piperacetazine-3574 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the piperacetazine-3574 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABI2 abl-interactor 2
ACAA2 acetyl-CoA acyltransferase 2
ADGRE1 adhesion G protein-coupled receptor E1
AGFG2 ArfGAP with FG repeats 2
AKAP4 A kinase (PRKA) anchor protein 4
AKAP9 A kinase (PRKA) anchor protein 9
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BLNK B-cell linker
C2ORF27A chromosome 2 open reading frame 27A
C8ORF44 chromosome 8 open reading frame 44
CALCR calcitonin receptor
CALML3 calmodulin-like 3
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC85B coiled-coil domain containing 85B
CDK13 cyclin-dependent kinase 13
CELF2 CUGBP, Elav-like family member 2
CFHR4 complement factor H-related 4
CNOT4 CCR4-NOT transcription complex, subunit 4
COL9A3 collagen, type IX, alpha 3
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPEB3 cytoplasmic polyadenylation element binding protein 3
DAPK2 death-associated protein kinase 2
DIXDC1 DIX domain containing 1
DOCK5 dedicator of cytokinesis 5
EFNA3 ephrin-A3
EFS embryonal Fyn-associated substrate
EHD2 EH-domain containing 2
ELAC2 elaC ribonuclease Z 2
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ETV5 ets variant 5
FAM65B family with sequence similarity 65, member B
FLCN folliculin
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GOLGA2P5 golgin A2 pseudogene 5
GTDC1 glycosyltransferase-like domain containing 1
GUSBP3 glucuronidase, beta pseudogene 3
HIP1 huntingtin interacting protein 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
ICOSLG inducible T-cell co-stimulator ligand
INADL InaD-like (Drosophila)
INSIG1 insulin induced gene 1
IQSEC2 IQ motif and Sec7 domain 2
KIAA1109 KIAA1109
KLF9 Kruppel-like factor 9
KLHDC8A kelch domain containing 8A
LMF2 lipase maturation factor 2
LPIN1 lipin 1
LTBP4 latent transforming growth factor beta binding protein 4
LYST lysosomal trafficking regulator
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MGAM maltase-glucoamylase
MMP13 matrix metallopeptidase 13
MUC3B mucin 3B, cell surface associated
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NF1 neurofibromin 1
NPC1 Niemann-Pick disease, type C1
PHF20L1 PHD finger protein 20-like 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLK4 polo-like kinase 4
POFUT1 protein O-fucosyltransferase 1
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PROL1 proline rich, lacrimal 1
QKI QKI, KH domain containing, RNA binding
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS6 regulator of G-protein signaling 6
RHBDD3 rhomboid domain containing 3
RNF6 ring finger protein (C3H2C3 type) 6
RSU1 Ras suppressor protein 1
RUFY3 RUN and FYVE domain containing 3
SCN11A sodium channel, voltage gated, type XI alpha subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SIRT5 sirtuin 5
SLAMF7 SLAM family member 7
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNCG synuclein, gamma (breast cancer-specific protein 1)
STXBP5L syntaxin binding protein 5-like
TBX2 T-box 2
TEP1 telomerase-associated protein 1
TM4SF1 transmembrane 4 L six family member 1
TMEM63A transmembrane protein 63A
TMEM8B transmembrane protein 8B
TMPRSS2 transmembrane protease, serine 2
TMPRSS4 transmembrane protease, serine 4
TOR1AIP1 torsin A interacting protein 1
TP63 tumor protein p63
TRIM36 tripartite motif containing 36
UBQLN4 ubiquilin 4
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WDTC1 WD and tetratricopeptide repeats 1
WSCD1 WSC domain containing 1
ZMAT4 zinc finger, matrin-type 4
ZMYND8 zinc finger, MYND-type containing 8
ZNF165 zinc finger protein 165
ZNF506 zinc finger protein 506
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABHD17B abhydrolase domain containing 17B
ACAD10 acyl-CoA dehydrogenase family, member 10
ACTL8 actin-like 8
ALPK1 alpha-kinase 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BFSP1 beaded filament structural protein 1, filensin
BRPF1 bromodomain and PHD finger containing, 1
C14ORF93 chromosome 14 open reading frame 93
C1ORF159 chromosome 1 open reading frame 159
C7ORF43 chromosome 7 open reading frame 43
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMTA2 calmodulin binding transcription activator 2
CCDC88C coiled-coil domain containing 88C
CCND3 cyclin D3
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CENPO centromere protein O
CFD complement factor D (adipsin)
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CRY2 cryptochrome circadian clock 2
CSTA cystatin A (stefin A)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DSCAM Down syndrome cell adhesion molecule
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EMID1 EMI domain containing 1
ERN1 endoplasmic reticulum to nucleus signaling 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EXD3 exonuclease 3'-5' domain containing 3
FOSL1 FOS-like antigen 1
FOXN2 forkhead box N2
GFPT2 glutamine-fructose-6-phosphate transaminase 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNL1 guanine nucleotide binding protein-like 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
JUNB jun B proto-oncogene
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0319L KIAA0319-like
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LIN7A lin-7 homolog A (C. elegans)
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAST3 microtubule associated serine/threonine kinase 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MED15 mediator complex subunit 15
MFAP2 microfibrillar-associated protein 2
MTSS1L metastasis suppressor 1-like
NEK11 NIMA-related kinase 11
NPM3 nucleophosmin/nucleoplasmin 3
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PADI1 peptidyl arginine deiminase, type I
PDE12 phosphodiesterase 12
PNPLA6 patatin-like phospholipase domain containing 6
POPDC3 popeye domain containing 3
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PRB3 proline-rich protein BstNI subfamily 3
PTCD2 pentatricopeptide repeat domain 2
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3A RAB3A, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABL6 RAB, member RAS oncogene family-like 6
RNF126P1 ring finger protein 126 pseudogene 1
RNF39 ring finger protein 39
RNF43 ring finger protein 43
SCUBE3 signal peptide, CUB domain, EGF-like 3
SECTM1 secreted and transmembrane 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SHARPIN SHANK-associated RH domain interactor
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
STIM1 stromal interaction molecule 1
SULT4A1 sulfotransferase family 4A, member 1
SUSD4 sushi domain containing 4
TGFBR3 transforming growth factor, beta receptor III
TMEM121 transmembrane protein 121
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TUBA3C tubulin, alpha 3c
UNC119 unc-119 homolog (C. elegans)
USP21 ubiquitin specific peptidase 21
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
XAB2 XPA binding protein 2
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZMAT5 zinc finger, matrin-type 5
ZNF16 zinc finger protein 16
ZNF747 zinc finger protein 747