| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the pioglitazone-7528 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD6 | abhydrolase domain containing 6 |
| ADCY1 | adenylate cyclase 1 (brain) |
| ADM | adrenomedullin |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ANGPTL4 | angiopoietin-like 4 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGAP26 | Rho GTPase activating protein 26 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CACTIN | cactin, spliceosome C complex subunit |
| CCNA1 | cyclin A1 |
| CCPG1 | cell cycle progression 1 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CIB2 | calcium and integrin binding family member 2 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| DGCR2 | DiGeorge syndrome critical region gene 2 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DMBT1 | deleted in malignant brain tumors 1 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DVL3 | dishevelled segment polarity protein 3 |
| EIF1 | eukaryotic translation initiation factor 1 |
| EIF3M | eukaryotic translation initiation factor 3, subunit M |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EMP1 | epithelial membrane protein 1 |
| EN2 | engrailed homeobox 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FA2H | fatty acid 2-hydroxylase |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FH | fumarate hydratase |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPALPP1 | GPALPP motifs containing 1 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 |
| IFI44L | interferon-induced protein 44-like |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| IL15RA | interleukin 15 receptor, alpha |
| IL1B | interleukin 1, beta |
| JAG2 | jagged 2 |
| JUN | jun proto-oncogene |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KRT6A | keratin 6A, type II |
| LAMA4 | laminin, alpha 4 |
| LINC00260 | long intergenic non-protein coding RNA 260 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| LPIN1 | lipin 1 |
| LRRN2 | leucine rich repeat neuronal 2 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAL | mal, T-cell differentiation protein |
| MINK1 | misshapen-like kinase 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MTAP | methylthioadenosine phosphorylase |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NSUN6 | NOP2/Sun domain family, member 6 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PCDH1 | protocadherin 1 |
| PDLIM4 | PDZ and LIM domain 4 |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PLIN2 | perilipin 2 |
| PRKCD | protein kinase C, delta |
| PTGES | prostaglandin E synthase |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RAB11B | RAB11B, member RAS oncogene family |
| RGS4 | regulator of G-protein signaling 4 |
| RHOB | ras homolog family member B |
| RPL35A | ribosomal protein L35a |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit |
| SDC2 | syndecan 2 |
| SIK1 | salt-inducible kinase 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| STK10 | serine/threonine kinase 10 |
| TBC1D30 | TBC1 domain family, member 30 |
| TFF2 | trefoil factor 2 |
| THBS3 | thrombospondin 3 |
| TMEM47 | transmembrane protein 47 |
| TSC22D4 | TSC22 domain family, member 4 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| WAS | Wiskott-Aldrich syndrome |
| WT1 | Wilms tumor 1 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ADGRG6 | adhesion G protein-coupled receptor G6 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| APOL6 | apolipoprotein L, 6 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ARID5B | AT rich interactive domain 5B (MRF1-like) |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| BDNF | brain-derived neurotrophic factor |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCDC186 | coiled-coil domain containing 186 |
| CD82 | CD82 molecule |
| COL5A2 | collagen, type V, alpha 2 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CRYGC | crystallin, gamma C |
| CRYL1 | crystallin, lambda 1 |
| CRYZ | crystallin, zeta (quinone reductase) |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CTAGE9 | CTAGE family, member 9 |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTGF | connective tissue growth factor |
| CTSO | cathepsin O |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| EAF2 | ELL associated factor 2 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FER | fer (fps/fes related) tyrosine kinase |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| FZD8 | frizzled class receptor 8 |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GPATCH2 | G patch domain containing 2 |
| GRPR | gastrin-releasing peptide receptor |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2I | general transcription factor IIi |
| H1F0 | H1 histone family, member 0 |
| HCG4 | HLA complex group 4 (non-protein coding) |
| HDAC7 | histone deacetylase 7 |
| HERC2P3 | hect domain and RLD 2 pseudogene 3 |
| HIST1H2BC | histone cluster 1, H2bc |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT81 | intraflagellar transport 81 |
| IL18 | interleukin 18 |
| IL33 | interleukin 33 |
| IRF2 | interferon regulatory factor 2 |
| KIAA0319L | KIAA0319-like |
| KIAA1462 | KIAA1462 |
| LMNB1 | lamin B1 |
| LOC730101 | uncharacterized LOC730101 |
| LRRC49 | leucine rich repeat containing 49 |
| LRRC61 | leucine rich repeat containing 61 |
| MCTP1 | multiple C2 domains, transmembrane 1 |
| MRAS | muscle RAS oncogene homolog |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NME5 | NME/NM23 family member 5 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRAS | neuroblastoma RAS viral (v-ras) oncogene homolog |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OCLN | occludin |
| ORC1 | origin recognition complex, subunit 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PLAU | plasminogen activator, urokinase |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PLK2 | polo-like kinase 2 |
| PPARG | peroxisome proliferator-activated receptor gamma |
| RAB23 | RAB23, member RAS oncogene family |
| RCAN3 | RCAN family member 3 |
| RNF43 | ring finger protein 43 |
| RPS17P5 | ribosomal protein S17 pseudogene 5 |
| SERPINB7 | serpin peptidase inhibitor, clade B (ovalbumin), member 7 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SHROOM2 | shroom family member 2 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| ZFHX2 | zinc finger homeobox 2 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF227 | zinc finger protein 227 |
| ZNF573 | zinc finger protein 573 |
| ZNF675 | zinc finger protein 675 |
| ZNF8 | zinc finger protein 8 |
