| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the pioglitazone-7088 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ABHD6 | abhydrolase domain containing 6 |
| ADCY1 | adenylate cyclase 1 (brain) |
| ADM | adrenomedullin |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ANAPC5 | anaphase promoting complex subunit 5 |
| ANGPTL4 | angiopoietin-like 4 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ATP10A | ATPase, class V, type 10A |
| ATP13A3 | ATPase type 13A3 |
| BAG1 | BCL2-associated athanogene |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CDH7 | cadherin 7, type 2 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| COBL | cordon-bleu WH2 repeat protein |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DUSP1 | dual specificity phosphatase 1 |
| EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| EN1 | engrailed homeobox 1 |
| EN2 | engrailed homeobox 2 |
| EPOR | erythropoietin receptor |
| FA2H | fatty acid 2-hydroxylase |
| FABP4 | fatty acid binding protein 4, adipocyte |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| HBEGF | heparin-binding EGF-like growth factor |
| HK2 | hexokinase 2 |
| HMOX1 | heme oxygenase 1 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| HTT | huntingtin |
| IFI44L | interferon-induced protein 44-like |
| IL11 | interleukin 11 |
| IL1B | interleukin 1, beta |
| JUN | jun proto-oncogene |
| KLF11 | Kruppel-like factor 11 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLF5 | Kruppel-like factor 5 (intestinal) |
| LAMA4 | laminin, alpha 4 |
| LPIN1 | lipin 1 |
| MAL | mal, T-cell differentiation protein |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 |
| MBTD1 | mbt domain containing 1 |
| METTL1 | methyltransferase like 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NRSN2 | neurensin 2 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLIN2 | perilipin 2 |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PRKCD | protein kinase C, delta |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTGES | prostaglandin E synthase |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RBPMS | RNA binding protein with multiple splicing |
| RGS19 | regulator of G-protein signaling 19 |
| RGS4 | regulator of G-protein signaling 4 |
| RHOB | ras homolog family member B |
| RRN3 | RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) |
| RRP7A | ribosomal RNA processing 7 homolog A (S. cerevisiae) |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit |
| SDC2 | syndecan 2 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A |
| SFN | stratifin |
| SFT2D2 | SFT2 domain containing 2 |
| SH2D2A | SH2 domain containing 2A |
| SIK1 | salt-inducible kinase 1 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC19A1 | solute carrier family 19 (folate transporter), member 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SMARCA5 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 |
| SMIM8 | small integral membrane protein 8 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SORBS1 | sorbin and SH3 domain containing 1 |
| STOM | stomatin |
| TCF3 | transcription factor 3 |
| THBD | thrombomodulin |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TRIM29 | tripartite motif containing 29 |
| TSPAN12 | tetraspanin 12 |
| TUBA3C | tubulin, alpha 3c |
| ZNF426 | zinc finger protein 426 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| APH1A | APH1A gamma secretase subunit |
| APH1B | APH1B gamma secretase subunit |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| BAX | BCL2-associated X protein |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BDNF | brain-derived neurotrophic factor |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| BOLA1 | bolA family member 1 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CBS | cystathionine-beta-synthase |
| CCNO | cyclin O |
| COL5A2 | collagen, type V, alpha 2 |
| CTGF | connective tissue growth factor |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DCLRE1A | DNA cross-link repair 1A |
| DPM2 | dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| EAF2 | ELL associated factor 2 |
| EFNA4 | ephrin-A4 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXO2 | F-box protein 2 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GATA3 | GATA binding protein 3 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GOLGA1 | golgin A1 |
| GPRASP1 | G protein-coupled receptor associated sorting protein 1 |
| GRPR | gastrin-releasing peptide receptor |
| H1F0 | H1 histone family, member 0 |
| HIRA | histone cell cycle regulator |
| HIST1H2BI | histone cluster 1, H2bi |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| IL33 | interleukin 33 |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KIF14 | kinesin family member 14 |
| KIFC1 | kinesin family member C1 |
| KLHL12 | kelch-like family member 12 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMNB1 | lamin B1 |
| MCMBP | minichromosome maintenance complex binding protein |
| MRPL28 | mitochondrial ribosomal protein L28 |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NR3C2 | nuclear receptor subfamily 3, group C, member 2 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLAT | plasminogen activator, tissue |
| PLAU | plasminogen activator, urokinase |
| PLK2 | polo-like kinase 2 |
| PLXNB3 | plexin B3 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PRR15L | proline rich 15-like |
| PRSS22 | protease, serine, 22 |
| PSENEN | presenilin enhancer gamma secretase subunit |
| PTGFR | prostaglandin F receptor (FP) |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RGS2 | regulator of G-protein signaling 2 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SCEL | sciellin |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SMA4 | glucuronidase, beta pseudogene |
| SPANXC | SPANX family, member C |
| SPIN1 | spindlin 1 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| STK16 | serine/threonine kinase 16 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TCTN2 | tectonic family member 2 |
| TMEM187 | transmembrane protein 187 |
| TMEM209 | transmembrane protein 209 |
| TRIM45 | tripartite motif containing 45 |
| TSPAN15 | tetraspanin 15 |
| TUBA3D | tubulin, alpha 3d |
| YAP1 | Yes-associated protein 1 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF248 | zinc finger protein 248 |
| ZNF606 | zinc finger protein 606 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF816 | zinc finger protein 816 |
