pioglitazone Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic activity. (Chemical Entities of Biological Interest Ontology, CHEBI_8228)
Similar Terms
Downloads & Tools

Genes

22 genes co-occuring with the biological term pioglitazone in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
AGER advanced glycosylation end product-specific receptor
CCND1 cyclin D1
CD36 CD36 molecule (thrombospondin receptor)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CISD1 CDGSH iron sulfur domain 1
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
EDN1 endothelin 1
GYS1 glycogen synthase 1 (muscle)
IGFBP3 insulin-like growth factor binding protein 3
JUN jun proto-oncogene
LANCL2 LanC lantibiotic synthetase component C-like 2 (bacterial)
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PTPRD protein tyrosine phosphatase, receptor type, D
RBP4 retinol binding protein 4, plasma
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
TERT telomerase reverse transcriptase
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TP53 tumor protein p53