| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the piperacillin-3420 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM15 | ADAM metallopeptidase domain 15 |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AMPD3 | adenosine monophosphate deaminase 3 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APOD | apolipoprotein D |
| ARL3 | ADP-ribosylation factor-like 3 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATF6B | activating transcription factor 6 beta |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| CA12 | carbonic anhydrase XII |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CCDC28B | coiled-coil domain containing 28B |
| CDC14B | cell division cycle 14B |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CEP162 | centrosomal protein 162kDa |
| CES3 | carboxylesterase 3 |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CREM | cAMP responsive element modulator |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CUL9 | cullin 9 |
| DHRS12 | dehydrogenase/reductase (SDR family) member 12 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| EMID1 | EMI domain containing 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EXOC7 | exocyst complex component 7 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FAM212B | family with sequence similarity 212, member B |
| FHL1 | four and a half LIM domains 1 |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GP5 | glycoprotein V (platelet) |
| H2AFX | H2A histone family, member X |
| HBEGF | heparin-binding EGF-like growth factor |
| HGFAC | HGF activator |
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A |
| HLA-C | major histocompatibility complex, class I, C |
| HOMER3 | homer scaffolding protein 3 |
| HPX | hemopexin |
| IGHMBP2 | immunoglobulin mu binding protein 2 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IL1RN | interleukin 1 receptor antagonist |
| INPP1 | inositol polyphosphate-1-phosphatase |
| ITM2C | integral membrane protein 2C |
| JUNB | jun B proto-oncogene |
| KIF21B | kinesin family member 21B |
| KITLG | KIT ligand |
| LIG3 | ligase III, DNA, ATP-dependent |
| LMAN1 | lectin, mannose-binding, 1 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 |
| MAP1B | microtubule-associated protein 1B |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 |
| MMP3 | matrix metallopeptidase 3 |
| MUC1 | mucin 1, cell surface associated |
| MUT | methylmalonyl CoA mutase |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NRSN2 | neurensin 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PCDH9 | protocadherin 9 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| POLDIP3 | polymerase (DNA-directed), delta interacting protein 3 |
| POPDC3 | popeye domain containing 3 |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PTN | pleiotrophin |
| RECQL5 | RecQ protein-like 5 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RHOT2 | ras homolog family member T2 |
| RNF122 | ring finger protein 122 |
| RNF39 | ring finger protein 39 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SIRPA | signal-regulatory protein alpha |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SOX13 | SRY (sex determining region Y)-box 13 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SYCP2 | synaptonemal complex protein 2 |
| TAF9B | TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa |
| TBC1D22A | TBC1 domain family, member 22A |
| TIMELESS | timeless circadian clock |
| TP53AIP1 | tumor protein p53 regulated apoptosis inducing protein 1 |
| TRIM21 | tripartite motif containing 21 |
| TSPAN9 | tetraspanin 9 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ABHD4 | abhydrolase domain containing 4 |
| ACVR2B | activin A receptor, type IIB |
| ACYP2 | acylphosphatase 2, muscle type |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BAG4 | BCL2-associated athanogene 4 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CARD8 | caspase recruitment domain family, member 8 |
| CCDC9 | coiled-coil domain containing 9 |
| CDK3 | cyclin-dependent kinase 3 |
| CGA | glycoprotein hormones, alpha polypeptide |
| CISH | cytokine inducible SH2-containing protein |
| CSAD | cysteine sulfinic acid decarboxylase |
| DENND4A | DENN/MADD domain containing 4A |
| DENND4C | DENN/MADD domain containing 4C |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNASE1L1 | deoxyribonuclease I-like 1 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EPPK1 | epiplakin 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERCC5 | excision repair cross-complementation group 5 |
| FEM1C | fem-1 homolog c (C. elegans) |
| FER | fer (fps/fes related) tyrosine kinase |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLTP | glycolipid transfer protein |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIRA | histone cell cycle regulator |
| HIST1H2AE | histone cluster 1, H2ae |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| IFT22 | intraflagellar transport 22 |
| IFT81 | intraflagellar transport 81 |
| IMPACT | impact RWD domain protein |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KIAA0556 | KIAA0556 |
| KLHL21 | kelch-like family member 21 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LMNB1 | lamin B1 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MYL5 | myosin, light chain 5, regulatory |
| MYO1F | myosin IF |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PLD2 | phospholipase D2 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RFWD3 | ring finger and WD repeat domain 3 |
| RNF146 | ring finger protein 146 |
| ROM1 | retinal outer segment membrane protein 1 |
| RUFY2 | RUN and FYVE domain containing 2 |
| SETD1B | SET domain containing 1B |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPAG4 | sperm associated antigen 4 |
| SPATA7 | spermatogenesis associated 7 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TESK2 | testis-specific kinase 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TIPRL | TOR signaling pathway regulator |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMEM2 | transmembrane protein 2 |
| TRAIP | TRAF interacting protein |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein |
| TTC30A | tetratricopeptide repeat domain 30A |
| TUBA3C | tubulin, alpha 3c |
| WDR76 | WD repeat domain 76 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF394 | zinc finger protein 394 |
| ZNF480 | zinc finger protein 480 |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |
| ZNF816 | zinc finger protein 816 |
