piperacetazine-6152 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the piperacetazine-6152 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKR1C1 aldo-keto reductase family 1, member C1
ANGPTL2 angiopoietin-like 2
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOC1 apolipoprotein C-I
ARHGAP26 Rho GTPase activating protein 26
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
B9D1 B9 protein domain 1
BET1L Bet1 golgi vesicular membrane trafficking protein-like
BMP7 bone morphogenetic protein 7
CA9 carbonic anhydrase IX
CARF calcium responsive transcription factor
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDRT1 CMT1A duplicated region transcript 1
CES3 carboxylesterase 3
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CXCL2 chemokine (C-X-C motif) ligand 2
CYP2A7P1 cytochrome P450, family 2, subfamily A, polypeptide 7 pseudogene 1
DDN dendrin
DMTN dematin actin binding protein
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DRD2 dopamine receptor D2
DUSP4 dual specificity phosphatase 4
EML2 echinoderm microtubule associated protein like 2
EPB41 erythrocyte membrane protein band 4.1
EXTL3 exostosin-like glycosyltransferase 3
FBXL18 F-box and leucine-rich repeat protein 18
FERMT1 fermitin family member 1
FGF9 fibroblast growth factor 9
FLOT1 flotillin 1
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2
GIMAP4 GTPase, IMAP family member 4
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GMPR guanosine monophosphate reductase
GPATCH4 G patch domain containing 4
GPR4 G protein-coupled receptor 4
GRIP2 glutamate receptor interacting protein 2
H1F0 H1 histone family, member 0
HDAC11 histone deacetylase 11
HOXB9 homeobox B9
IFT27 intraflagellar transport 27
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KLHL22 kelch-like family member 22
MED25 mediator complex subunit 25
MFSD6 major facilitator superfamily domain containing 6
MXD4 MAX dimerization protein 4
NEK9 NIMA-related kinase 9
NF2 neurofibromin 2 (merlin)
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PADI1 peptidyl arginine deiminase, type I
PAIP2B poly(A) binding protein interacting protein 2B
PAX2 paired box 2
PCLO piccolo presynaptic cytomatrix protein
PCNXL2 pecanex-like 2 (Drosophila)
PDLIM5 PDZ and LIM domain 5
PGAP3 post-GPI attachment to proteins 3
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCE1 phospholipase C, epsilon 1
PNPLA3 patatin-like phospholipase domain containing 3
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PQLC2 PQ loop repeat containing 2
PTBP3 polypyrimidine tract binding protein 3
RASAL2 RAS protein activator like 2
SAMD4A sterile alpha motif domain containing 4A
SCRN3 secernin 3
SH3GL3 SH3-domain GRB2-like 3
SLC45A2 solute carrier family 45, member 2
SLC5A3 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
SMAD3 SMAD family member 3
SMG7 SMG7 nonsense mediated mRNA decay factor
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SOCS7 suppressor of cytokine signaling 7
SORBS1 sorbin and SH3 domain containing 1
SPINK5 serine peptidase inhibitor, Kazal type 5
SYT13 synaptotagmin XIII
TBC1D19 TBC1 domain family, member 19
TCP10 t-complex 10
TLN2 talin 2
TMCC1 transmembrane and coiled-coil domain family 1
TMLHE trimethyllysine hydroxylase, epsilon
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TPMT thiopurine S-methyltransferase
TRIM3 tripartite motif containing 3
TSGA10 testis specific, 10
VTN vitronectin
WDR62 WD repeat domain 62
ZBTB1 zinc finger and BTB domain containing 1
ZER1 zyg-11 related, cell cycle regulator
ZNF442 zinc finger protein 442
ZNF696 zinc finger protein 696

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACAD10 acyl-CoA dehydrogenase family, member 10
ACPP acid phosphatase, prostate
AKTIP AKT interacting protein
ANAPC2 anaphase promoting complex subunit 2
ANKRD40 ankyrin repeat domain 40
ATG10 autophagy related 10
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BGLAP bone gamma-carboxyglutamate (gla) protein
C11ORF63 chromosome 11 open reading frame 63
C22ORF29 chromosome 22 open reading frame 29
CBX7 chromobox homolog 7
CCL20 chemokine (C-C motif) ligand 20
CD3EAP CD3e molecule, epsilon associated protein
CHST10 carbohydrate sulfotransferase 10
CIDEC cell death-inducing DFFA-like effector c
CLCF1 cardiotrophin-like cytokine factor 1
COL9A2 collagen, type IX, alpha 2
COLGALT2 collagen beta(1-O)galactosyltransferase 2
CXORF56 chromosome X open reading frame 56
DCAF17 DDB1 and CUL4 associated factor 17
DNMBP dynamin binding protein
ECM1 extracellular matrix protein 1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM102A family with sequence similarity 102, member A
FAM53B family with sequence similarity 53, member B
FBXL15 F-box and leucine-rich repeat protein 15
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR21 G protein-coupled receptor 21
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HLA-DMB major histocompatibility complex, class II, DM beta
HOXA5 homeobox A5
IDI2-AS1 IDI2 antisense RNA 1
JUNB jun B proto-oncogene
KIAA0754 KIAA0754
KLHL28 kelch-like family member 28
LOC100287590 uncharacterized LOC100287590
LOC390998 ribosomal protein L10 pseudogene
LOC730101 uncharacterized LOC730101
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGEB2 melanoma antigen family B2
MAGEH1 melanoma antigen family H1
MAP6D1 MAP6 domain containing 1
MKS1 Meckel syndrome, type 1
MLYCD malonyl-CoA decarboxylase
MPI mannose phosphate isomerase
MRPL44 mitochondrial ribosomal protein L44
MTG1 mitochondrial ribosome-associated GTPase 1
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NSUN6 NOP2/Sun domain family, member 6
OMG oligodendrocyte myelin glycoprotein
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
PGBD5 piggyBac transposable element derived 5
PIPOX pipecolic acid oxidase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLS1 plastin 1
POLL polymerase (DNA directed), lambda
POLM polymerase (DNA directed), mu
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP1R26 protein phosphatase 1, regulatory subunit 26
PTDSS2 phosphatidylserine synthase 2
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
PYGB phosphorylase, glycogen; brain
QTRT1 queuine tRNA-ribosyltransferase 1
RAB3A RAB3A, member RAS oncogene family
RNF126P1 ring finger protein 126 pseudogene 1
RPP25 ribonuclease P/MRP 25kDa subunit
RUSC2 RUN and SH3 domain containing 2
SCUBE3 signal peptide, CUB domain, EGF-like 3
SETD1A SET domain containing 1A
SETD1B SET domain containing 1B
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
STEAP3 STEAP family member 3, metalloreductase
STX1A syntaxin 1A (brain)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEX40 testis expressed 40
THBS3 thrombospondin 3
TMEM140 transmembrane protein 140
TMEM206 transmembrane protein 206
TMEM212 transmembrane protein 212
TRAF1 TNF receptor-associated factor 1
TRIM9 tripartite motif containing 9
TSPAN13 tetraspanin 13
TSPAN2 tetraspanin 2
TTLL1 tubulin tyrosine ligase-like family member 1
ZBTB38 zinc finger and BTB domain containing 38
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428
ZNF493 zinc finger protein 493
ZNF668 zinc finger protein 668