piperacetazine-7191 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the piperacetazine-7191 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APOC1 apolipoprotein C-I
ARTN artemin
BAIAP2 BAI1-associated protein 2
BTG2 BTG family, member 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCDC25 coiled-coil domain containing 25
CDK13 cyclin-dependent kinase 13
CDKL3 cyclin-dependent kinase-like 3
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CIDEB cell death-inducing DFFA-like effector b
CLCF1 cardiotrophin-like cytokine factor 1
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CRYBG3 beta-gamma crystallin domain containing 3
CTNS cystinosin, lysosomal cystine transporter
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DNAI2 dynein, axonemal, intermediate chain 2
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DVL3 dishevelled segment polarity protein 3
EDRF1 erythroid differentiation regulatory factor 1
EHBP1L1 EH domain binding protein 1-like 1
ELL2 elongation factor, RNA polymerase II, 2
ELSPBP1 epididymal sperm binding protein 1
EPOR erythropoietin receptor
FAM189A2 family with sequence similarity 189, member A2
FHL1 four and a half LIM domains 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GADD45G growth arrest and DNA-damage-inducible, gamma
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BC histone cluster 1, H2bc
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HRASLS2 HRAS-like suppressor 2
IFI35 interferon-induced protein 35
INSIG1 insulin induced gene 1
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
KIFC3 kinesin family member C3
KMT2A lysine (K)-specific methyltransferase 2A
KRT17 keratin 17, type I
LNPEP leucyl/cystinyl aminopeptidase
LPIN1 lipin 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
LZTFL1 leucine zipper transcription factor-like 1
LZTR1 leucine-zipper-like transcription regulator 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MALT1 MALT1 paracaspase
MAP2K5 mitogen-activated protein kinase kinase 5
MAP4 microtubule-associated protein 4
MARK4 MAP/microtubule affinity-regulating kinase 4
MBNL2 muscleblind-like splicing regulator 2
MFN2 mitofusin 2
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MTA2 metastasis associated 1 family, member 2
MVD mevalonate (diphospho) decarboxylase
MVK mevalonate kinase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NUPR1 nuclear protein, transcriptional regulator, 1
OSMR oncostatin M receptor
OVOL1 ovo-like zinc finger 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE4DIP phosphodiesterase 4D interacting protein
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLK4 polo-like kinase 4
RBBP9 retinoblastoma binding protein 9
RCAN1 regulator of calcineurin 1
REM1 RAS (RAD and GEM)-like GTP-binding 1
RGS10 regulator of G-protein signaling 10
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae)
SAMD4A sterile alpha motif domain containing 4A
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SIX3 SIX homeobox 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SUGP1 SURP and G patch domain containing 1
TAZ tafazzin
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRAF3 TNF receptor-associated factor 3
TRD T cell receptor delta locus
UPP1 uridine phosphorylase 1
VEGFB vascular endothelial growth factor B
VIPR2 vasoactive intestinal peptide receptor 2
VN1R1 vomeronasal 1 receptor 1
WDFY3 WD repeat and FYVE domain containing 3
WLS wntless Wnt ligand secretion mediator
YIPF4 Yip1 domain family, member 4
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZFP30 ZFP30 zinc finger protein
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
ALS2CL ALS2 C-terminal like
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARID4A AT rich interactive domain 4A (RBP1-like)
ASPHD1 aspartate beta-hydroxylase domain containing 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BTBD2 BTB (POZ) domain containing 2
C11ORF80 chromosome 11 open reading frame 80
C16ORF59 chromosome 16 open reading frame 59
C19ORF40 chromosome 19 open reading frame 40
C2ORF44 chromosome 2 open reading frame 44
C5 complement component 5
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CENPB centromere protein B, 80kDa
CHEK2 checkpoint kinase 2
CUEDC1 CUE domain containing 1
DGKD diacylglycerol kinase, delta 130kDa
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DNA2 DNA replication helicase/nuclease 2
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNMBP dynamin binding protein
DUSP22 dual specificity phosphatase 22
EIF5A2 eukaryotic translation initiation factor 5A2
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FAM53B family with sequence similarity 53, member B
FGGY FGGY carbohydrate kinase domain containing
FKBPL FK506 binding protein like
GAB2 GRB2-associated binding protein 2
GHR growth hormone receptor
GLI3 GLI family zinc finger 3
GPR19 G protein-coupled receptor 19
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
HECTD4 HECT domain containing E3 ubiquitin protein ligase 4
HIST1H2BO histone cluster 1, H2bo
HIST1H4J histone cluster 1, H4j
IGFLR1 IGF-like family receptor 1
KAT2A K(lysine) acetyltransferase 2A
KIAA0895 KIAA0895
KPTN kaptin (actin binding protein)
LRP3 low density lipoprotein receptor-related protein 3
LRRC37A2 leucine rich repeat containing 37, member A2
MAST3 microtubule associated serine/threonine kinase 3
MATK megakaryocyte-associated tyrosine kinase
MED15 mediator complex subunit 15
MITF microphthalmia-associated transcription factor
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTERF1 mitochondrial transcription termination factor 1
MYO9A myosin IXA
NBEAL2 neurobeachin-like 2
NLK nemo-like kinase
PECR peroxisomal trans-2-enoyl-CoA reductase
PEX14 peroxisomal biogenesis factor 14
PHACTR4 phosphatase and actin regulator 4
PLD3 phospholipase D family, member 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
PNPLA6 patatin-like phospholipase domain containing 6
PTBP2 polypyrimidine tract binding protein 2
RAB33B RAB33B, member RAS oncogene family
RANGRF RAN guanine nucleotide release factor
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIBC2 RIB43A domain with coiled-coils 2
RNF31 ring finger protein 31
RNF38 ring finger protein 38
RPAP1 RNA polymerase II associated protein 1
RPL13P5 ribosomal protein L13 pseudogene 5
SARS2 seryl-tRNA synthetase 2, mitochondrial
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH2D4A SH2 domain containing 4A
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMAD7 SMAD family member 7
STRN4 striatin, calmodulin binding protein 4
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBX19 T-box 19
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TM7SF3 transmembrane 7 superfamily member 3
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMC5 transmembrane channel-like 5
TMUB2 transmembrane and ubiquitin-like domain containing 2
TNS2 tensin 2
TRAIP TRAF interacting protein
TRIM25 tripartite motif containing 25
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSPAN15 tetraspanin 15
TUBA3D tubulin, alpha 3d
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USP6 ubiquitin specific peptidase 6
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VASH2 vasohibin 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR60 WD repeat domain 60
XAB2 XPA binding protein 2
ZBED1 zinc finger, BED-type containing 1
ZCCHC6 zinc finger, CCHC domain containing 6
ZNF180 zinc finger protein 180