 | zinc finger protein 749 |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ALPK3 | alpha-kinase 3 |
| AOC2 | amine oxidase, copper containing 2 (retina-specific) |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| BMP4 | bone morphogenetic protein 4 |
| C1RL | complement component 1, r subcomponent-like |
| C22ORF46 | chromosome 22 open reading frame 46 |
| C5ORF42 | chromosome 5 open reading frame 42 |
| CARF | calcium responsive transcription factor |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CERS4 | ceramide synthase 4 |
| CHM | choroideremia (Rab escort protein 1) |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CTGF | connective tissue growth factor |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DSCAM | Down syndrome cell adhesion molecule |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERCC2 | excision repair cross-complementation group 2 |
| EVI2B | ecotropic viral integration site 2B |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM186A | family with sequence similarity 186, member A |
| FBXO31 | F-box protein 31 |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FMO4 | flavin containing monooxygenase 4 |
| GAN | gigaxonin |
| GAS8 | growth arrest-specific 8 |
| GDAP2 | ganglioside induced differentiation associated protein 2 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPR37 | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H4C | histone cluster 1, H4c |
| HMHA1 | histocompatibility (minor) HA-1 |
| HOXA2 | homeobox A2 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IGFBP1 | insulin-like growth factor binding protein 1 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KLF15 | Kruppel-like factor 15 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LOC730101 | uncharacterized LOC730101 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MLLT4-AS1 | MLLT4 antisense RNA 1 (head to head) |
| MMP13 | matrix metallopeptidase 13 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NEK11 | NIMA-related kinase 11 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OSMR | oncostatin M receptor |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PADI2 | peptidyl arginine deiminase, type II |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PLK2 | polo-like kinase 2 |
| POLL | polymerase (DNA directed), lambda |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RGS17 | regulator of G-protein signaling 17 |
| RWDD2A | RWD domain containing 2A |
| SCEL | sciellin |
| SEPP1 | selenoprotein P, plasma, 1 |
| SHPK | sedoheptulokinase |
| SHROOM2 | shroom family member 2 |
| SIX1 | SIX homeobox 1 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SOSTDC1 | sclerostin domain containing 1 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSBP3 | single stranded DNA binding protein 3 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SYNGR3 | synaptogyrin 3 |
| TAS2R1 | taste receptor, type 2, member 1 |
| TGFB3 | transforming growth factor, beta 3 |
| TH | tyrosine hydroxylase |
| TMEM104 | transmembrane protein 104 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TUBA3C | tubulin, alpha 3c |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VN1R1 | vomeronasal 1 receptor 1 |
| VNN2 | vanin 2 |
| WDR62 | WD repeat domain 62 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZFPM2 | zinc finger protein, FOG family member 2 |
| ZNF230 | zinc finger protein 230 |
| ZNF286A | zinc finger protein 286A |
| ZNF446 | zinc finger protein 446 |
