piperacetazine-5834 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the piperacetazine-5834 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
AIM2 absent in melanoma 2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
AMPD3 adenosine monophosphate deaminase 3
AP4E1 adaptor-related protein complex 4, epsilon 1 subunit
APOLD1 apolipoprotein L domain containing 1
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASIC1 acid sensing (proton gated) ion channel 1
ASPHD1 aspartate beta-hydroxylase domain containing 1
B9D1 B9 protein domain 1
BEX4 brain expressed, X-linked 4
BMP2K BMP2 inducible kinase
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BTC betacellulin
CADM4 cell adhesion molecule 4
CDX1 caudal type homeobox 1
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CNOT8 CCR4-NOT transcription complex, subunit 8
CRYGD crystallin, gamma D
CTNS cystinosin, lysosomal cystine transporter
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DAAM2 dishevelled associated activator of morphogenesis 2
DCAKD dephospho-CoA kinase domain containing
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DENND3 DENN/MADD domain containing 3
DGCR6L DiGeorge syndrome critical region gene 6-like
DLC1 DLC1 Rho GTPase activating protein
DZIP1 DAZ interacting zinc finger protein 1
E2F4 E2F transcription factor 4, p107/p130-binding
EFR3B EFR3 homolog B (S. cerevisiae)
ELSPBP1 epididymal sperm binding protein 1
ETV1 ets variant 1
FGFBP1 fibroblast growth factor binding protein 1
FNDC3A fibronectin type III domain containing 3A
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GPM6A glycoprotein M6A
HIST1H3C histone cluster 1, H3c
HOOK1 hook microtubule-tethering protein 1
HOXA4 homeobox A4
IFNA14 interferon, alpha 14
IGHM immunoglobulin heavy constant mu
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INSIG1 insulin induced gene 1
ISG20 interferon stimulated exonuclease gene 20kDa
JUND jun D proto-oncogene
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KLF13 Kruppel-like factor 13
KLF6 Kruppel-like factor 6
LAMB4 laminin, beta 4
LOC647070 uncharacterized LOC647070
LYPD3 LY6/PLAUR domain containing 3
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MTERF4 mitochondrial transcription termination factor 4
MVK mevalonate kinase
NDRG1 N-myc downstream regulated 1
NEK11 NIMA-related kinase 11
NF1 neurofibromin 1
NOP14-AS1 NOP14 antisense RNA 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
OAZ3 ornithine decarboxylase antizyme 3
PDGFB platelet-derived growth factor beta polypeptide
PELO pelota homolog (Drosophila)
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PLAC4 placenta-specific 4
POU2F3 POU class 2 homeobox 3
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PROL1 proline rich, lacrimal 1
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBMS2 RNA binding motif, single stranded interacting protein 2
REPS2 RALBP1 associated Eps domain containing 2
RIBC2 RIB43A domain with coiled-coils 2
RPL10 ribosomal protein L10
SCN10A sodium channel, voltage gated, type X alpha subunit
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SIRPB1 signal-regulatory protein beta 1
SIX3 SIX homeobox 3
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SQLE squalene epoxidase
STARD3 StAR-related lipid transfer (START) domain containing 3
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
SYK spleen tyrosine kinase
THOC5 THO complex 5
TINAGL1 tubulointerstitial nephritis antigen-like 1
TLDC1 TBC/LysM-associated domain containing 1
TMEM144 transmembrane protein 144
TSHR thyroid stimulating hormone receptor
TSKU tsukushi, small leucine rich proteoglycan
UNC119 unc-119 homolog (C. elegans)
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF224 zinc finger protein 224
ZNF571 zinc finger protein 571
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide
BDNF brain-derived neurotrophic factor
BTF3P12 basic transcription factor 3 pseudogene 12
C11ORF63 chromosome 11 open reading frame 63
C11ORF73 chromosome 11 open reading frame 73
C17ORF75 chromosome 17 open reading frame 75
C1ORF159 chromosome 1 open reading frame 159
C7ORF43 chromosome 7 open reading frame 43
CCNA1 cyclin A1
CDADC1 cytidine and dCMP deaminase domain containing 1
CLEC16A C-type lectin domain family 16, member A
COCH cochlin
COQ4 coenzyme Q4
CPEB1 cytoplasmic polyadenylation element binding protein 1
CTDNEP1 CTD nuclear envelope phosphatase 1
CTPS2 CTP synthase 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL3 chemokine (C-X-C motif) ligand 3
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DCAF17 DDB1 and CUL4 associated factor 17
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DOLK dolichol kinase
FBXL6 F-box and leucine-rich repeat protein 6
FGD1 FYVE, RhoGEF and PH domain containing 1
FHOD3 formin homology 2 domain containing 3
FZD8 frizzled class receptor 8
GLDC glycine dehydrogenase (decarboxylating)
GSDMD gasdermin D
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRIP3 HIRA interacting protein 3
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BJ histone cluster 1, H2bj
HIST1H3B histone cluster 1, H3b
IFT54 intraflagellar transport 54
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KLF11 Kruppel-like factor 11
KLF2 Kruppel-like factor 2
KLF7 Kruppel-like factor 7 (ubiquitous)
KRT15 keratin 15, type I
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LRRK1 leucine-rich repeat kinase 1
LZTR1 leucine-zipper-like transcription regulator 1
MDM1 Mdm1 nuclear protein homolog (mouse)
MFSD12 major facilitator superfamily domain containing 12
MGMT O-6-methylguanine-DNA methyltransferase
NARFL nuclear prelamin A recognition factor-like
NCS1 neuronal calcium sensor 1
NPR3 natriuretic peptide receptor 3
NRSN2 neurensin 2
NT5E 5'-nucleotidase, ecto (CD73)
NUP62CL nucleoporin 62kDa C-terminal like
P3H1 prolyl 3-hydroxylase 1
PDE12 phosphodiesterase 12
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PDLIM2 PDZ and LIM domain 2 (mystique)
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLAC8 placenta-specific 8
PLCD1 phospholipase C, delta 1
POTEKP POTE ankyrin domain family, member K, pseudogene
PRMT7 protein arginine methyltransferase 7
PRR15L proline rich 15-like
PRSS2 protease, serine, 2 (trypsin 2)
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTBP2 polypyrimidine tract binding protein 2
PTCD2 pentatricopeptide repeat domain 2
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAI2 retinoic acid induced 2
RARS arginyl-tRNA synthetase
RBL1 retinoblastoma-like 1
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RPUSD2 RNA pseudouridylate synthase domain containing 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC41A3 solute carrier family 41, member 3
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SPAG4 sperm associated antigen 4
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TEX30 testis expressed 30
TNNT1 troponin T type 1 (skeletal, slow)
TRIM58 tripartite motif containing 58
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TSPAN1 tetraspanin 1
TSPAN15 tetraspanin 15
TTLL7 tubulin tyrosine ligase-like family member 7
ZBTB25 zinc finger and BTB domain containing 25
ZC3H12A zinc finger CCCH-type containing 12A
ZDHHC18 zinc finger, DHHC-type containing 18
ZFHX3 zinc finger homeobox 3
ZFP69B ZFP69 zinc finger protein B
ZNF23 zinc finger protein 23
ZNF611 zinc finger protein 611
ZNF862 zinc finger protein 862